Search clinical trials for: onchocerciasis

Total 35 results

Bayer

Not yet recruiting

A Study to Learn About How Much Emodepside Gets Absorbed in the Blood and How Food Affects Its Absorption When Given as a New Type of Tablet to Healthy Participants

Soil-transmitted Helminth Infection | Onchocerciasis (River Blindness)
Bioaster

Not yet recruiting

Development of a New Rapid Diagnostic Test to Support Onchocerciasis Elimination (Obi1)

Healthy Volunteers | Onchocerciasis | Mansonelliasis | Loiasis

Cameroon
Programme National de Lutte contre l'Onchocercose...
Institut de Recherche pour le Developpement

Not yet recruiting

A 3- to 5-day Clinical Trial of Levamisole in Loiasis Infected Subjects (STOP-FiLAR)

Loiasis
Washington University School of Medicine
National Public Health Institute of Liberia

Not yet recruiting

Safety and Efficacy of Novel Combination Regimens for Treatment of Onchocerciasis

Onchocerciasis | Onchocerciasis, Ocular | Tropical Disease | Onchocercal Subcutaneous Nodule | Onchocerca Infection

Liberia
Universiteit Antwerpen
Amref Health Africa

Not yet recruiting

Onchocerciasis-Associated Epilepsy, an Explorative Case-control Study

Epilepsy | Virus | Onchocercal Subcutaneous Nodule

South Sudan
Medicines Development for Global Health

Recruiting

Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas and in Individuals Living in Onchocerciasis Endemic Areas With High Levels of Lymphatic Filariasis Co-endemicity Receiving Concomitant Albendazole

Onchocerciasis

Côte D'Ivoire, Congo, The Democratic Republic of the
Center for Research on Filariasis and Other Tropical...

Not yet recruiting

Evaluation of the Diagnosis Performances of DEC LTS-2 Skin Patch for Onchocerciasis in Central Africa (EOLoa)

Diagnoses Disease | Onchocerciasis | Neglected Diseases | Loiasis

Cameroon
National Institute of Allergy and Infectious Diseases...

Recruiting

Host Response to Infection and Treatment in Filarial Diseases

Filariasis | Helminthiasis | Onchocerciasis | Mansonelliasis | Parasitic Infection

United States
Drugs for Neglected Diseases
Bayer

Active, not recruiting

Emodepside Phase II Trial for Treatment of Onchocerciasis

Onchocerciasis

Ghana, Congo, The Democratic Republic of the
Universiteit Antwerpen
Amref Health Africa

Completed

Effect of Onchocerciasis Elimination Measures on the Incidence of Epilepsy in Maridi, South Sudan (OAEMaridi)

Epilepsy | Onchocerciasis

South Sudan
Universiteit Antwerpen

Completed

Impact of a Bi-annual CDTI on the Incidence of Epilepsy in an Onchocerciasis-endemic Area (OAETanzania)

Epilepsy | Onchocerciasis

Tanzania
Liverpool School of Tropical Medicine
Liverpool University Hospitals NHS Foundation Trust; Covance; Eisai Limited; Subiaco... and other collaborators

Terminated

Development of AWZ1066S, a Small Molecule Anti-Wolbachia Candidate Macrofilaricide Drug (AWOL)

Onchocerciasis | Filariasis, Lymphatic

United Kingdom
AbbVie
Drugs for Neglected Diseases initiative

Terminated

Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of Adult Participants With Onchocerca Volvulus Infection

Onchocerciasis

Congo, The Democratic Republic of the
Medicines Development for Global Health

Active, not recruiting

Safety and Efficacy of Annual or Biannual Doses of Moxidectin or Ivermectin for Onchocerciasis

Onchocerciasis

Congo, The Democratic Republic of the
Center for Research on Filariasis and Other Tropical...

Active, not recruiting

Clinical Trial Evaluating the Safety and Efficacy of Moxidectin 2 mg Ivermectin-controlled in Loa Loa Microfilaremic Patients (EOLoa)

Onchocerciasis, Ocular | Loiasis

Cameroon
Washington University School of Medicine
Case Western Reserve University; University of Health and Allied Sciences

Completed

Safety and Efficacy of IDA for Onchocerciasis (DOLF IDA/Oncho)

Onchocerciasis

Ghana
Swiss Tropical & Public Health Institute
Drugs for Neglected Diseases; Ifakara Health Institute

Completed

PK, Safety and Tolerability of Single and Multiple Doses of Oxfendazole Tablets (HELP-OFZ)

Filariasis

Tanzania
Medicines Development for Global Health

Completed

A Pharmacokinetic and Safety Study of Moxidectin to Identify an Optimal Dose for Treatment of Children 4 to 11 Years

Onchocerciasis

Ghana
Medicines Development for Global Health
World Health Organization

Completed

Study Evaluating Orally Administered Moxidectin In Subjects With Onchocerca Volvulus Infection

Onchocerciasis

Ghana
Washington University School of Medicine

Completed

Mass Drug Administration for Lymphatic Filariasis and Onchocerciasis for Liberia (DOLF-LIBERIA)

Lymphatic Filariasis | Onchocerciasis | Soil Transmitted Helminth (STH) Infections

Liberia
Programme National de Lutte contre l'Onchocercose...

Completed

Clinical Trial Evaluating the Safety and Efficacy of Levamisole in Loa Loa Microfilaremic Patients (EOLoa)

Onchocerciasis, Ocular | Loiasis

Congo
Washington University School of Medicine
Indian Council of Medical Research; Case Western Reserve University

Completed

Death to Onchocerciasis and Lymphatic Filariasis (DOLF) Triple Drug Therapy for Lymphatic Filariasis

Lymphatic Filariasis

Haiti, India, Indonesia, Papua New Guinea
Washington University School of Medicine
Case Western Reserve University; University of Health and Allied Sciences

Completed

Ocular Changes After Ivermectin - (DOLF IVM/Oncho)

Onchocerciasis

Ghana
Washington University School of Medicine

Completed

Optimization of Mass Drug Administration With Existing Drug Regimens for Lymphatic Filariasis and Onchocerciasis (DOLF-Indo)

Lymphatic Filariasis | Soil Transmitted Helminth Infections

Indonesia
Drugs for Neglected Diseases
Bayer; Bill and Melinda Gates Foundation

Completed

First in Man Clinical Trial of Emodepside (BAY 44-4400)

Healthy Volunteers

United Kingdom
Universiteit Antwerpen
European Research Council

Completed

Ivermectin Treatment of Persons With Onchocerciasis-associated Epilepsy (OAETREATe)

Epilepsy

Congo, The Democratic Republic of the
University Hospitals Cleveland Medical Center

Completed

Efficacy of Ivermectin and Albendazole Against Onchocerciasis in the Volta Region, Ghana

Onchocerciasis

Ghana
Robert Colebunders

Completed

Ivermectin Treatment in Patients With Onchocerciasis-associated Epilepsy (OAETREAT)

Epilepsy | Onchocerciasis | Ivermectin

Congo, The Democratic Republic of the
Noguchi Memorial Institute for Medical Research
Ghana Health Service, Neglected Tropical Diseases Program

Completed

Prevalence of LF Infection in Districts Not Included in LF Control Activities

Onchocerciasis | Lymphatic Filariases

Ghana
Heidelberg University

Unknown

Clinical Features and Potential Etiology of Epilepsy and Nodding Syndrome in the Mahenge Area, Ulanga District (NSEC)

Epilepsy | Cognitive Impairment | Onchocerciasis | Nodding Syndrome

Tanzania
Washington University School of Medicine

Completed

Optimization of Mass Drug Administration With Existing Drug Regimens for Lymphatic Filariasis and Onchocerciasis for Ivory Coast (DOLF-Ivory Coast)

Lymphatic Filariasis | Onchocerciasis | Soil Transmitted Helminth (STH) Infections

Côte D'Ivoire
Medicines Development for Global Health
World Health Organization

Completed

Study Comparing Moxidectin And Ivermectin In Subjects With Onchocerca Volvulus Infection

Onchocerciasis

Congo, The Democratic Republic of the, Ghana, Liberia
University Hospitals Cleveland Medical Center
Washington University School of Medicine

Completed

IVM Alone vs ALB + IVM Against Onchocerciasis

Onchocerciasis

Ghana
Pfizer
World Health Organization

Withdrawn

Pediatric Pharmacokinetics And Safety Study Of Moxidectin

Onchocerciasis
Centers for Disease Control and Prevention
University of Alabama at Birmingham; Universidad del Valle, Guatemala

Completed

Clinical Trial of Rifampin and Azithromycin for the Treatment of River Blindness

Onchocerciasis

Guatemala

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