Search clinical trials for: sGC

Total 111 results

Vojtech Melenovsky, MD, PhD

Not yet recruiting

Metabolic Response to Iniciation of Heart Failure Therapy (GliF)

Heart Failure

Czechia
Istanbul University - Cerrahpasa (IUC)

Not yet recruiting

A New Approach in Intensive Care Unit Consciousness Assessment: FIVE Score

Unconsciousness | Traumatic Brain Injury | Subarachnoid Hemorrhage | Coma | Infratentorial Neoplasms | Epilepsy, Temporal Lobe | Assessment, Self | Intensive Care Neurological Disorder | Arnold Chiari Malformation | Cerebrovascular Event | Postoperative Intracranial Hematoma | Postoperative Intracranial Haemorrhage and other conditions

Turkey
RenJi Hospital

Recruiting

[68Ga] NOTA-SGC8 in the Staging of Bladder Cancer

Bladder Cancer

China
Georgetown University

Not yet recruiting

Glucose-Guided Eating Pilot (GET CHARGED)

Prediabetes | Postmenopausal | Adolescent and Young Adult (AYA) Cancer Survivors
Tandem Diabetes Care, Inc.

Not yet recruiting

Sigi Insulin Management System - A First-in-Human Study in Adults With Type 1 Diabetes (SigiFIH)

Type 1 Diabetes
Oregon Health and Science University

Recruiting

DailyDose Smart Snack Study for T1D on MDI

Type 1 Diabetes Mellitus With Hypoglycemia

United States
Fudan University

Recruiting

A Phase II Study of Advanced Salivary Gland Carcinoma Based on Molecular Typing

Advanced Salivary Gland Carcinoma

China
Eli Lilly and Company

Recruiting

A Study of LY8888AX in Participants Using a Connected Insulin Management Platform

Type 1 Diabetes | Type 2 Diabetes | Type 2 Diabetes Treated With Insulin

France
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; University of Cambridge; University of Newcastle Upon-Tyne and other collaborators

Recruiting

Pulmonary Hypertension: Intensification and Personalisation of Combination Rx (PHoenix)

Pulmonary Arterial Hypertension

United Kingdom
Palo Alto Medical Foundation
Emory University; Abbott Diabetes Care

Recruiting

FreeStyle Libre 2 Discharge Trial

Diabetes Mellitus, Type 2 | Hypoglycemia

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery (SOLSTICE)

Vascular Diseases | Endothelial Dysfunction | Kidney Injury | Brain Disease | Vascular Inflammation

United States
Uludag University

Recruiting

Assignment of the Verbal Component Score and Addition of Pupil Reaction to the Glasgow Coma Scale

Brain Injuries, Traumatic

Turkey
University Health Network, Toronto
Weston Brain Institute

Recruiting

Subgenual Cingulate Deep Brain STIMulation for Apathetic Behavioral Variant FRONtotemporal Dementia (FRONSTIM)

Frontotemporal Dementia | Deep Brain Stimulation

Canada
Medical University of Gdansk

Not yet recruiting

Continuous Glucose Monitoring for Emergency Laparotomy (CLUE)

Hyperglycemia | Infections | Hypoglycemia | Surgical Site Infection | Peritonitis

Poland
Merck Sharp & Dohme LLC

Recruiting

MK-5475-013 INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of MK-5475 (an Inhaled sGC Stimulator) in Adults With PH-COPD

Chronic Obstructive Pulmonary Disease | Pulmonary Hypertension

United States, Korea, Republic of, Australia, Germany, Spain, Italy, Switzerland, France, Argentina, Colombia, Israel, Austria, Mexico, United Kingdom, Belgium, Turkey, Peru, South Africa
Huazhong University of Science and Technology
Wuhan Asia Heart Hospital

Not yet recruiting

Retrospective Data Analysis on the Application of Swan-Ganz Catheter in Cardiac Surgery

Postoperative Complications
Columbia University
DexCom, Inc.

Not yet recruiting

Remote Glucose Monitoring System in Hospitalized Patients With Diabetic Ketoacidosis (DKA)

Diabetic Ketoacidosis

United States
Shanghai Cancer Hospital, China

Recruiting

Abscopal Effect of Radiotherapy in Combination With rhGM-CSF for Advanced Thymic Epithelial Tumours

Thymoma

China
University of Wisconsin, Madison
DexCom, Inc.

Recruiting

AT GOAL: Adopting Technology for Glucose Optimization and Lifestyle in Pregnancy

Type2Diabetes | Pregnancy in Diabetic

United States
DexCom, Inc.

Recruiting

Performance of the Dexcom Continuous Glucose Monitoring (CGM) System in Pregnant Women With Diabetes Mellitus

Diabetes Mellitus

United States
Senseonics, Inc.

Recruiting

Eversense® Non-adjunctive Use Post Approval Study (NA-PAS)

Diabetes

United States
Emory University
DexCom, Inc.

Recruiting

Dexcom CGM in Long-term Care

Diabetes Mellitus, Type 2 | Diabetes

United States
Shanghai Cancer Hospital, China

Not yet recruiting

Abscopal Effect of SBRT in Combination With rhGM-CSF and INF-α 2b for Metastatic Thymic Epithelial Tumors

Thymic Epithelial Tumor

China
National Cancer Institute, Naples

Recruiting

Endometrial Cancer Conservative Treatment (E.C.Co). A Multicentre Archive

Endometrial Cancer

United States, Australia, Austria, Belgium, Canada, China, Denmark, France, Germany, Ireland, Italy, Japan, Korea, Republic of, Netherlands, Spain, United Kingdom
Virginia Commonwealth University
Washington University School of Medicine; University of Iowa; University of Minnesota and other collaborators

Recruiting

Defining Clinical Endpoints in Limb Girdle Muscular Dystrophy (LGMD) (GRASP-01-001)

Muscular Dystrophies | Limb Girdle Muscular Dystrophy

United States, United Kingdom
Neutec Ar-Ge San ve Tic A.Ş

Recruiting

Efficacy and Safety of Modified Release Cefpodoxime Formulation in the Treatment of Acute Sinusitis.

Sinusitis | Rhinosinusitis | Sinus Infection | Sinusitis, Acute | Rhinosinusitis Acute

Turkey
Pirogov Russian National Research Medical University

Recruiting

Caprini Score in Venous Surgery: a Prospective Cohort Study (CAPSIVS)

Varicose Veins | Venous Thromboembolism

Russian Federation
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of the Efficacy and Safety of MK-5475 in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)

Pulmonary Arterial Hypertension | Hypertension, Pulmonary

United States, Argentina, Australia, Belgium, Canada, Colombia, France, Germany, Greece, Israel, Italy, Mexico, New Zealand, Poland, Russian Federation, Sweden, Turkey, United Kingdom
Central Hospital, Nancy, France

Completed

Level of Deprivation Assessment in a Population of Short-bowel Syndrome Patients With Intestinal Failure (PRECAR-SGC)

Short Bowel Syndrome | Intestinal Failure | Deprivation, Psychosocial

France
Poseida Therapeutics, Inc.

Active, not recruiting

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

Neoplasms | Neoplasms by Histologic Type | Urogenital Neoplasms | Neoplasms by Site | Genital Neoplasms, Male | Prostatic Neoplasms | Adenoid Cystic Carcinoma | Mucoepidermoid Carcinoma | Prostate Cancer | Prostatic Neoplasms, Castration-Resistant | Metastatic Castration-resistant Prostate Cancer | Neoplasms... and other conditions

United States
Sansum Diabetes Research Institute
Mayo Clinic; Icahn School of Medicine at Mount Sinai; Harvard University

Completed

Longitudinal Observation of Insulin Requirements and Sensor Use in Pregnancy (LOIS-P)

Type 1 Diabetes Mellitus | Pregnancy in Diabetics

United States
Bayer

Completed

Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Riociguat for Chronic Thromboembolic Pulmonary Hypertension (CTEPH ) (JPMS-CTEPH)

Hypertension, Pulmonary

Japan
Emory University

Completed

Continuous Glucose Monitoring in Patients With End-Stage Kidney Disease and Burnt-Out Diabetes

End Stage Kidney Disease

United States
Imperial College London
London Ambulance Service

Terminated

Assessment of the Impact of Real-Time Continuous Glucose Monitoring on People Presenting With Severe Hypoglycaemia (AIR-CGM)

Hypoglycemia | Diabetes Mellitus, Type 1 | Hypoglycemia Unawareness

United Kingdom
Vastra Gotaland Region

Completed

Accuracy and Treatment Experience of Two Glucose Monitoring Systems Tested in Patients With Type 1 Diabetes and Renal Impairment

Renal Impairment | Diabetes Mellitus Complication

Sweden
Bayer

Completed

Prospective, Non-interventional, Multi-center, Post-authorization Safety Study of Riociguat for Pulmonary Arterial Hypertension (PAH) (JPMS-PAH)

Hypertension, Pulmonary

Japan
Bayer

Completed

A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With CTEPH. (CHEST-1)

Pulmonary Hypertension

Belgium, France, Spain, Turkey, Portugal, Taiwan, Japan, United States, Switzerland, Korea, Republic of, Austria, Canada, China, Denmark, Germany, Russian Federation, Mexico, Argentina, Netherlands, Italy, Poland, United Kingdom, Au... and more
Assistance Publique - Hôpitaux de Paris

Active, not recruiting

Sarcopenia and Short Bowel Syndrome (SARCO-SGC)

Short Bowel Syndrome

France
Bayer

Completed

BAY63-2521 - Long-term Extension Study in Patients With Chronic Thromboembolic Pulmonary Hypertension (CHEST-2)

Pulmonary Hypertension

Belgium, France, Spain, Turkey, Portugal, Taiwan, Japan, United States, Switzerland, Korea, Republic of, Austria, Canada, China, Denmark, Germany, Mexico, Russian Federation, Argentina, Italy, Poland, Australia, Brazil, Czechia, United... and more
Bayer

Terminated

Study to Find the Highest Safe Dose of Soluble Guanylate Cyclase (sGC) Activator, BAY 1211163 Administered as Multiple Doses by Inhalation to Patients Who Cannot Breathe by Their Own and Suffer From a Type of Lung Failure That Causes Fluid to Build up in the Lungs Making Breathing Difficult (ARDS)

Acute Respiratory Distress Syndrome

Germany
Cantonal Hospital of St. Gallen

Completed

Long Term Efficacy of Sacral Nerve Modulation (SNM) in Patients With Constipation or Stool Incontinence

Constipation | Fecal Incontinence
Johns Hopkins University

Completed

CGM Use in Children With Type 2 Diabetes (IMPaCT2)

Type 2 Diabetes | Hyperglycemia Due to Type 2 Diabetes Mellitus

United States
Baylor Research Institute

Enrolling by invitation

Continuous Glucose Monitoring of Hospitalized Patients With Diabetes

Diabetes Mellitus | Diabetes | Glucose, Low Blood | Glucose, High Blood

United States
Cyclerion Therapeutics

Completed

A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD) (STRONG SCD)

Sickle Cell Disease

United States, United Kingdom, Lebanon
Assistance Publique - Hôpitaux de Paris

Completed

Non-invasive Airway Management of Comatose Poisoned Emergency Patients (NICO)

Poisoning | Comatose | Consciousness, Level Altered

France
Bayer

Completed

A Study to Learn How Well a Monitoring System Called Continuous Glucose Monitoring (CGM) Which Measures Glucose on an Ongoing Basis Works and How Safe it is in Chinese Patients in Usual Practice (CareMins)

Diabetes Mellitus | Continuous Glucose Monitoring

China
Blanchard Valley Health System

Enrolling by invitation

Community Glucose Monitoring Project (CMGProject)

Type 2 Diabetes

United States
Universitaire Ziekenhuizen KU Leuven
DexCom, Inc.

Completed

Comparing Continuous With Flash Glucose Monitoring in Adults With Type 1 Diabetes (ALERTT1)

Type 1 Diabetes Mellitus

Belgium
Ipsen

Completed

Study to Evaluate Effects of DYSPORT® Injected in Lower and Upper Limb Combined With Guided Self-Rehabilitation Contract (GSC) (ENGAGE)

Spastic Hemiparesis

United States, Russian Federation, Czechia, France
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Kidney Disease as Measured by Albuminuria

Type 2 Diabetes Mellitus With Diabetic Nephropathy

United States

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