Vitamin E as an Antioxidant in Female Reproductive Health

Siti Syairah Mohd Mutalip, Sharaniza Ab-Rahim, Mohd Hamim Rajikin, Siti Syairah Mohd Mutalip, Sharaniza Ab-Rahim, Mohd Hamim Rajikin

Abstract

Vitamin E was first discovered in 1922 as a substance necessary for reproduction. Following this discovery, vitamin E was extensively studied, and it has become widely known as a powerful lipid-soluble antioxidant. There has been increasing interest in the role of vitamin E as an antioxidant, as it has been discovered to lower body cholesterol levels and act as an anticancer agent. Numerous studies have reported that vitamin E exhibits anti-proliferative, anti-survival, pro-apoptotic, and anti-angiogenic effects in cancer, as well as anti-inflammatory activities. There are various reports on the benefits of vitamin E on health in general. However, despite it being initially discovered as a vitamin necessary for reproduction, to date, studies relating to its effects in this area are lacking. Hence, this paper was written with the intention of providing a review of the known roles of vitamin E as an antioxidant in female reproductive health.

Keywords: antioxidant; reproduction; tocopherol; tocotrienol; vitamin E.

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Structure differences between tocopherols (TOCs) and tocotrienols (TCTs). TOCs have saturated side chains, while TCTs have unsaturated side chains. The latter are shown by the presence of three double bonds in TCTs (circled) [14].

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Source: PubMed

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