Mucosal and Nasal Involvement and Their Correlation With Smell and Taste Functions in Lichen Planus Patients (LP-NOSE)
Correlation of Mucosal and Nasal Involvement With Smell and Taste Functions in Patients With Lichen Planus
This study investigates smell and taste function in patients diagnosed with lichen planus, a chronic inflammatory condition affecting the skin and mucous membranes.
Adults aged 18-65 with lichen planus participated in taste and smell tests. Oral and nasal examinations were performed to check for mucosal involvement, and nasal endoscopy was used to further evaluate nasal involvement.
A healthy control group of similar age also underwent taste and smell tests to compare results with the lichen planus patients.
The study aims to better understand how lichen planus affects smell and taste, which may help improve patient care. Participation is voluntary, and all information collected will be kept confidential.
Descripción general del estudio
Estado
Condiciones
Descripción detallada
Tipo de estudio
Inscripción (Actual)
Contactos y Ubicaciones
Ubicaciones de estudio
-
-
Istanbul
-
Istanbul, Istanbul, Turquía (Türkiye), 34098
- S.B.U. Istanbul Training and Research Hospital
-
-
Criterios de participación
Criterio de elegibilidad
Edades elegibles para estudiar
- Adulto
- Adulto Mayor
Acepta Voluntarios Saludables
Método de muestreo
Población de estudio
Descripción
Inclusion Criteria:
Age 18-65 years Clinically diagnosed with lichen planus (patient group) Healthy individuals without lichen planus (control group) Willing and able to provide informed consent
Exclusion Criteria:
Nasal septum deviation Nasal polyposis, congenital olfactory dysfunction, chronic rhinosinusitis, or allergic rhinitis History of head trauma History of nasal or paranasal surgery Psychiatric or neurological disorders (e.g., Parkinson's disease, Alzheimer's disease) Persistent loss of smell following COVID-19 infection Pregnancy or breastfeeding
Plan de estudios
¿Cómo está diseñado el estudio?
Detalles de diseño
Cohortes e Intervenciones
Grupo / Cohorte |
Intervención / Tratamiento |
|---|---|
|
Group 1- Lichen Planus Patients
Participants undergo taste and smell testing, oral and nasal examinations, and nasal endoscopy to assess mucosal involvement.
|
Group 1 - Lichen Planus Patients: Participants undergo taste and smell testing to assess sensory function, oral and nasal examinations to evaluate mucosal involvement, and nasal endoscopy for detailed nasal assessment. Group 2 - Healthy Controls: Participants undergo taste and smell testing to provide comparative data for the lichen planus group. |
|
Group 2 - Healthy Controls
Participants undergo taste and smell testing to provide comparative data with the lichen planus group.
|
Group 1 - Lichen Planus Patients: Participants undergo taste and smell testing to assess sensory function, oral and nasal examinations to evaluate mucosal involvement, and nasal endoscopy for detailed nasal assessment. Group 2 - Healthy Controls: Participants undergo taste and smell testing to provide comparative data for the lichen planus group. |
¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
|
Smell and Taste Function
Periodo de tiempo: Day 1
|
Participants underwent standardized smell (olfactory) and taste (gustatory) tests to assess sensory function. Tests were performed on both lichen planus patients and healthy controls to compare results and evaluate the impact of mucosal involvement on smell and taste function. Time Frame: Single visit assessment |
Day 1
|
|
Smell and taste function in patients with lichen planus
Periodo de tiempo: Day 1
|
Participants underwent standardized smell (olfactory) and taste (gustatory) tests to assess sensory function.
Tests were performed on both lichen planus patients and healthy controls to compare results and evaluate the impact of mucosal involvement on smell and taste function.
|
Day 1
|
Colaboradores e Investigadores
Patrocinador
Investigadores
- Investigador principal: Yasemin Bolat Eren, MD, S.B.U. Istanbul Eğitim ve Araştırma Hastanesi, Dermatology Department
Fechas de registro del estudio
Fechas importantes del estudio
Inicio del estudio (Actual)
Finalización primaria (Actual)
Finalización del estudio (Actual)
Fechas de registro del estudio
Enviado por primera vez
Primero enviado que cumplió con los criterios de control de calidad
Publicado por primera vez (Actual)
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
Última actualización enviada que cumplió con los criterios de control de calidad
Última verificación
Más información
Términos relacionados con este estudio
Palabras clave
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
- LP-Nasal-2026-01
- LP-NOSE (Otro identificador: ISTANBUL TRH)
Plan de datos de participantes individuales (IPD)
¿Planea compartir datos de participantes individuales (IPD)?
Descripción del plan IPD
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
Estudia un producto de dispositivo regulado por la FDA de EE. UU.
Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .