Search clinical trials for: vaginal ring administration

Total 11740 results

Galeno Desenvolvimento de Pesquisas Clínicas
SocraTec R&D GmbH

Completed

Pharmacokinetics and Pharmacodynamics of 3 Dosages of Estriol After Continuous Vaginal Administration for 21 Days

Menopause

Brazil
Population Council

Completed

An Open-label Study to Evaluate the Effects of Concurrent Administration of Vaginal Antimycotic Medication Miconazole Nitrate on the Pharmacokinetics of Nestorone and Ethinyl Estradiol Delivered by a Contraceptive Vaginal Ring in Normal Ovulating Women

Antifungal Drug Adverse Reaction

United States
Universidad de Guanajuato
Antisepsia Central

Completed

Residual Effect of Chlorhexidine-alcohol Compared to Triclosan-alcohol

Infectious Diseases

Mexico
Erzincan Military Hospital

Not yet recruiting

Evaluating the Efficacy and Safety of Preoperative Administration of Duloxetine for Pain Management in Women Undergoing Vaginal Hysterectomy.

Postoperative Pain | Vaginal Hysterectomy
University of Connecticut
Department of Health and Human Services (DHHS) Administration for Community... and other collaborators

Not yet recruiting

Evaluating an Enhanced Home-delivered Meal Program on Older Adults' Health and Well-being

Quality of Life | Food Insecurity | Loneliness | Diet, Healthy
Mayo Clinic
National Cancer Institute (NCI)

Not yet recruiting

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy of Intraoperative Use of 20% Albumin Combined With Ringer Lactate Versus Ringer Lactate During Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy (ALBUCHIP)

Postoperative Complications | Peritoneal Neoplasms | Fluid Therapy | Hyperthermic Intraperitoneal Chemotherapy | Intraoperative Care
Ira Winer

Recruiting

ASk Questions in GYnecologic Oncology (ASQ-GYO) (ASQ-GYO)

Cervical Cancer | Ovarian Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Gestational Trophoblastic Disease

United States
Roswell Park Cancer Institute

Not yet recruiting

Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction

Malignant Solid Neoplasm

United States
Africa Health Research Institute

Recruiting

Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCT (LAPIS)

HIV Infections

South Africa
University of Pittsburgh
United States Agency for International Development (USAID); Oak Crest Institute...

Recruiting

Trial to Assess Acceptability and Safety of Two Placebo Intravaginal Rings (MATRIX-003)

Safety | Acceptability

United States, South Africa, Zimbabwe
Evestra Inc.

Recruiting

Comparative Bioavailability Study of Ethinyl Estradiol/Etonogestrel Vaginal Ring

Contraception | Female | Healthy Women

Canada
ART Fertility Clinics LLC

Recruiting

Optimal Timing of Euploid Day 6 Blastocyst Transfer in Frozen HRT Cycles, Day 6 or Day 7 of Progesterone Administration.

Infertility | Fertility Issues | Infertility, Female

United Arab Emirates
Ohio State University Comprehensive Cancer Center

Recruiting

Evaluation of Vaginal Microbiome as a Biomarker for the Improvement of Vaginal Health in Women With Breast Cancer, ARISE Study

Breast Neoplasms

United States
FHI 360
United States Agency for International Development (USAID); Jhpiego; Wits Reproductive... and other collaborators

Recruiting

The CATALYST Study

HIV Prevention

Kenya, Lesotho, South Africa, Uganda, Zimbabwe
Gemelli Molise Hospital
Opera CRO, a TIGERMED Group Company

Not yet recruiting

Tocopherol Acetate Vaginal Administration in Pre-peri and Postmenopausal Women

Pre- Peri, and Postmenopausal Women
Freya Biosciences ApS

Recruiting

FB101 Intervention in Women Screened to Have Vaginal Dysbiosis (Dyscover-3) (Dyscover-3)

Vaginal Flora Imbalance

Ireland
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

e-Health Intervention (Day-by-Day) for the Management of Fear of Progression in Women With Stage III or IV Gynecologic Cancer: A Pilot Study

Stage III Uterine Corpus Cancer AJCC v8 | Stage IV Uterine Corpus Cancer AJCC v8 | Malignant Female Reproductive System Neoplasm | Stage III Cervical Cancer AJCC v8 | Stage IV Cervical Cancer AJCC v8 | Stage IV Vulvar Cancer AJCC v8 | Stage III Ovarian Cancer AJCC v8 | Stage IV Ovarian Cancer AJCC... and other conditions

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

Stage I Uterine Corpus Cancer AJCC v8

United States
AtoGen Co. Ltd
ATOGEN AUSTRALIA PTY LTD

Recruiting

Safety, Tolerability, and Acceptability Study of Intravaginal Administration of LABTHERA-001 Capsules in Healthy Women

Bacterial Infections | Vaginal Disease | Vaginitis | Infection, Bacterial | Bacterial Vaginosis

Australia
Assistance Publique - Hôpitaux de Paris

Recruiting

Development and Clinical Evaluation of an Innovative Medical Device to Predict Preterm Birth (PrediMAP) (PrediMAP)

Preterm Labor

France
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma

United States
Seoul National University Hospital

Recruiting

Intraoperative Normal Saline Administration and Acute Kidney Injury in Patients Undergoing Liver Transplantation

Liver Cirrhosis | Liver Transplant; Complications | End Stage Liver DIsease

Korea, Republic of
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Not yet recruiting

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions
Maastricht University Medical Center
Zuyderland Medical Centre

Recruiting

The Effect of Medical Grade Honey Formulation (L-Mesitran) Administration on Recurrent Vulvovaginal Candidiasis Symptoms

Candidiasis, Vulvovaginal | Recurrent Candidiasis of Vagina

Netherlands
Al-Azhar University

Not yet recruiting

Uterine Artery Doppler Changes After Vaginal Administration of Isosorbide Mononitrate In Patients With URPL

Recurrent Pregnancy Loss
National Taiwan University Hospital

Recruiting

Multimodal GA for Lumbar Spine Surgery

Lumbar Spine Fusion Surgery

Taiwan
National Cancer Institute (NCI)

Recruiting

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Mucosal Melanoma | Anal Melanoma | Bladder Melanoma | Cervical Melanoma | Esophageal Melanoma | Gallbladder Melanoma | Mucosal Melanoma of the Head and Neck | Mucosal Melanoma of the Urinary System | Oral Cavity Mucosal Melanoma | Penile Mucosal Melanoma | Rectal Melanoma | Recurrent Mucosal Melanoma | Sinonasal... and other conditions

United States, Canada
International Partnership for Microbicides, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel

Bleeding | Pharmacokinetics | Safety Issues

United States
Andrea Roe, MD, MPH

Recruiting

Does Vaginal Delivery of Combined Hormonal Contraception Affect the Risk of Metabolic Syndrome in Overweight/Obese Women With PCOS (RING-PCOS)

Polycystic Ovary Syndrome

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma

United States, Korea, Republic of
Columbia University
Johns Hopkins University; Northwell Health; Cornell University; Childress Institute...

Recruiting

Effect of Giving Reduced Fluid in Children After Trauma

Wounds and Injuries | Critical Illness | Fluid Therapy | General Surgery | Pediatrics

United States
UMC Utrecht
National University Hospital, Singapore; Berry Consultants; University of Pittsburgh... and other collaborators

Recruiting

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (REMAP-CAP)

Community-acquired Pneumonia, Influenza, COVID-19

United Kingdom, United States, Canada, Australia, Netherlands, Croatia, Germany, Belgium, New Zealand, Ireland, Spain, Japan, Hungary, Colombia, India, Nepal, Pakistan, Portugal, Romania, Saudi Arabia
American Society of Clinical Oncology
Bristol-Myers Squibb; Eli Lilly and Company; Bayer; Merck Sharp & Dohme LLC; Pfizer; AstraZene... and other collaborators

Recruiting

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer (TAPUR)

Lymphoma, Non-Hodgkin | Multiple Myeloma | Advanced Solid Tumors

United States
Polly A. Niravath, MD

Recruiting

REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy (REVIVE)

Breast Cancer | Estrogen Receptor Positive Breast Cancer

United States
Northwestern University
National Cancer Institute (NCI)

Recruiting

Specimen and Data Study for Ovarian Cancer Early Detection and Prevention

Sarcoma | Cervical Cancer | Ovarian Cancer | Fallopian Tube Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Hereditary Breast/Ovarian Cancer (brca1, brca2) | Uterine Leiomyomata

United States
National Cancer Institute (NCI)

Active, not recruiting

Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

Lynch Syndrome | Colon Mucinous Adenocarcinoma | Colon Signet Ring Cell Adenocarcinoma | Stage IIA Colon Cancer AJCC v7 | Stage IIB Colon Cancer AJCC v7 | Stage IIC Colon Cancer AJCC v7

United States, Canada, Puerto Rico, Peru, South Africa
Organon and Co

Completed

A Dose-Finding Study to Evaluate Ovarian Function and Vaginal Bleeding in Next Generation Rings (P06109/MK-8175A/MK-8342B-012)

Contraception
Organon and Co

Completed

A Study to Evaluate the Effect of Contraceptive Vaginal Rings on Primary Dysmenorrhea (P08257/MK-8175A/MK-8342B-057)

Dysmenorrhea
Organon and Co

Terminated

Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in the Treatment of Women With Primary Dysmenorrhea (MK-8342B-060)

Dysmenorrhea
Organon and Co

Terminated

Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in Women With Primary Dysmenorrhea (With Optional Extension) (MK-8342B-059)

Moderate to Severe Primary Dysmenorrhea
Organon and Co

Completed

Study of the Use of a Contraceptive Vaginal Ring (NuvaRing) in Normal Daily Practice in Indian Women (P07733)

Contraception
Organon and Co

Completed

A Study to Evaluate the Effectiveness of NuvaRing® to Prevent Pregnancies in Chinese Women (P06450)

Contraception
Organon and Co

Terminated

Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring and Levonorgestrel-Ethinyl Estradiol Combined Oral Contraceptive in Adult Women at Risk for Pregnancy (MK-8342B-062)

Contraception

South Africa, Austria, Costa Rica, Denmark, Finland, Germany, Hungary, Italy, Mexico, Netherlands, Norway, Peru, Poland, Sweden
Organon and Co

Terminated

Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring in Women at Risk for Pregnancy (MK-8342B-061)

Contraception
Organon and Co

Completed

Performance and Safety of Vaginal Ring Applicator in Healthy Females (MK-8342A-063)

Contraception: Optional Applicator for Insertion of Vaginal Ring
Ohio State University Comprehensive Cancer Center

Completed

Sexual Health Counseling Intervention During Radiation Therapy in Improving Quality of Life for Women With Gynecologic Cancer

Stage III Uterine Corpus Cancer AJCC v8 | Stage IVA Uterine Corpus Cancer AJCC v8 | Malignant Female Reproductive System Neoplasm | Stage I Cervical Cancer AJCC v8 | Stage IA Cervical Cancer AJCC v8 | Stage IA1 Cervical Cancer AJCC v8 | Stage IA2 Cervical Cancer AJCC v8 | Stage IB Cervical Cancer... and other conditions

United States
NRG Oncology
National Cancer Institute (NCI); Canadian Cancer Trials Group

Suspended

Tailoring Therapy in Post-surgical Patients With Low-risk Endometrial Cancer

Stage I Uterine Corpus Endometrial Stromal Sarcoma AJCC v8 | Stage II Uterine Corpus Endometrial Stromal Sarcoma AJCC v8 | Stage III Uterine Corpus Endometrial Stromal Sarcoma AJCC v8

United States
Penn State University
Purdue University

Active, not recruiting

Assessing the Impact of Contraceptives on Bone Health Using 41Ca

Other Disorders of Bone Development and Growth

United States
Fondazione Policlinico Universitario Agostino Gemelli...
Massimo Antonelli; Cristina Dominedò; Marco Rossi; Rossano Festa; Nicoletta Filetici and other collaborators

Completed

Effect of Crystalloids With Different SID on pH, and Urinary Electrolytes During General Anesthesia (CRYSID)

Acid-Base Imbalance | SID

Italy

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