Search clinical trials for: symptomatic carriers

Total 1827 results

Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Identification of Clinically Significant Markers of ATTRv in Pre-symptomatic Mutation Carriers.

Amyloidosis

Italy
Assistance Publique - Hôpitaux de Paris

Unknown

Natural History Characterization in Symptomatic and Asymptomatic Progranuline Gene Mutation Carriers (Predict-PGRN)

Frontotemporal Lobar Degeneration

France
University of California, San Francisco

Terminated

BIIB092 in Primary Tauopathies: CBS, nfvPPA, sMAPT, and TES (TauBasket)

Nonfluent Aphasia, Progressive | Primary Tauopathies | Corticobasal Degeneration Syndrome | Frontotemporal Lobar Degeneration With Tau Inclusions | MAPT Mutation Carriers, Symptomatic | Traumatic Encephalopathy Syndrome

United States
Novartis

Completed

A Community Setting Study of Malaria After Systematic Treatment of Symptomatic Carriers of P. Falciparum With COA566 (Coartem®)

Malaria

Burkina Faso
RSPR Pharma AB

Completed

CRD007 for the Treatment of Duchenne Muscular Dystrophy, Becker Muscular Dystrophy and Symptomatic Carriers

Duchenne Muscular Dystrophy | Becker Muscular Dystrophy

Sweden
Al-Azhar University

Not yet recruiting

Effect of Lower Limb Rotation on Clinical Outcomes After Arthroscopic Management in Patients With Symptomatic Femoroacetabular Impingement Syndrome

Femoro Acetabular Impingement
Shanghai University of Traditional Chinese Medicine
Shanghai Minimally Invasive Surgery Center

Not yet recruiting

Clinical Evaluation of Acupuncture Treatment on Alzheimer's Disease in APOE e4 Carriers and Non-Carriers

Cognitive Impairment | Alzheimer Disease

China
InnovHeart
MAXIS, LLC

Recruiting

Reduction of Mitral Regurgitation With the SATURN Trans-Septal Transcatheter Mitral Valve Replacement (TMVR) System in Patients With Severe Symptomatic Mitral Regurgitation (CASSINI-EU)

Heart Failure

Lithuania, Poland
Cytokinetics

Not yet recruiting

A Study to Evaluate the Effect of Aficamten in Pediatric Patients (Age 12 to <18 Years) With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM). (CEDAR-HCM)

Pediatric | Symptomatic Obstructive Hypertrophic Cardiomyopathy
Assistance Publique - Hôpitaux de Paris
Centre Leon Berard; Institut National de la Santé Et de la Recherche Médicale... and other collaborators

Not yet recruiting

Impact of Environmental Exposures on Tumor Risk in SDHx-mutation Carriers (PGLEXPO2)

Environmental Exposure | SDH Gene Mutation | SDH-Related Familial Paraganglioma | SDHx-Related Syndromes

France
Azienda Ospedaliero-Universitaria di Modena

Recruiting

Assessing Clinical Features and Outcome of Breast Cancer in PALB2 Mutation Carriers: the Palbreast Study (PALBREAST)

Breast Cancer

Italy
Medstar Health Research Institute

Not yet recruiting

Randomized Evaluation for Failed TAVR (REVIVE-TAVR)

Prosthesis Failure | Prosthetic Valve Malfunction | Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure
Sykehuset Telemark
Vestre Viken Hospital Trust; Oslo University Hospital; University Hospital of... and other collaborators

Not yet recruiting

Palliative Radiotherapy in Symptomatic Pelvic Soft Tissue Tumors (PALLSOFT)

Gynecologic Cancer | Gastrointestinal Cancer | Urologic Cancer
Cairo University

Not yet recruiting

The Effect of Photobiomodulation Using Low-Level Diode Laser Therapy on Postoperative Pain in Symptomatic Lower Molar Teeth With Irreversible Pulpitis and Apical Periodontitis; a Randomized Controlled Clinical Trial

Effect of Photobiomodulation Using Diode Laser
DiaSorin Molecular LLC

Not yet recruiting

LIAISON NES Influenza (FLU) A/B, Respiratory Syncytial Virus (RSV), & Coronavirus Disease 2019 (COVID-19) in Symptomatic Patients in Australia

Coronavirus Disease 2019 | Influenza A | Respiratory Syncytial Virus (RSV) | Adenovirus | Influenza Type B | Enterovirus | Mycoplasma Pneumonia | Bordetella Parapertussis Infection | Chlamydia Pneumonia | Para Influenza | Bordetella Pertussis Infection, Respiratory

Australia
Phathom Pharmaceuticals, Inc.

Recruiting

A Study to Evaluate Vonoprazan Concentrations in Breast Milk of Healthy Lactating Women Receiving Vonoprazan 20 mg Once Daily

Helicobacter Pylori Infection | Heartburn | Erosive Esophagitis | Symptomatic Nonerosive Gasroesophageal Reflux Disease

United States
Gene Solutions
University of Medicine and Pharmacy at Ho Chi Minh City

Recruiting

Clinical Validation of an MCED Test in Symptomatic Populations (K-ACCELERATE) (K-ACCELERATE)

Cancer, Breast | Cancer, Lung | Cancer Colon | Cancer, Gastric | Cancer, Liver

Vietnam
Aswan University

Recruiting

Fentanyl Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Spinal Anesthesia ; Peritoneal Symptomatic Effects

Dexmedetomidine | Fentanyl

Egypt
University Hospital, Bonn

Not yet recruiting

Placebo Optimization of the Presurgical Long-term Video-EEG Monitoring (OPERA)

Symptomatic Epilepsy

Germany
University of Minnesota

Recruiting

Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients

Surgical Site Infections | Healthcare Associated Infections | Staphylococcus Aureus Colonization

United States
University of Leicester
University Hospitals, Leicester

Not yet recruiting

Cognitive Impairment and Cerebral Haemodynamics in Individuals With Symptomatic Peripheral Arterial Disease (CInCH PAD)

Peripheral Arterial Disease | Cognitive Impairment

United Kingdom
Alnylam Pharmaceuticals

Recruiting

Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy

Hereditary Amyloidosis, Transthyretin-Related | Asymptomatic Carrier State

France
Jasper Therapeutics, Inc.

Recruiting

A Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients With Chronic Inducible Urticaria (CIndU) Who Remain Symptomatic Despite Treatment With H1- Antihistamines (SPOTLIGHT)

Chronic Inducible Urticaria

Germany
Regeneron Pharmaceuticals

Not yet recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

Amyotrophic Lateral Sclerosis (ALS) | Mutation in the Superoxide Dismutase-1 (SOD1) Gene
Fondazione IRCCS Policlinico San Matteo di Pavia

Recruiting

Potential Protective Role of SGLT-2 Inhibitors for Chemotherapy-induced Cardiotoxicity (PROTECT)

Breast Cancer

Italy
Anhui Medical University

Recruiting

Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study

Cognitive Impairment | Intracranial Atherosclerosis | Cerebrovascular Event

China
Prime Foundation

Recruiting

Comparison of Anesthetic Efficacy of Mental Nerve Block Versus Inferior Alveolar Nerve Block in Mandibular Anterior Teeth and Premolars in Symptomatic Irreversible Pulpitis

Symptomatic Irreversible Pulpitis

Pakistan
First Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

Efficacy of Butylphthalide on Symptomatic Atherosclerotic Stenosis in Middle Cerebral Artery (SICAS)

Ischemic Stroke, Acute | Intracranial Atherosclerosis

China
Heart Rhythm Clinical and Research Solutions, LLC
Biosense Webster, Inc.

Recruiting

The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation. (QDOT PAS)

Paroxysmal Atrial Fibrillation

United States
Beijing Tiantan Hospital

Not yet recruiting

Tirofiban for Patients With intraCranial Artery Stenosis and High-risk Acute Non-disabling Cerebrovascular Events(CHANCE-4）

TIA | Ischemic Stroke, Acute | Symptomatic Intracranial Artery Stenosis

China
Avantec Vascular
Bright Research Partners; Yale Cardiovascular Research Group

Recruiting

The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial) (GREAT)

Peripheral Arterial Disease

United States
University of Maryland, Baltimore
Inari Medical

Not yet recruiting

Large-Bore Mechanic Thrombectomy for the Treatment of Symptomatic Portomesenteric Vein Thrombosis

Thrombosis | Thrombectomy | Portal Vein
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Adipose Tissue and Symptomatic Gonarthrosis (TAGS)

Obesity | Gonarthrosis

France
Zhujiang Hospital

Not yet recruiting

Effectiveness of Atorvastatin in Preventing Cerebrovascular Events After Flow Diverter Implantation

Efficacy Endpoint: no New Cerebrovascular Adverse Events Within 1 Year | Safety Endpoint: no New Moderate or Serious Adverse Events Within 1 Year | All-cause Mortality Events (Within 1 Year) | Incident Ischemic Stroke Events (Within 1 Year) | New Hemorrhagic Stroke Events (Within 1 Year) | New... and other conditions
Xuanwu Hospital, Beijing

Recruiting

Revascularization for Symptomatic Non-acute Carotid Artery Occlusion (RESCO)

Non-acute Carotid Artery Occlusion

China
October 6 University

Not yet recruiting

Effect of Different Modalities of Cryotherapy on Post-Operative Pain in Patients With Symptomatic Irreversible Pulpitis

Endodontic Disease | Endodontically Treated Teeth

Egypt
Lebanese University
Haykel Hospital

Recruiting

Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA (PTST_PALBEVA)

Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Chemotherapy | Solid Tumor | Immunotherapy | Targeted Therapy | Precision Therapy

Lebanon
A.O.U. Città della Salute e della Scienza

Recruiting

Effectiveness of a Single Dose of Betamethasone in Children With Symptomatic Adenovirus Infection (Adeno-beta)

Adenovirus

Italy
Servier Affaires Médicales

Recruiting

Effectiveness of a Combination of Trimetazidine With One Hemodynamic Agent in Patients Recently Diagnosed With Stable Angina and Still Symptomatic Despite First Line Hemodynamic Therapy

Stable Angina

Romania
Cairo University
Egyptian Russian University

Not yet recruiting

The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain

Symptomatic Irreversible Pulpitis
Eli Lilly and Company

Not yet recruiting

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

Alzheimer Disease

United States, United Kingdom, Japan
Pfizer

Not yet recruiting

A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis (EFFECT-UC)

Colitis, Ulcerative

United Kingdom, Germany
Assiut University

Not yet recruiting

EUS Guided Drainage of Post Pancreatitis Pancreatic Fluid Collection

Pancreas Pseudocyst
Biosense Webster, Inc.

Recruiting

A Study of the THERMOCOOL SMARTTOUCH Surround Flow (SF) Catheter With the TRUPULSE Generator for Treatment of Drug Refractory Symptomatic PAFOUS (PulseSmart)

Atrial Fibrillation

Australia, Canada
Universitaire Ziekenhuizen KU Leuven

Recruiting

Biomechanical Investigation of Symptomatic FAI and Two Groups of Asymptomatic Controls (CAM-FAI adult)

Femoroacetabular Impingement

Belgium
Fondation Ophtalmologique Adolphe de Rothschild

Not yet recruiting

Efficacy and Safety of Anti-angiogenic Therapy With IV Bevacizumab in Patients With Symptomatic Cerebral Arteriovenous Malformations (BevacizuMAV)

Cerebral AV Malformation
University of Rochester

Not yet recruiting

Thoracic Radiotherapy for Patients With Metastatic (Stage IV) Non-Small Cell Lung Cancer at High Risk of Symptomatic Progression Within the Thorax (DRO2301)

Radiotherapy | Stage 4 NSCLC
ZetrOZ, Inc.

Not yet recruiting

Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis

Arthritis | Osteo Arthritis Knee

United States
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United States, Australia, Canada, France, Germany, Ireland, Italy, Spain, United Kingdom
Ascension Health
Medtronic

Recruiting

Physiologic Pacing for Symptomatic First-Degree Heart Block

Symptomatic First-degree Heart Block

United States

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