Acute encephalitis caused by intrafamilial transmission of enterovirus 71 in adult

Tsuyoshi Hamaguchi, Hironori Fujisawa, Kenji Sakai, Soichi Okino, Naoko Kurosaki, Yorihiro Nishimura, Hiroyuki Shimizu, Masahito Yamada, Tsuyoshi Hamaguchi, Hironori Fujisawa, Kenji Sakai, Soichi Okino, Naoko Kurosaki, Yorihiro Nishimura, Hiroyuki Shimizu, Masahito Yamada

Abstract

Enterovirus 71 (EV71) is a common cause of hand, foot, and mouth disease and sometimes causes severe neurologic complications, mainly in children. We report a case of adult-onset encephalitis caused by intrafamilial transmission of a subgenogroup C4 strain of EV71. This case elucidates the risk for EV71 encephalitis even in adults.

Figures

Figure 1
Figure 1
Magnetic resonance images of the brain. A) Hyperintense lesions in the tegmentum of the pons in the axial section of the fluid-attenuated inversion recovery image. B) In the sagittal section of the T2-weighted image, hyperintense lesions are present in the tegmentum of the midbrain, pons, and medulla oblongata.
Figure 2
Figure 2
Phylogenetic analysis of EV71 based on the entire VP1 sequences. The tree was prepared by the neighbor-joining method by using the EV71 strains in the world as described previously (6) and newly identified subgenogroup C4 strains (7,8) were also included in the analysis.

References

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Source: PubMed

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