Self-related neural response to tailored smoking-cessation messages predicts quitting
Hannah Faye Chua, S Shaun Ho, Agnes J Jasinska, Thad A Polk, Robert C Welsh, Israel Liberzon, Victor J Strecher, Hannah Faye Chua, S Shaun Ho, Agnes J Jasinska, Thad A Polk, Robert C Welsh, Israel Liberzon, Victor J Strecher
Abstract
Tailored health interventions can be more effective in eliciting positive behavior change than generic interventions, but the underlying neural mechanisms are not yet understood. Here, 91 smokers participated in a functional magnetic resonance imaging session and a tailored smoking-cessation program. We found that increases in activation in self-related processing regions, particularly dorsomedial prefrontal cortex, to tailored messages predicted quitting during a 4-month follow-up.
Figures
Brain region activations during Tailored messages associated with quitting. Greater dmPFC activation predicted quitting and greater precuneus activation marginally predicting quitting. Regions are defined by areas preferentially engaged during Tailored messages in contrast to Untailored messages and also self-related processing in the Self-Appraisal task. The color map depicts the t-score and image coordinates are in MNI space.
References
- Lancaster T, Stead LF. Cochrane Database Syst Rev. 2005:CD001118.
- Brug J, Campbell M, van Assema P. Patient Educ Couns. 1999;36:145–156.
- Dijkstra A. Health Educ Res. 2005;20:527–539.
- Strecher V. Annu Rev Clin Psychol. 2007;3:53–76.
- Symons CS, Johnson BT. Psychol Bull. 1997;121:371–394.
- Northoff G, Bermpohl F. Trends Cogn Sci. 2004;8:1364–6613.
- Northoff G, et al. Neuroimage. 2006;31:440–457.
- Chua HF, Liberzon I, Welsh RC, Strecher VJ. Biol Psychiatry. 2009;65:165–168.
- Strecher VJ, et al. Am J Prev Med. 2008;34:373–381.
- Velicer WF, Prochaska JO. Addict Behav. 2004;29:51–60.
- Schmitz TW, Johnson SC. Neuroimage. 2006;30:1050–1058.
- van der Meer L, Costafreda S, Aleman A, David AS. Neurosci Biobehav Rev. 2010;34:935–946.
Source: PubMed