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Effect of Marjoram, Vetiver, and Lavender Oil in the Treatment of Bruxism

30. juni 2026 opdateret af: SULTAN UZUN, Necmettin Erbakan University
The aim of this study was to investigate the possible effects of the use of lavender, marjoram and vetiver oil via inhalation and/or massage application on the treatment of bruxism.

Studieoversigt

Detaljeret beskrivelse

Bruxism is a repetitive jaw muscle activity characterized by clenching or grinding of the teeth and/or bracing or thrusting of the mandible. Due to increasing evidence suggesting that it may serve a physiological purpose, bruxism has been defined as jaw muscle activity that may occur during sleep and/or wakefulness.

Various methods have been proposed for the treatment of bruxism. These treatment approaches include pharmacological treatments (such as muscle relaxants and clonazepam), orthopedic treatments (such as stabilization splints and rigid stabilization appliances), needling treatments (including acupuncture, botulinum toxin type A, and dry needling), physical and behavioral approaches (such as relaxation training, stress management, biofeedback, and sleep hygiene instructions), manual treatments including exercises (trigger point therapy, soft tissue techniques, exercises, postural corrections, joint mobilizations, and cervical spine treatment), and other physical therapy modalities (including low-level laser therapy, therapeutic ultrasound, and short-wave diathermy).

Manual therapy, therapeutic exercise, and their combination have been shown to effectively reduce pain and improve mandibular function. Massage therapy, which activates the pain-gate mechanism, is an effective treatment option for pain relief. It also stimulates the parasympathetic nervous system and helps restore muscle length and flexibility. In addition, massage therapy improves local blood circulation and promotes the production of endogenous opioids, leading to relaxing effects and reduced pain perception. These effects are of particular interest in the management of bruxism; however, this treatment approach has not been adequately investigated despite its promising results.

Massage therapy can be combined with aromatherapy, one of the most commonly used complementary therapy methods. Its therapeutic effects are based on stimulation of the olfactory system and absorption of active molecules through the skin. Various studies have investigated the analgesic effects of aromatherapy massage using lavender essential oil. Lavandula angustifolia is a well-known medicinal and aromatic plant with anti-inflammatory and analgesic properties. In addition, it has antiseptic, soothing, circulation-stimulating, and cell-regenerating effects. Lavender oil has been reported to reduce pain in patients with various conditions, including neuropathic pain, rheumatoid arthritis, burns, and cancer-related pain. Apart from lavender oil, marjoram oil may contribute to pain control and anxiety reduction, while vetiver oil is known for its sedative effects. However, the effects of aromatherapy massage using these essential oils have not been adequately investigated in patients with bruxism.

The aim of this study is to evaluate the effects of lavender, marjoram, and vetiver essential oils administered through aromatherapy massage in patients with bruxism. Objective outcomes will be assessed through ultrasonographic evaluation of the masseter muscle, while subjective outcomes will be evaluated using patient-reported questionnaires. The findings of this study may contribute to the development of complementary treatment approaches for the management of bruxism.

Undersøgelsestype

Interventionel

Tilmelding (Anslået)

64

Fase

  • Ikke anvendelig

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

    • Merkez
      • Bilecik, Merkez, Tyrkiet (Türkiye), 11100
        • Bilecik Seyh Edebali University

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Voksen

Tager imod sunde frivillige

Ja

Beskrivelse

Inclusion Criteria:

  • • Patients between 18-25

    • Patients with full dentition including 2nd molars
    • Patients without facial asymmetry
    • Patients without history of sensitivity or allergy to plants
    • Patients without olfactory disorders

Exclusion Criteria:

  • • Patients with systemic (asthma history) and/or neuromuscular disease

    • Patients with orofacial pain not caused by bruxism
    • Temporomandibular joint (TMJ) surgery or injection history
    • Use of any medical drug affecting the muscular system
    • Patients with developmental deformity or surgery history in the maxillofacial region (facial trauma history, resection history, etc.)
    • TMJ pathologies (major condylar changes seen on panoramic radiograph)
    • Radiotherapy and/or chemotherapy history
    • Ongoing orthodontic treatment
    • Removable prosthesis use
    • Inflammatory connective tissue diseases
    • Pregnancy
    • Obstructive sleep apnea
    • Local skin infection over the myofascial area
    • Reluctance to take responsibility for the work

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Behandling
  • Tildeling: Randomiseret
  • Interventionel model: Parallel tildeling
  • Maskning: Ingen (Åben etiket)

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Placebo komparator: Control Group
Participants receive carrier oil (sesame oil) administered through inhalation and extraoral massage following the same protocol as the intervention group. Outcomes are evaluated using ultrasonographic measurements and patient-reported questionnaires.
Participants receive carrier oil (sesame oil) administered through inhalation and extraoral massage according to the same protocol used in the intervention group.
Eksperimentel: Aromatherapy Group
Participants receive aromatherapy by inhalation twice daily and extraoral massage once daily throughout the study period. Outcomes are evaluated using ultrasonographic measurements and patient-reported questionnaires.
Participants receive aromatherapy using a proprietary essential oil blend (Lavender Lavandula angustifolia, Marjoram Origanum majorana, and Vetiver Vetiveria zizanioides; Art De Huile®, formulated by Hülya Kayhan). The blend is administered by inhalation twice daily and extraoral massage once daily throughout the study period.

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Change in Masseter Muscle Elasticity
Tidsramme: Baseline to Week 4
Assessment of changes in masseter muscle elasticity using shear-wave elastography measured by ultrasonography.
Baseline to Week 4
Change in Masseter Muscle Thickness
Tidsramme: Baseline to Week 4
Assessment of changes in masseter muscle thickness measured by ultrasonography.
Baseline to Week 4

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Change in Bruxism-Related Symptoms
Tidsramme: Baseline to Week 4
Assessment of changes in bruxism-related symptoms (jaw pain, headache, tooth sensitivity, fatigue, and perceived stress/anxiety) using the Visual Analog Scale (VAS). Each symptom is rated from 0 (no symptom) to 10 (worst imaginable symptom). Higher scores indicate more severe symptoms. A study-specific patient-reported questionnaire is also used to document the presence and characteristics of bruxism-related symptoms.
Baseline to Week 4
Patient Satisfaction With Treatment
Tidsramme: Week 4
Assessment of participant satisfaction with the intervention using a study-specific patient-reported questionnaire. Treatment satisfaction is rated on a 5-point Likert scale ranging from 1 (very dissatisfied) to 5 (very satisfied). Higher scores indicate greater treatment satisfaction.
Week 4

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

2. september 2024

Primær færdiggørelse (Anslået)

31. december 2026

Studieafslutning (Anslået)

31. januar 2027

Datoer for studieregistrering

Først indsendt

18. juni 2026

Først indsendt, der opfyldte QC-kriterier

18. juni 2026

Først opslået (Faktiske)

24. juni 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

2. juli 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

30. juni 2026

Sidst verificeret

1. juni 2026

Mere information

Begreber relateret til denne undersøgelse

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

INGEN

IPD-planbeskrivelse

Individual participant data (IPD) will not be made publicly available due to participant privacy considerations and institutional data protection policies.

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

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Ingen

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Ingen

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Kliniske forsøg med Carrier Oil (Sesame Oil)

3
Abonner