Ambulatory continuous interscalene nerve blocks decrease the time to discharge readiness after total shoulder arthroplasty: a randomized, triple-masked, placebo-controlled study
Brian M Ilfeld, Krista Vandenborne, Pamela W Duncan, Daniel I Sessler, F Kayser Enneking, Jonathan J Shuster, Douglas W Theriaque, Terese L Chmielewski, Eugene H Spadoni, Thomas W Wright, Brian M Ilfeld, Krista Vandenborne, Pamela W Duncan, Daniel I Sessler, F Kayser Enneking, Jonathan J Shuster, Douglas W Theriaque, Terese L Chmielewski, Eugene H Spadoni, Thomas W Wright
Abstract
Background: A continuous interscalene nerve block (CISB) may be used to provide analgesia after shoulder arthroplasty. Therefore, inpatient stays may be shortened if CISB (1) provides adequate analgesia without intravenous opioids and (2) improves shoulder mobilization. This study investigated the relationship between ambulatory CISB and the time to reach three discharge criteria after shoulder arthroplasty.
Methods: Preoperatively, patients received a CISB. All patients received a perineural 0.2% ropivacaine infusion from surgery until 06:00 the following morning, at which time they were randomly assigned either to continue perineural ropivacaine or to switch to normal saline. The primary endpoint was the time from the end of surgery until three discharge criteria were attained (adequate analgesia, independence from intravenous analgesics, and tolerance to 50% of shoulder motion targets). Patients were discharged home as early as the afternoon after surgery with their CISB using a portable infusion pump.
Results: Patients receiving perineural ropivacaine (n = 16) attained all three discharge criteria in a median (10th-90th percentiles) of 21 (16-41) h, compared with 51 (37-90) h for those receiving perineural normal saline (n = 13, P < 0.001). Unlike patients receiving perineural ropivacaine, patients receiving perineural normal saline often required intravenous morphine, but still experienced a higher degree of pain and tolerated less external rotation.
Conclusions: An ambulatory CISB considerably decreases the time until readiness for discharge after shoulder arthroplasty, primarily by providing potent analgesia that permits greater passive shoulder movement and the avoidance of intravenous opioids. Additional research is required to define the appropriate subset of patients and assess the incidence of complications associated with earlier discharge.
Source: PubMed
Bevorstehende klinische Studien
-
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.Noch keine RekrutierungNicht-kleinzelligem LungenkrebsChina
-
RenJi HospitalChanghai Hospital; First People's Hospital of Hangzhou; West China Hospital; Chengdu... und andere MitarbeiterNoch keine Rekrutierung
-
RenJi HospitalChanghai Hospital; First People's Hospital of Hangzhou; West China Hospital; Chengdu... und andere MitarbeiterRekrutierung
-
CSPC Megalith Biopharmaceutical Co.,Ltd.Noch keine RekrutierungFortgeschrittene solide Tumoren
-
Foundation EndourologyThe International Alliance of UrolithiasisRekrutierung
-
Istanbul Galata UniversityThe Scientific and Technological Research Council of TurkeyNoch keine RekrutierungSystemischer Lupus erythematodes(SLE)Türkei (türkiye)
-
Postgraduate Institute of Dental Sciences RohtakRekrutierung
-
Prof Ibrahim JanahiNoch keine RekrutierungObesity-associated AsthmaKatar
-
Sohag UniversityNoch keine RekrutierungParkinson-Krankheit
-
Greater Atlanta Integrative PediatricsRekrutierungAutismus-Spektrum-Störung | Autismus | ASD | Autismus-Spektrum-Störung (ASD)Vereinigte Staaten
-
The General Hospital of Western Theater CommandNoch keine RekrutierungThrombocytopenic Purpura, Immune
-
Guangdong Hengrui Pharmaceutical Co., LtdNoch keine RekrutierungGeneralisierte Myasthenia gravisChina