Search clinical trials for: severe bone defects

Total 39677 results

Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Paul Szabolcs

Recruiting

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC (PRO-RIC)

Congenital Bone Marrow Failure Syndromes | Inflammatory Conditions | Primary Immunodeficiency (PID) | Inherited Metabolic Disorders (IMD) | Hereditary Anemias

United States
Paul Szabolcs

Recruiting

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT (HSCT+RIC)

Congenital Bone Marrow Failure Syndromes | Inflammatory Conditions | Primary Immunodeficiency (PID) | Inherited Metabolic Disorders (IMD) | Hereditary Anemias | Systemic Juvenile Idiopathic Arthritis (sJIA)

United States
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States
Mayo Clinic

Terminated

Erenumab For Treatment of Hemicrania Continua

Hemicrania Continua

United States
Aesculap AG

Completed

Follow-Up of the Prevision® Hip Stem (PRESPECT)

Periprosthetic Fracture Around Prosthetic Joint Implant | Aseptic Loosening of Prosthetic Joint

Germany
Dr R Viswa Chandra

Recruiting

Efficacy of Insulin Like Growth Factor-1(IGF-1) on Bone Regeneration in Intrabony Defects : A Clinico-radiograph Study

Intrabony Periodontal Defect

India
Peking Union Medical College Hospital

Not yet recruiting

A Prospective Study on the Treatment of Recurrent/Refractory/Intolerable NSAA With Lusutrombopag

Aplastic Anemia

China
Stanford University
American Heart Association

Not yet recruiting

Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries (MVP-ANOCA)

Angina Pectoris | Microvascular Angina | Vasospastic Angina | Myocardial Bridge of Coronary Artery

United States
Masonic Cancer Center, University of Minnesota

Not yet recruiting

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

Acquired Pure Red Cell Aplasia | Paroxysmal Nocturnal Hemoglobinuria | Severe Aplastic Anemia | Acquired Amegakaryocytic Thrombocytopenia
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

External Mastalgia-oil Versus Oral Tamoxifen in Premenopausal Women With Severe Mastalgia

Mastalgia

China
University of Pavia

Not yet recruiting

Clinical Efficacy of Calcium and Sodium Phosphosilicate (Novamin) in the Treatment of MIH (Molar Incisor Hypolimineralization) in Pediatric Patients

Molar Incisor Hypomineralization

Italy
Hematology department of the 920th hospital

Recruiting

Clinical Study on Modified Allogeneic Hematopoietic Stem Cell Transplantation Regimen for Severe Aplastic Anemia

Severe Aplastic Anemia

China
Capital Medical University

Not yet recruiting

Multiple Electrolytes Injection (II) and Normal Saline on Hyperchloremia in Severe Hemorrhagic Stroke (MERIT)

Hemorrhagic Stroke | Critical Care | Hyperchloremia

China
Universidad Nacional Autonoma de Mexico

Recruiting

Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study

Molar Incisor Hypomineralization

Mexico
Peking University Third Hospital

Recruiting

The Clinical Study of 3D-printed Magnesium Alloy Prosthesis With Controllable Degradation Rate in the Repair of Periarticular Bone Defects

Degradation of Magnesium Alloy Prosthesis and New Bone Regeneration

China
Cairo University

Recruiting

Clinical and Radiographic Evaluation of Using the Entire Papilla Preservation Technique With and Without Autogenous Bone Graft and Injectable Platelet Rich Fibrin in Treatment of Periodontal Intraosseous Defects

Isolated Intrabony Periodontal Defects in Patients With Periodontitis

Egypt
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Effect of RAS/MAPK Pathway Hyperactivation on Growth' and Bone' Profile of the RASopathies (3776)

Noonan Syndrome | Costello Syndrome | RASopathy | Cardio-Facio-Cutaneous Syndrome

Italy
Mesoblast, Ltd.

Not yet recruiting

Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Pain (HyaluronicAcid)

Degenerative Disc Disease
Afyonkarahisar Health Sciences University

Not yet recruiting

Clinical Success of Stainless Steel Crowns Applied Using Different Cements

Dental Enamel Hypomineralization

Turkey
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio

Not yet recruiting

Clinical-functional Effects of Bariatric Surgery on the Musculoskeletal System in Relation to Bone Turnover.

Bariatric Surgery Candidate
Johns Hopkins University
University of Maryland, Baltimore; McMaster University; Orthopaedic Trauma Association and other collaborators

Not yet recruiting

Accelerated Flap Coverage in Severe Lower Extremity Trauma (FLAP ATTACK)

Open Tibia Fracture | Extremity Fracture Lower | Open Dislocation of Ankle | Extremity Injuries Lower
Peking University People's Hospital

Not yet recruiting

Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors

Myelodysplastic Syndromes | Acute Leukemia | Severe Aplastic Anemia
Peking University Third Hospital

Recruiting

Multi-center Study on Comprehensive Diagnosis and Treatment of Lower Limb Bone Defect Based on Three-dimensional Printing Technology

Bone Defects

China
Göteborg University
King's College London; Charite University, Berlin, Germany; Geistlich Pharma AG; Queen Mary University of London and other collaborators

Not yet recruiting

Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects

Periodontitis | Furcation Defects

Sweden
Sohag University

Not yet recruiting

Comparative Study of Intravenous Labetalol Versus Intravenous Nitroglycerin Versus Sublingual Nifedipine

Severe Preeclampsia
Erasmus Medical Center

Not yet recruiting

Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With a Severe CHD (LbH)

Congenital Heart Disease | Executive Dysfunction | Attention Disorder

Netherlands
University Hospital, Antwerp
University Hospital, Ghent

Recruiting

Genome-wide Epistasis for Cardiovascular Severity in Marfan Study (GEMS)

Marfan Syndrome | FBN1 Mutation

Belgium
Institute of Hematology & Blood Diseases Hospital...

Recruiting

Rituximab for Serious Aplastic Anemia With Platelet Transfusion Refractoriness

Platelet Transfusion Refractoriness | Severe Aplastic Anemia

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

Efficacy of Bioceramic Materials for Bone Defects Repair

Osteo Arthritis Knee | Bone Loss | Bone Injury | Bone Fracture | Cartilage Degeneration | Bone Lesion

China
Amgen

Recruiting

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

Sjögren's Syndrome (SS)

United States
Al-Azhar University

Not yet recruiting

Combined Procedures in the Treatment of Severe Acne Scars

Atrophic Acne Scar
Episurf Medical Inc.

Recruiting

Clinical Investigation on the Outcome of Episealer Talus Post-operation for Treatment of Focal Osteochondral Defects

Osteochondral Defect

Germany, Sweden
Guangdong Provincial People's Hospital

Recruiting

Efficacy of Triple-Combination Therapy in Severe PAH-CHD

Pulmonary Arterial Hypertension | Congenital Heart Disease

China
Oluwasegun Aremu
Orthopaedic Trauma Association

Not yet recruiting

External Fixator or Antibiotic-coated Plate in Severe Open Long Bone Fractures

Fracture Related Infection

Nigeria
GreenBone Ortho S.p.A.

Recruiting

OSsIRIS Study - A Post-market Clinical Follow-up Investigation. (OSsIRIS)

Surgically Created Bone Defects or Bone Defects/Voids Resulting From Traumatic Injury

United Kingdom, Germany
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial) (VALUE)

High Blood Pressure | Coarctation of Aorta

United States
Kafrelsheikh University

Recruiting

Artificial Intelligence/Computer Guided Ridge Splitting for Treating Horizontal Ridge Defects

Alveolar Bone Resorption | Dental Implant Failure Nos

Egypt
Children's Hospital Medical Center, Cincinnati

Recruiting

Capturing Physiologic Autonomic Data From Clinically Indicated Magnetic Resonance Imaging Scans in Children (CMRI)

Cardiac Anomaly | Pectus Excavatum

United States
Amgen

Recruiting

A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

Sjogren's Syndrome

Israel, Chile, United States, Argentina, Canada, Japan, Korea, Republic of
Studio Dentistico Associato Sivolella

Recruiting

"Tunnel" Flap vs Trapezoidal Flap for Lateral Sinus Lift

Severe Atrophy of the Edentulous Maxilla

Italy
University Hospital, Lille

Not yet recruiting

Severe Congenital Hemostatic Defects, Cerebral MIcrobleeds and COGnition (HEMICOG)

Cerebral Microbleeds, Congenital Haemophilia, Congenital Von Willebrand Disease
Stanford University
Boston Children's Hospital; Duke University

Not yet recruiting

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

Heart Failure | Cardiomyopathies | Congenital Heart Disease | Cardiogenic Shock

United States
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Role of Vitamin D in Prevention of Dengue Haemorrhagic Fever and Dengue Shock Syndrome

Dengue Fever

Bangladesh
The Dental Hospital of Zhejiang University School...

Recruiting

A Study of Early Loading of Implants in the Maxillary Anterior Region With Alveolar Bone Defects

Dental Implant

China
Peking University People's Hospital

Recruiting

The Optimization of Conditioning Regimen for HLA Matched HSCT in SAA

Severe Aplastic Anemia

China
University Hospital of Ferrara

Recruiting

Analysis of Calcium Score of Severe Aortic Stenosis in Patients With and Without Cardiac Amyloidosis (CAUSATIVE Study) (CAUSATIVE)

Aortic Stenosis, Severe | Amyloidosis Cardiac

Italy
Cairo University

Recruiting

Evaluation of Autogenous Demineralized Dentin Graft Vs Autogenous Bone Graft in Management of Intrabony Defects

Intrabony Periodontal Defect

Egypt
Anhui Provincial Hospital

Recruiting

Conditioning Regimen Containing Low Dose ATG for The Treatment of Acquired SAA Receiving sUCBT

Severe Aplastic Anemia

China
Mansoura University

Recruiting

Subperiosteal Implants Constructed With Digital Technology

Alveolar Bone Loss

Egypt

Search clinical trials for: severe bone defects

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