Search clinical trials for: oral itraconazole

Total 17669 results

Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Postgraduate Institute of Medical Education and...

Recruiting

Compare Oral Itraconazole and Standard Care Versus Standard Care Alone in Patients With Non-cystic Fibrosis Related Bronchiectasis With Chronic Aspergillus Infection in Reducing Bronchiectasis Exacerbations (BAIT)

Bronchiectasis | Bronchiectasis Adult

India
Xuanzhu Biopharmaceutical Co., Ltd.

Not yet recruiting

Drug-drug Interaction Study of XZP-3621 Tablet

Healthy Subjects

China
Postgraduate Institute of Medical Education and...

Recruiting

Oral Itraconazole Versus Combination of Systemic Glucorticoids and Oral Itraconazole in CPA-ABPA Overlap Syndrome (GLITZ)

Allergic Bronchopulmonary Aspergillosis | Chronic Pulmonary Aspergillosis

India
Shanghai Zhongshan Hospital

Not yet recruiting

A Prospective Study on Optimizing Treatment for ABPA

Allergic Bronchopulmonary Aspergillosis
Montreal Heart Institute

Recruiting

Evaluation of the Response of Itraconazole and Terbinafine Therapy in Subjects With Crohn's Disease (CD-IT)

Inflammatory Bowel Diseases | Crohn's Disease

Canada
Gynaecologisch Oncologisch Centrum Zuid
Radboud University Medical Center; Maastricht University Medical Center; Erasmus... and other collaborators

Recruiting

Signal TrAnsduction Pathway Activity Analysis in OVarian cancER (STAPOVER)

Recurrent Ovarian Cancer | Therapy-Associated Cancer | Signal Transduction Pathway Deregulation

Netherlands
Postgraduate Institute of Medical Education and...

Active, not recruiting

A Randomized Controlled Trial to Compare the Clinical Outcomes With Six Months of Therapy With Oral Itraconazole Versus Oral Voriconazole for Management of Treatment naïve Subjects With Chronic Pulmonary Aspergillosis

Chronic Pulmonary Aspergillosis

India
Reata, a wholly owned subsidiary of Biogen
Covance

Completed

A Clinical Drug-Drug Interaction (DDI) Study With Omaveloxolone

Healthy Adult Subjects

United States
Daiichi Sankyo Co., Ltd.
AstraZeneca

Completed

Study of DS-8201a for Participants With Advanced Solid Malignant Tumors

Neoplasm Metastasis

Korea, Republic of, Taiwan, Japan
Semmelweis University

Completed

Acute Oral Effects of Heated Tobacco Products

Nicotine Dependence, Cigarettes

Hungary
BioVersys AG
CRU Hungary Kft

Completed

To Evaluate the Effect of Multiple Doses of Itraconazole on the Pharmacokinetics of BV100

Bacterial Infections

Hungary
University of Maryland, Baltimore

Completed

Itraconazole Oral Absorption

Fungal Infection

United States
DICE Therapeutics, Inc.

Completed

A Drug-Drug Interaction Study to Assess the Pharmacokinetics of DC-806 When Orally Administered Alone, When Coadministered With Itraconazole, and When Coadministered With Carbamazepine in Healthy Adult Participants

Healthy Volunteers

United States
Combined Military Hospital Abbottabad

Completed

Comparison of Efficacy of Single Oral Dose Fluconazole and Itraconazole in Patients With Pityriasis Versicolor

Tinea Versicolor

Pakistan
Xenon Pharmaceuticals Inc.

Completed

Safety, Tolerability, and Pharmacokinetics (PK) of Single and Multiple Ascending Oral Doses of XEN1101.

Healthy Volunteers

United Kingdom
Sanofi

Completed

A Study to Assess the Effect of Erythromycin on the Test Medicine (SAR443820) When Given Orally as Tablets to Healthy Adult Male and Female Participants (Part A); and the Effect of Itraconazole on the Test Medicine (SAR443820) When Given Orally as Capsules to Healthy Adult Male Participants (Part B)

Amyotrophic Lateral Sclerosis (Healthy Volunteers)

United States
Pfizer

Completed

A Study Of Oral PF-02341066, A C-Met/Hepatocyte Growth Factor Tyrosine Kinase Inhibitor, In Patients With Advanced Cancer (PROFILE 1001)

Systemic Anaplastic Large-Cell Lymphoma | Non-Small Cell Lung Cancer ALK-positive | Non-Small Cell Lung Cancer c-Met Dependent | Non-Small Cell Lung Cancer ROS Marker Positive | Advanced Malignancies Except Leukemia

United States, Korea, Republic of, Australia, Japan
Combined Military Hospital Abbottabad

Completed

Comparative Study Between Pulse Therapy With Oral Itraconazole Versus Continuous Oral Terbinafine Therapy for Treatment of Onychomycosis

Onychomycosis

Pakistan
Pak Emirates Military Hospital

Completed

Comparison of Efficacy of Double Dose Oral Terbinafine Vs Itraconazole in Treatment of Dermatophyte Infections of Skin.

Terbinafine Adverse Reaction | Dermatophyte Infection | Itraconazole Adverse Reaction

Pakistan
Postgraduate Institute of Medical Education and...

Completed

Six Months Versus 12 Months of Oral Itraconazole Therapy for Management of Treatment naïve Subjects With CPA

Chronic Pulmonary Aspergillosis

India
TherapeuticsMD

Completed

Annovera™ Drug-Drug Interaction Study

Contraception | Women

Canada
F2G Biotech GmbH
Hammersmith Medicines Research

Completed

Drug-drug Interaction (DDI) Study to Assess Effect of Itraconazole and Rifampicin Upon Olorofim

Healthy

United Kingdom
Assembly Biosciences

Completed

A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy Adults

Chronic Hepatitis B

United States
Pfizer

Completed

Effect of Multiple Doses of Itraconazole on the Pharmacokinetics of a Single-Dose of PF-06651600 in Healthy Participants

Healthy Participants

Belgium
Hospital de Clinicas de Porto Alegre

Unknown

Use Of Oral Itraconazole In Patients With Locally Limited Basocellular Carcinoma Of Skin.

Basal Cell Carcinoma | Hedgehog Pathway

Brazil
Xian-Janssen Pharmaceutical Ltd.

Terminated

A Study Comparing the Efficacy of Intravenous Followed by Oral Itraconazole With Intravenous Caspofungin For Empiric Antifungal Therapy in Neutropenic Participants With Hematological Malignancy

Hematologic Neoplasms

China
Boehringer Ingelheim

Completed

Effect of Multiple Doses of Itraconazole on the Pharmacokinetics of a Single Oral Dose of BI 1026706 in Healthy Male Subjects

Healthy

Germany
Corcept Therapeutics

Completed

Mifepristone Drug-Drug Interaction Study With CYP3A Inhibitor

Healthy | Drug Interaction Potentiation

United States
AstraZeneca

Completed

To Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of Olaparib, and the Effect of Olaparib on QT Interval Following Oral Dosing of a Tablet Formulation to Patients With Advanced Solid Tumours

Solid Tumours

Belgium, Denmark, United Kingdom, Netherlands
Bayer

Completed

Study in Postmenopausal Women to Investigate the Drug-drug Interaction (DDI) Between Itraconazole(ITZ) and Orally Administered Vilaprisan; Absolute Bioavailability Using Intravenous Microtracer Dose of [14C]Vilaprisan

Clinical Trial, Phase I

United Kingdom
KU Leuven
Agentschap voor Innovatie door Wetenschap en Technologie

Completed

Risk of QT-prolongation and Torsade de Pointes in Patients Treated With Acute Medication in a University Hospital (RISQ-PATH)

Delirium | QT-prolongation

Belgium
Boehringer Ingelheim

Completed

Relative Bioavailability of a Single Oral Dose of BI 425809 When Administered Alone or in Combination With Multiple Oral Doses of Itraconazole in Healthy Male Subjects

Healthy

Germany
Boehringer Ingelheim

Completed

Effect of Cytochrome P 450 3A4 Inhibition by Itraconazole on the Single Oral Dose Pharmacokinetics of Cilobradine

Healthy
Janssen Pharmaceutical K.K.

Completed

A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection

Mycoses | Candidiasis | Neutropenia | Aspergillosis | Cryptococcosis | Histoplasmosis | Blastomycosis

Japan
Xian-Janssen Pharmaceutical Ltd.

Completed

An Efficacy and Safety Study of Itraconazole Sequential Therapy (Intravenous Injection Followed by Oral Solution) in Invasive Pulmonary Fungal Infections

Pulmonary Fungal Infection
Zhejiang University
Guangdong Provincial People's Hospital; Shanghai General Hospital, Shanghai... and other collaborators

Completed

Efficacy of Itraconazole as Secondary Prophylaxis in Patients Undergoing Allogeneic Stem Cell Transplantation or Chemotherapy With Prior Invasive Fungal Infection

Invasive Fungal Infection

China
Novartis Pharmaceuticals

Terminated

An Exploratory Study to Assess Multiple Doses of Omalizumab in Patients With Cystic Fibrosis Complicated by Acute Bronchopulmonary Aspergillosis (ABPA)

Cystic Fibrosis | Allergic Bronchopulmonary Aspergillosis

United Kingdom, Germany, Belgium, Italy, Netherlands
Turku University Hospital

Completed

Effect of Itraconazole and Ticlopidine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol

Pharmacokinetics | Pharmacodynamics

Finland
Samsung Medical Center
Janssen, LP

Terminated

Evaluation of Antifungal Prophylaxis on Graft-versus-host Disease (GVHD) Patients (ITRAG)

Graft vs Host Disease

Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Prospective, Randomized, Double-Blind Clinical Trial Comparing Itraconazole Oral Solution in Cyclodextrin to Placebo in the Treatment of Aspergilloma

Aspergillosis | Lung Diseases, Fungal

United States
Guangzhou General Hospital of Guangzhou Military...
First Affiliated Hospital, Sun Yat-Sen University; Nanfang Hospital of Southern... and other collaborators

Unknown

Long-term Versus Short-term Sequential Therapy (Intravenous Itraconazole Followed by Oral Solution) of Itraconazole as Primary Prophylaxis in Patients Undergoing Allogeneic Stem Cell Transplantation

Hematological Diseases | Allogeneic Stem Cell Transplantation

China
Janssen, LP

Completed

An Open Study of the Effect of Itraconazole Oral Solution for the Treatment of Fluconazole Refractory Oropharyngeal Candidiasis in HIV-Positive Subjects.

HIV Infections | Candidiasis, Oral

United States
Janssen, LP

Completed

Study of Itraconazole in Patients With Advanced HIV Infection

HIV Infections

United States
Janssen Pharmaceuticals

Completed

Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.

HIV Infections | Candidiasis, Esophageal

United States
Janssen, LP

Completed

A Study of Treatments for Fungal Infections of the Mouth and Throat in HIV-Infected Patients Who Have Had Success With Itraconazole But Not With Fluconazole

HIV Infections | Candidiasis, Oral

United States
University of Aarhus

Not yet recruiting

Dysphagia and Quality of Life in Patients With Oral Squamous Cell Carcinoma Before and After Treatment

Quality of Life | Dysphagia | Oral Cavity Cancer

Denmark
Ain Shams University
Dar EL Salam Cancer Hospital

Recruiting

Effect of Alpha Lipoic Acid on Chemotherapy Induced Neurological Changes in Breast Cancer Patients

Breast Cancer | Chemotherapy | Neurologic Disorder | Paclitaxel | Alpha Lipoic Acid

Egypt
University of Giessen

Recruiting

Topical Application of PRF Before Radiation Therapy (PRF)

PRF

Germany
AstraZeneca
Parexel

Not yet recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States

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