Search clinical trials for: pilot open label trial

Total 55548 results

University of Michigan

Not yet recruiting

Pilot Open-Label Trial of Resistant Potato Starch in Patients With Cirrhosis and Overt Hepatic Encephalopathy

Hepatic Encephalopathy | Cirrhosis

United States
Johns Hopkins University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

CAPABLE Transplant

Depression | Quality of Life | End Stage Renal Disease | Disability Physical

United States
Centre Hospitalier St Anne

Recruiting

Transcranial Ultrasonic Stimulation in Treatment-resistant Depression : an Open-label Pilot Trial (StimulUS)

Treatment Resistant Depression

France
University of Stellenbosch
University of Rochester; Fogarty International Center of the National Institute...

Recruiting

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (SMART)

Metabolic Syndrome | HIV Seropositivity

South Africa
Centre for Addiction and Mental Health

Recruiting

Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression (DEEPP)

Suicidality | Bipolar Disorder (BD)

Canada
NovoCure GmbH
Merck Sharp & Dohme LLC

Recruiting

EF-36/Keynote B36: A Pilot, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant With Pembrolizumab for First Line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer (KEYNOTE B36)

Non-small Cell Lung Cancer

United States
St. Jude Children's Research Hospital
National Cancer Institute (NCI); Conquer Cancer Foundation; St. Baldrick's Foundation

Recruiting

An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

PreDiabetes | Adult Children

United States
M.D. Anderson Cancer Center
Zymeworks BC Inc.

Active, not recruiting

A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)

Breast Cancer | HER2-positive

United States
Johns Hopkins University
National Institute on Disability, Independent Living, and Rehabilitation... and other collaborators

Completed

CAPABLE Family Pilot - Adapting CAPABLE for Older Adults With Mild Cognitive Impairment (MCI)/Early Stage Dementia and Their Care Partners

Depression | Quality of Life | Caregiver Burden | Mild Cognitive Impairment | Disability Physical | Dementia, Mild | Impairment, Cognitive

United States
Centre for Addiction and Mental Health

Completed

Intranasal Ketamine in Ultra-REsistant Depression (SURE-ECT Non Responders) (SURE-ECT)

Depression

Canada
Hospital Universitari de Bellvitge

Completed

Feasibility and Effect of a Multidisciplinary Telematics Approach for Chronic Non-specific Low Back Pain: a Randomized, Open-label, Controlled, Pilot Clinical Trial. Study Protocol

Low Back Pain

Spain
Steeve Provencher
Resverlogix Corp

Completed

Apabetalone for Pulmonary Arterial Hypertension: a Pilot Study (APPRoAcH-p)

Pulmonary Arterial Hypertension

Canada
Oregon Health and Science University
Pfizer

Completed

Tofacitinib Hypothesis-generating, Pilot Study for Corticosteroid-Dependent Sarcoidosis

Sarcoidosis | Sarcoidosis, Pulmonary | Sarcoidosis Lung

United States
Hoffmann-La Roche

Terminated

A Study of Balovaptan in Adults With Autism Spectrum Disorder With a 2-Year Open-Label Extension

Autism Spectrum Disorder

United States, Canada, France, Italy, Spain, United Kingdom
Adam Boxer

Completed

A 6 Month, Open-Label, Pilot Futility Clinical Trial of Oral Salsalate for Progressive Supranuclear Palsy

Progressive Supranuclear Palsy

United States
Bright Vision Hospital

Unknown

Efficacy and Feasibility of De-prescribing Rounds in a Singapore Rehabilitative Hospital- a Pilot Randomized Controlled Trial

Deprescribing | Multi-disciplinary | Rounds

Singapore
Fundacion SEIMC-GESIDA

Completed

A Phase IV, Open-label, Randomised, Pilot Clinical Trial Designed to Evaluate the Potential Neurotoxicity of Dolutegravir/Lamivudine/Abacavir in Neurosymptomatic HIV Patients and Its Reversibility After Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide. DREAM Study (DREAM)

HIV Infections

Spain
Ruijin Hospital

Terminated

Remotely Programmed Deep Brain Stimulation of the Bilateral Habenula for Treatment- Resistant Major Depression: An Open Label Pilot Trial

Treatment Resistant Major Depressive Disorder

China
Stanford University

Withdrawn

Open-label Pilot Clinical Trial of Oral Ivermectin to Treat Atopic Dermatitis

Atopic Dermatitis

United States
The Leeds Teaching Hospitals NHS Trust

Unknown

A Prospective, Open Label, Pilot Study of Patient OutcoMes Following Successful TriAl of High Frequency SpInal CorD Stimulation at 10kHz (HF10™) Leading to Permanent Implant Compared to Trial Failure and Standard CarE for the TreatmeNt of Persistent Low BACK Pain of Neuropathic Origin (Maiden Back)

Palliative Care

United Kingdom
University of Washington
Gilead Sciences; Clinique des Maladies Infectieuses Ibrahima DIOP Mar/CRCF,...

Completed

An Open Label Trial of Stribild for Antiretroviral (ARV)-naïve HIV-2 Infected Adults in Dakar, Senegal (Stribild HIV-2)

HIV-2 Infection

Senegal
Medical University of South Carolina
National Institute on Drug Abuse (NIDA); American Academy of Child Adolescent...

Completed

An Open-Label Trial of N-Acetylcysteine in Cannabis Dependent Adolescents (NAC MJ Pilot)

Cannabis Dependence

United States
Population Council

Completed

A Two-part Trial Assessing the Effects of 7α-methyl-19-nortestosterone (MENT) on Blood Pressure in Normal Men: an Open-label Pilot Study Followed by a Randomized, Double-blind, Placebo-controlled Study

Blood Pressure

United States
Hospital for Special Surgery, New York
National Institutes of Health (NIH); Genzyme, a Sanofi Company

Completed

An Open Label Trial for Treating Carpometacarpal Osteoarthritis of the Thumb: Pilot Study

Carpometacarpal Osteoarthritis

United States
Yale University

Completed

An Open-Label Pilot Trial of Alpha Lipoic Acid (ALA) for Weight Loss in Schizophrenia (ALA)

Obesity | Schizophrenia | Weight Loss

United States
Nationwide Children's Hospital
Ohio State University

Unknown

Vitamin D in Pediatric Asthma: a Randomized Controlled Open-label Pilot Trial (D-Asthma)

Vitamin D Deficiency | Asthma

United States
Northwell Health

Withdrawn

Open Label Pilot Trial of Rituximab in Lupus Membranous Nephritis

Lupus Nephritis
Medidata Solutions
Miami Research Associates

Completed

A Pilot Open Label Clinical Trial to Evaluate the Combined Impact of Two Mobile Health Products on Health Outcomes in Overweight Adults With Type 2 Diabetes

Type 2 Diabetes Mellitus

United States
Centre hospitalier de l'Université de Montréal...
Radiological Society of North America; Centre de Recherche du Centre Hospitalier... and other collaborators

Completed

Study of Liraglutide Versus Insulin on Liver Fat Fraction in Patients With Type 2 Diabetes (LIRAINS)

Type 2 Diabetes | Nonalcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis

Canada
Cooperative International Neuromuscular Research...

Completed

KUL0401: An Open-label Pilot Study of Oxatomide in Steroid-Naive Duchenne Muscular Dystrophy

Muscular Dystrophy, Duchenne

United States
Bristol-Myers Squibb

Completed

A Pilot Open Label Trial of HIV Therapy With d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects With Early Asymptomatic HIV Infection

HIV Infections

United States
Bristol-Myers Squibb

Completed

A Pilot Open Label Trial of HIV Therapy With d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects With Recent HIV Infection

HIV Infections

United States
Cooperative International Neuromuscular Research...

Completed

An Open-label Pilot Study of Coenzyme Q10 in Steroid-Treated Duchenne Muscular Dystrophy

Muscular Dystrophy, Duchenne

United States
Assistance Publique - Hôpitaux de Paris

Completed

Mazindol in Children With ADHD : Open-label, Efficacy, Safety and Pharmacokinetic Pilot Trial (MAZDAH)

Attention Deficit Hyperactivity Disorder

France
Charite University, Berlin, Germany
Bristol-Myers Squibb

Unknown

Pilot Open Label Clinical Trial With Abatacept in Ankylosing Spondylitis (Aba-AS-01)

Ankylosing Spondylitis

Germany
Agouron Pharmaceuticals

Completed

A Pilot, Open-Label, Phase II, Randomized Study to Determine the Effects of Viracept on the Outcome of Cutaneous and Mucosal KS in AIDS Patients With CD4 <= 500 Cells/mm3

HIV Infections | Sarcoma, Kaposi

United States
Liverpool Heart and Chest Hospital NHS Foundation...
Biolife LLC

Not yet recruiting

Statseal® for Central Venous Catheter Insertion Sites in Critical Care (SCENIC)

Vascular Access | Critical Care | Central Venous Catheter | Central Line | Hemostatic

United Kingdom
Jazz Pharmaceuticals

Not yet recruiting

A Phase 3, Randomized, Open-label, Controlled Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

Metastatic HER2-positive Breast Cancer
Sunnybrook Health Sciences Centre

Recruiting

Accelerated, Theta-burst Stimulation for the Treatment of Post-concussion Syndrome - Open-label Pilot Study

Post-Concussion Syndrome

Canada
Ferring Pharmaceuticals

Not yet recruiting

A Phase 4, Multi-center, Open Label Trial to Evaluate Efficacy of Retreatment With Nadofaragene Firadenovec in Subjects With CIS ± High-grade Ta/T1 and no Complete Response to First Nadofaragene Firadenovec Dose (ABLE-42)

Bladder Cancer | CIS | Ta/T1
GlaxoSmithKline

Recruiting

Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma

Asthma

United States, Canada, Argentina, Australia, Japan, Korea, Republic of, Taiwan
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy of Intraoperative Use of 20% Albumin Combined With Ringer Lactate Versus Ringer Lactate During Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy (ALBUCHIP)

Postoperative Complications | Peritoneal Neoplasms | Fluid Therapy | Hyperthermic Intraperitoneal Chemotherapy | Intraoperative Care
Fondation Ophtalmologique Adolphe de Rothschild

Not yet recruiting

Immediate Corticosteroid Therapy and Rituximab to Prevent Generalization in Ocular Myasthenia: a PROBE Multicenter Open-label Randomized Controlled Trial. (IMCOMG)

Ocular Myasthenia Gravis
Massachusetts General Hospital
Harvard Medical School (HMS and HSDM)

Recruiting

Open Pilot Trial of a Mind-Body Sexual Well-Being Intervention for Female GI Cancer Survivors

Colorectal Cancer | Sexual Dysfunction | Anal Cancer

United States
Sir Ganga Ram Hospital

Recruiting

Vegetarian Versus Non Vegetarian Based Diet in the Recurrence of Hepatic Encephalopathy in Patients With Cirrhosis: An Open Label Pilot Study

Hepatic Encephalopathy

India
Lindsey Russell, MD
Napo Pharmaceuticals, Inc.

Not yet recruiting

Open-Label Pilot Study With Crofelemer in Patients With Short Bowel Syndrome

Short Bowel Syndrome

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Recruiting

Open-label Trial Characterizing the PK of 3 SC Olanzapine Extended-release Formulations in Participants With Schizophrenia/Schizoaffective Disorder

Schizophrenia, Schizoaffective Disorder

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Recruiting

An Open-Label Trial to Assess the Comparative Bioavailability of TV-44749 to Oral Olanzapine in Participants With Schizophrenia

Schizophrenia

United States
Studio Osteopatico Busto Arsizio

Recruiting

Open-label Placebo in Manual Therapy

Low Back Pain, Recurrent

Italy
The Fourth Affiliated Hospital of China Medical...

Recruiting

A Prospective, Experimental, Multicenter, Open-label, Randomized, Controlled Trial of 3-month Dual Antiplatelet Therapy Followed by Ticagrelor Versus 6-month Dual Antiplatelet Therapy Followed by Ticagrelor After Implanting Bridge

Brain Disease | Vertebral Artery Stenosis

China

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