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Reliability and Validity of Three DT-TUG Protocols in MS

24. august 2026 opdateret af: Emel Taşvuran Horata, Afyonkarahisar Health Sciences University

Comparison of the Reliability and Convergent Validity of Three Dual-Task Timed Up and Go Protocols in People With Multiple Sclerosis

Dual-tasking is performing two different tasks at the same time. For example, singing while cooking. Everyday activities often involve dual-task. In many researches evaluating dual-task performance in individuals with MS, it has been reported that individuals with severe disability, in particular, exhibit greater effort than healthy individuals. This increase in motor and cognitive dual-task performance in individuals with Multiple Sclerosis (MS) is associated with an increased risk of falls. There is a need for standardized, valid, and reliable assessment tools to evaluate dual-task performance in MS. The purpose of this study is to examine and compare the validity and reliability of the dual-task Timed Up and Go test administered using three different protocols.

Studieoversigt

Status

Rekruttering

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Dual-tasking is performing two different tasks at the same time. For example, singing while cooking. Everyday activities often involve dual-task. In many researches evaluating dual-task performance in individuals with MS, it has been reported that individuals with severe disability, in particular, exhibit greater effort than healthy individuals. This increase in motor and cognitive dual-task performance in individuals with MS is associated with an increased risk of falls. There is a need for standardized, valid, and reliable assessment tools to evaluate dual-task performance in MS. The purpose of this study is to examine and compare the validity and reliability of the dual-task Timed Up and Go test (DTUG) administered using three different protocols. To this end, this study will evaluate the validity and reliability of the DTUGs-which consist of three subtasks: counting backward in threes, verbal fluency, and ball-carrying on a tray-and compare their clinical applicability relative to one another. For validity analyses, convergent validity will be assessed. For reliability analyses, intra- and inter-rater reliability will be assessed, and SEM and MDC values will be calculated. Additionally, Bland-Altman plots will be plotted for intra- and inter-rater agreement analyses.

Undersøgelsestype

Observationel

Tilmelding (Anslået)

40

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiekontakt

Undersøgelse Kontakt Backup

Studiesteder

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Voksen
  • Ældre voksen

Tager imod sunde frivillige

Ingen

Prøveudtagningsmetode

Ikke-sandsynlighedsprøve

Studiebefolkning

Participants will be recruited from among individuals who visit the outpatient clinic of the Department of Neurology at SANKO University.

Beskrivelse

Inclusion Criteria:

  • Having been diagnosed with MS according to the McDonald criteria revised in 2017,
  • Being between the ages of 18 and 65,
  • Having an Expanded Disability Status Scale (EDSS) score between 0 and 5.5,
  • Not requiring any assistive walking devices.

Exclusion Criteria:

  • Pregnancy;
  • Having experienced a relapse within the past three months;
  • The presence of another neurological condition in addition to MS;
  • The presence of a different disorder that could potentially affect gait parameters;
  • The presence of visual, auditory, perceptual, or cognitive impairments severe enough to interfere with the test administration

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Kohorter og interventioner

Gruppe / kohorte
Intervention / Behandling
Patients with Multiple Sclerosis
Patients with Multiple Sclerosis aged between 18-65 years
Andet: Intra-rater reliability analysis
For the intra-rater reliability analysis, three DTUG protocols will be evaluated at 7- to 10-day intervals.
Andet: Inter-rater reliability analysis
For the inter-rater reliability analysis, three DTUG protocols will be administered to the same patient by two different physical therapists.
Andet: Convergent validity
To assess convergent validity, the relationship between the measurements from the three DTUG protocols and the results of other balance and functional mobility tests will be examined.

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Dual-task Timed up and go test (DTUG)
Tidsramme: A single assessment will be administered to all participants at the end of the study. The assessment takes approximately 5 minutes.
The DTUG task will be evaluated in three different ways. The primary task will consist of the Timed Up and Go (TUG) test. The TUG test involves standing up from a chair, walking 3 meters, turning around, and sitting back down. While this test is being administered, secondary tasks will be performed simultaneously, and the time taken to complete the test will be recorded. The secondary tasks consist of a three-count backward counting task, verbal fluency, and a ball-carrying task on a tray.
A single assessment will be administered to all participants at the end of the study. The assessment takes approximately 5 minutes.

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Afyonkarahisar Health Sciences University

Efterforskere

  • Ledende efterforsker: Emel TAŞVURAN HORATA, PhD, Afyonkarahisar Health Sciences University
  • Studiestol: Hakan POLAT, PhD, Sanko University
  • Studiestol: Meltem UZUN, PhD, Sanko University
  • Studiestol: Suat EREL, PhD, Pamukkale University

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

16. marts 2026

Primær færdiggørelse (Anslået)

14. september 2026

Studieafslutning (Anslået)

14. september 2026

Datoer for studieregistrering

Først indsendt

24. august 2026

Først indsendt, der opfyldte QC-kriterier

24. august 2026

Først opslået (Faktiske)

27. august 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

27. august 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

24. august 2026

Sidst verificeret

1. august 2026

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • 2026/02-1

Plan for individuelle deltagerdata (IPD)

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UBESLUTET

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Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

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