Why have mortality rates for severe malnutrition remained so high?

C Schofield, A Ashworth, C Schofield, A Ashworth

Abstract

A review of the literature that has appeared over the past five decades indicates that the median case fatality from severe malnutrition has remained unchanged over this period and is typically 20-30%, with the highest levels (50-60%) being among those with oedematous malnutrition. A likely cause of this continuing high mortality is faulty case-management. A survey of treatment centres worldwide (n = 79) showed that for acutely ill children, inappropriate diets that are high in protein, energy and sodium and low in micronutrients are commonplace. Practices that could have fatal consequences, such as prescribing diuretics for oedema, were found to be widespread. Evidence of outmoded and conflicting teaching manuals also emerged. Since low mortality levels from malnutrition can be achieved using appropriate treatment regimens, updated treatment guidelines, which are practical and prescriptive rather than descriptive, need to be implemented as part of a comprehensive training programme.

References

    1. Eur J Clin Nutr. 1993 Oct;47(10):750-4
    1. Cent Afr J Med. 1956 Dec;2(12):425-9
    1. Eur J Clin Nutr. 1988 Sep;42(9):787-96
    1. World Rev Nutr Diet. 1980;35:87-95
    1. Eur J Clin Nutr. 1989 Nov;43(11):763-8
    1. Am J Clin Nutr. 1969 Feb;22(2):139-46
    1. Arch Dis Child. 1961 Jun;36:305-15
    1. Trop Doct. 1987 Oct;17(4):179-81
    1. Trop Doct. 1989 Apr;19(2):82-5
    1. Lancet. 1995 Feb 18;345(8947):453
    1. J Indian Med Assoc. 1961 Jun 16;36:557-65
    1. J Trop Pediatr. 1987 Feb;33(1):24-8
    1. Br Med J. 1950 Mar 25;1(4655):701-3
    1. Lancet. 1963 May 4;1(7288):972-3
    1. Bull World Health Organ. 1993;71(6):713-22
    1. Ann Trop Paediatr. 1992;12(4):433-40
    1. Br Med J. 1960 Dec 17;2(5215):1759-66
    1. J Trop Pediatr. 1992 Oct;38(5):265-7
    1. Br J Nutr. 1976 Sep;36(2):255-63
    1. World Rev Nutr Diet. 1974;19:1-50
    1. Pediatr Infect Dis J. 1992 Dec;11(12):1030-6
    1. Clin Pediatr (Phila). 1968 Jul;7(7):425-31
    1. S Afr Med J. 1971 Dec 25;45(49):1427-49
    1. Trans R Soc Trop Med Hyg. 1994 Sep-Oct;88(5):594-5
    1. Am J Clin Nutr. 1959 Mar-Apr;7(2):161-5
    1. Trop Geogr Med. 1993;45(6):290-3
    1. J Trop Pediatr. 1983 Feb;29(1):61-4
    1. J Med Liban. 1964 Mar-Apr;17:85-96
    1. J Trop Pediatr. 1989 Jun;35(3):138-9
    1. Eur J Clin Nutr. 1993 Sep;47(9):658-65
    1. Lancet. 1969 Jul 12;2(7611):112
    1. J Trop Pediatr Environ Child Health. 1963 Sep;9:56-63
    1. West Indian Med J. 1962 Dec;11:217-27
    1. Harefuah. 1957 Apr 15;52(8):197
    1. J Trop Pediatr. 1980 Jun;26(3):123-6
    1. Trop Geogr Med. 1968 Sep;20(3):191-201
    1. J Trop Pediatr (1967). 1968 Sep;14(3):124-31
    1. Trans R Soc Trop Med Hyg. 1991 Sep-Oct;85(5):685-7
    1. Br J Nutr. 1967;21(1):155-65
    1. J Trop Pediatr Environ Child Health. 1975 Dec;21(6):329-33
    1. Lancet. 1994 Dec 24-31;344(8939-8940):1728-32

Source: PubMed

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