Motion Sickness Severity and Sensorimotor Performance
23. juni 2026 opdateret af: Yunus Emre Tutuneken, Istinye University
The Relationship of Balance, Proprioception, Coordination, and Reaction Time Measurements With Motion Sickness Severity in Individuals With Motion Sickness: A Cross-Sectional Study
Background: Motion sickness (MS) is a common syndrome characterized by autonomic and behavioral symptoms, such as nausea and dizziness, resulting from exposure to motion stimuli.
Its pathophysiology is closely linked to sensory conflict and postural instability theories.
While previous studies suggest that postural control, proprioception, and reaction times are affected in individuals susceptible to MS, there is a lack of comprehensive, comparative research evaluating all these parameters concurrently within the same cohort using standardized methods.
Objective: This study aims to systematically measure balance, proprioceptive sensitivity, coordination, and reaction time parameters, and quantitatively analyze their relationship with motion sickness severity.
Methodology: In this prospective, cross-sectional study, at least 41 participants aged 18-40 with motion sickness will be recruited.
Participants will undergo motion sickness susceptibility and severity grading using the Motion Sickness Susceptibility Questionnaire Short Form (MSSQ-SF) and the Graybiel Scale.
Objective assessments will include static and dynamic balance testing (ProKin®), knee joint position sense (Clinometer app), manual dexterity and dynamic balance coordination (Nine-Hole Peg Test, Tandem Walk, Romberg Test), and upper/lower extremity reaction time measurements (BlazePod system).
Studieoversigt
Status
Ikke rekrutterer endnu
Betingelser
Intervention / Behandling
Undersøgelsestype
Observationel
Tilmelding (Anslået)
41
Deltagelseskriterier
Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.
Berettigelseskriterier
Aldre berettiget til at studere
- Voksen
Tager imod sunde frivillige
Ingen
Prøveudtagningsmetode
Ikke-sandsynlighedsprøve
Studiebefolkning
The study population consists of adult individuals aged between 18 and 40 years who exhibit susceptibility to motion sickness.
Beskrivelse
Inclusion Criteria:
- Individuals aged between 18 and 40 years.
- Diagnosed with motion sickness according to the Motion Sickness -Susceptibility Questionnaire Short Form (MSSQ-SF).
- Normal hearing acuity.
- No history of acute or chronic vestibular disease, other than motion sickness.
- Normal or corrected-to-normal vision.
- Adequate physical capability to fully perform the measurement protocols, including balance, proprioception, coordination, and reaction time tests.
Exclusion Criteria:
- Presence of any physical or orthopedic problem that could interfere with testing.
- History of acute or chronic instability, unsteadiness, or vertigo.
- Severe visual impairment.
- History of prior ear surgery.
- Presence of any neurological condition or disorder.
- History of migraines.
- Current use of medications that could affect balance or vestibular function (e.g., vestibular suppressants, sedatives).
- Use of alcohol or psychoactive substances within the last 48 hours prior to testing.
Studieplan
Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Static Balance
Tidsramme: 1 hour
|
Evaluated objectively using the ProKin® computerized balance system.
Participants stand on the platform under conditions: double-leg with eyes open.
|
1 hour
|
|
Dynamic Balance Performance
Tidsramme: 1 hour
|
Evaluated using the ProKin® system.
|
1 hour
|
|
Motion Sickness Severity (Graybiel Score)
Tidsramme: 1 hour
|
Used to grade the clinical severity of acute motion sickness symptoms (including nausea, cold sweating, increased salivation, and dizziness) following a randomized chair-rotation provocation protocol.
0 (Minimum) to 50 points (Maximum).
Higher scores indicate greater symptom severity, representing a worse clinical outcome (scores of 16 or above designate frank sickness).
|
1 hour
|
Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Knee Joint Proprioception
Tidsramme: 1 hour
|
Evaluated in supine and prone positions, targeting knee angles of 15°, 30°, 60°, and 90° using the Clinometer digital inclinometer smartphone application.
|
1 hour
|
|
Nine-Hole Peg Test (9HPT) Completion Time
Tidsramme: 1 hour
|
Used to assess upper extremity dexterity and fine motor coordination.
Participants place nine pegs into the holes one by one and then remove them as quickly as possible.
|
1 hour
|
|
Tandem Walk Test Error Count
Tidsramme: 1 hour
|
Participants walk barefoot along a straight line for 10 steps, placing the heel of one foot directly against the toe of the other foot with arms relaxed at their sides.
|
1 hour
|
|
Visual Reaction Time
Tidsramme: 1 hour
|
Evaluated using the mobile application-based BlazePod.
|
1 hour
|
Samarbejdspartnere og efterforskere
Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.
Sponsor
Datoer for undersøgelser
Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.
Studer store datoer
Studiestart (Anslået)
1. juni 2026
Primær færdiggørelse (Anslået)
2. august 2026
Studieafslutning (Anslået)
5. august 2026
Datoer for studieregistrering
Først indsendt
26. maj 2026
Først indsendt, der opfyldte QC-kriterier
26. maj 2026
Først opslået (Faktiske)
2. juni 2026
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
26. juni 2026
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
23. juni 2026
Sidst verificeret
1. juni 2026
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- 25
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