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Bioinformatician - 12 months contract (client-dedicated)

Pharmaceutical Product Development (PPD)

Rixensart, Belgium

Job Description

At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.

Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to use the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.

This role will work fully on-site with our client in Rixensart, Belgium.

Key Responsibilities

As a Bioinformatician you will work within the Molecular Biology Group to support the analysis of multi-omics data for Preclinical projects. This role will involve:

  • Generation of analytical pipeline for data integration
  • Data analysis and integration
  • Provide Bioinformatic support during antigen discovery efforts
  • Develop and implement algorithms for integrating diverse data types, such as productivity measures, affinity measurements, binding profiles and the analysis od cellular iterations
  • Creating scripts or workflows that merge the information coherently, enabling a comprehensive view of antibody characteristics
  • Develop methods for integrating data from different omics modalities, such as single-cell RNA sequencing, BCR/TCR sequencing, and spatial transcriptomics.
  • Investigate correlations between clonal diversity and gene expression patterns
  • Consider statistical and computational methods to harmonize the data
  • Creating/developing custom scripts or workflows
  • Participate to weekly lab meetings

Qualifications/ Experience

  • Ph.D. in Bioinformatics, Computational Biology, Biostatistics, or a related field.
  • Master’s degree may be considered based on previous experience.
  • Strong background in computational biology and bioinformatics methodologies with focus on multi-omics data analysis.
  • Proficiency in programming languages such as Python and R.
  • Knowledge of analysis and integration of multi-omics data, including single-cell transcriptomics, BCR/TCR sequencing.
  • Knowledge of statistical methods for high-dimensional data analysis.
  • Additional knowledge of structural biology and software platforms like MOE, or any equivalent software (Rosetta / Schrödinger) is a plus.
  • Result-oriented, rigorous and structured.
  • Fluency in English is essential , Fluency in French is also highly desirable

Our Mission is to enable our customers to make the world healthier, cleaner and safer. Watch as our colleagues explain 5 reasons to work with us. As one team of 100,000+ colleagues, we share a common set of values - Integrity, Intensity, Innovation and Involvement - working together to accelerate research, solve complex scientific challenges, drive technological innovation and support patients in need. #StartYourStory with PPD, part of Thermo Fisher Scientific, where diverse experiences, backgrounds and perspectives are valued.

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

Job posted: 2024-03-08

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