Epidural anesthesia for pilonidal sinus surgery: ropivacaine versus levobupivacaine

Zeynep Nur Orhon, Emine Nursen Koltka, Sibel Devrim, Sevil Tüfekçi, Serkan Doğru, Melek Çelik, Zeynep Nur Orhon, Emine Nursen Koltka, Sibel Devrim, Sevil Tüfekçi, Serkan Doğru, Melek Çelik

Abstract

Background: Epidural anesthesia is one of the best options for lower abdominal and lower limb surgery. However, there have been insufficient reports regarding the use of epidural anesthesia for pilonidal sinus surgery. The present study was performed to compare the clinical profiles of epidural block performed with 0.75% levobupivacaine and 0.75% ropivacaine in this procedure.

Methods: Thirty patients undergoing pilonidal sinus surgery were randomly allocated into two groups: one group received levobupivacaine and the other received ropivacaine at 0.75% in a volume of 10 ml. Arterial blood pressure, heart rate, oxygen saturation, the onset time of analgesia and duration of block, highest sensory block level, perioperative and postoperative side effects, and patients' and surgeons' satisfaction were recorded.

Results: Hemodynamic stability was maintained in both groups throughout surgery. The onset time of analgesia (the time from epidural injection of local anesthetic to reach L2 sensorial block) was 6.26 ± 3.49 min in the levobupivacaine group and 4.06 ± 1.75 min in the ropivacaine group (P = 0.116). The duration of sensorial block (time for regression of sensory block to L2) was 297.73 ± 70.94 min in group L and 332.40 ± 102.22 min in group R (P = 0.110). Motor block was not seen in any of the patients in the study groups. Patients' and surgeons' satisfaction with the anesthetic technique were mostly excellent in both groups.

Conclusions: In patients undergoing pilonidal sinus surgery, both levobupivacaine and ropivacaine produce rapid and excellent epidural block without leading to motor block or significant side effects. Although not statistically significant, the onset time of anesthesia was shorter and the duration of effect was longer with ropivacaine than with levobupivacaine in this study.

Keywords: Epidural anesthesia; Levobupivacaine; Pilonidal sinus surgery; Ropivacaine.

Figures

Fig. 1. Mean arterial pressure (MAP) changes…
Fig. 1. Mean arterial pressure (MAP) changes during surgery in the two groups. R: Ropivacaine, L: Levobupivacaine.
Fig. 2. Heart rate measurements during surgery…
Fig. 2. Heart rate measurements during surgery in the two groups. R: Ropivacaine, L: Levobupivacaine.

References

    1. Smith LE. Ambulatory surgery for anorectal diseases: an update. South Med J. 1986;79:163–166.
    1. Hunt L, Luck AJ, Rudkin G, Hewett PJ. Day-case haemorrhoidectomy. Br J Surg. 1999;86:255–258.
    1. Thompson-Fawcett MW, Cook TA, Baigrie RJ, Mortensen NJ. What patients think of day-surgery proctology. Br J Surg. 1998;85:1388.
    1. Fleischer M, Marini CP, Statman R, Capella J, Shevde K. Local anesthesia is superior to spinal anesthesia for anorectal surgical procedures. Am Surg. 1994;60:812–815.
    1. Li S, Coloma M, White PF, Watcha MF, Chiu JW, Li H, et al. Comparison of the costs and recovery profiles of three anesthetic techniques for ambulatory anorectal surgery. Anesthesiology. 2000;93:1225–1230.
    1. Neal JM, Bernards CM, Butterworth JF, 4th, Di Gregorio G, Drasner K, Hejtmanek MR, et al. ASRA practice advisory on local anesthetic systemic toxicity. Reg Anesth Pain Med. 2010;35:152–161.
    1. Cox B, Durieux ME, Marcus MA. Toxicity of local anaesthetics. Best Pract Res Clin Anaesthesiol. 2003;17:111–136.
    1. Bund M, Heine J, Jaeger K. Complications due to patient positioning: anaesthesiological considerations. Anasthesiol Intensivmed Notfallmed Schmerzther. 2005;40:329–339.
    1. Gan TJ, Meyer T, Apfel CC, Chung F, Davis PJ, Eubanks S, et al. Consensus guidelines for managing postoperative nausea and vomiting. Anesth Analg. 2003;97:62–71.
    1. Smith HS, Smith EJ, Smith BR. Postoperative nausea and vomiting. Ann Palliat Med. 2012;1:94–102.
    1. Tarkkila P. Complications of Regional Anesthesia. 2nd ed. New York: Springer Science+Business Media, LLC; 2007. pp. 149–166.
    1. Twomey C, Tsui BC. Complications of Regional Anesthesia. 2nd ed. New York: Springer Science+Business Media, LLC; 2007. pp. 167–192.
    1. Casati A, Putzu M. Bupivacaine, levobupivacaine and ropivacaine: are they clinically different? Best Pract Res Clin Anaesthesiol. 2005;19:247–268.
    1. Kuthiala G, Chaudhary G. Ropivacaine: A review of its pharmacology and clinical use. Indian J Anaesth. 2011;55:104–110.
    1. Bajwa SJ, Kaur J. Clinical profile of levobupivacaine in regional anesthesia: A systematic review. J Anaesthesiol Clin Pharmacol. 2013;29:530–539.
    1. Bromage PR. A comparison of the hydrochloride and carbon dioxide salts of lidocaine and prilocaine in epidural analgesia. Acta Anaesthesiol Scand Suppl. 1965;16:55–69.
    1. Pala Y, Okur S, Taşpınar V, Örnek D, Dönmez F, Barçın S, et al. Pilonidal sinus cerrahisinde selektif segmental epidural anestezi uygulaması. Türk Anest Rean Der Dergisi. 2010;38:190–200.
    1. Peduto VA, Baroncini S, Montanini S, Proietti R, Rosignoli L, Tufano R, et al. A prospective, randomized, double-blind comparison of epidural levobupivacaine 0.5% with epidural ropivacaine 0.75% for lower limb procedures. Eur J Anaesthesiol. 2003;20:979–983.
    1. Casati A, Santorsola R, Aldegheri G, Ravasi F, Fanelli G, Berti M, et al. Intraoperative epidural anesthesia and postoperative analgesia with levobupivacaine for major orthopedic surgery: a double-blind, randomized comparison of racemic bupivacaine and ropivacaine. J Clin Anesth. 2003;15:126–131.
    1. Koch T, Fichtner A, Schwemmer U, Standl T, Volk T, Engelhard K, et al. Levobupivacaine for epidural anaesthesia and postoperative analgesia in hip surgery: a multi-center efficacy and safety equivalence study with bupivacaine and ropivacaine. Anaesthesist. 2008;57:475–482.
    1. McGlade DP, Kalpokas MV, Mooney PH, Buckland MR, Vallipuram SK, Hendrata MV, et al. Comparison of 0.5% ropivacaine and 0.5% bupivacaine in lumbar epidural anaesthesia for lower limb orthopaedic surgery. Anaesth Intensive Care. 1997;25:262–266.
    1. Yang CW, Jung SM, Kwon HU, Kang PS, Ryu SH. Comparison of Epidural Anesthesia with 0.5% Levobupivacaine and 0.5% Ropivacaine for Cesarean Section. Korean J Anesthesiol. 2007;52:284–290.
    1. Taspinar V, Sahin A, Dönmez NF, Pala Y, Selçuk A, Ozcan M, et al. Low dose ropivacaine or levobupivacaine walking spinal anesthesia in ambulatory inguinal herniorrhaphy. J Anesth. 2011;25:219–224.

Source: PubMed

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