Knee complaints vary with age and gender in the adult population. Population-based reference data for the Knee injury and Osteoarthritis Outcome Score (KOOS)

Przemyslaw T Paradowski, Stefan Bergman, Anne Sundén-Lundius, L Stefan Lohmander, Ewa M Roos, Przemyslaw T Paradowski, Stefan Bergman, Anne Sundén-Lundius, L Stefan Lohmander, Ewa M Roos

Abstract

Background: Self-reported knee complaints may vary with age and gender. Reference data from the adult population would help to better interpret the outcome of interventions due to knee complaints. The objectives of the present study were to describe the variation of self-reported knee pain, function and quality of life with age and gender in the adult population and to establish population-based reference data for the Knee injury and Osteoarthritis Outcome Score (KOOS).

Methods: Population-based cohort retrieved from the national population register. The knee-specific Knee injury and Osteoarthritis Outcome Score (KOOS) was mailed to 840 subjects aged 18-84 yrs.

Results: 68% response rate. Women in the age group 55-74 reported more knee-related complaints in all the KOOS subscales than age-matched men. The differences were significant for the subscales Pain (p = 0.027), Symptoms (p = 0.003) and ADL function (p = 0.046). In men, worse ADL and Sport and Recreation function was seen in the oldest age group 75-84 years compared to the younger age groups (p < 0.030). In women, worse Pain (p < 0.007), ADL (p < 0.030), Sport and Recreation (p < 0.001) and QOL (p < 0.002) were seen already in the age group 55-74 compared to the younger age groups.

Conclusion: We found pain and other symptoms, physical function, and knee-related quality of life to vary with age and gender implying the use of age- and gender matched reference values for improved understanding of the outcome after interventions due to knee injury and knee OA.

Figures

Figure 1
Figure 1
Flow chart that details the study procedure and formation of the patient cohort.
Figure 2
Figure 2
Mean KOOS scores of the subscales pain, symptoms, activities of daily living, sports/recreation, and quality of life for men and women in different age groups.

References

    1. Altman R, Brandt K, Hochberg M, Moskowitz R, Bellamy N, Bloch DA, Buckwalter J, Dougados M, Ehrlich G, Lequesne M, Lohmander S, Murphy WA, Jr, Rosario-Jansen T, Schwartz B, Trippel S. Design and conduct of clinical trials in patients with osteoarthritis: recommendations from a task force of the Osteoarthritis Research Society. Results from a workshop. Osteoarthritis Cartilage. 1996;4:217–43. doi: 10.1016/S1063-4584(05)80101-3.
    1. Bellamy N, Kirwan J, Boers M, Brooks P, Strand V, Tugwell P, Altman R, Brandt K, Dougados M, Lequesne M. Recommendations for a core set of outcome measures for future phase III clinical trials in knee, hip, and hand osteoarthritis. Consensus development at OMERACT III. J Rheumatol. 1997;24:799–802.
    1. Roos EM, Roos HP, Lohmander LS, Ekdahl C, Beynnon BD. Knee Injury and Osteoarthritis Outcome Score (KOOS)–development of a self-administered outcome measure. J Orthop Sports Phys Ther. 1998;28:88–96.
    1. Roos EM, Roos HP, Ekdahl C, Lohmander LS. Knee injury and Osteoarthritis Outcome Score (KOOS)–validation of a Swedish version. Scand J Med Sci Sports. 1998;8:439–48.
    1. Roos EM, Toksvig-Larsen S. Knee injury and Osteoarthritis Outcome Score (KOOS) – validation and comparison to the WOMAC in total knee replacement. Health Qual Life Outcomes. 2003;1:17. doi: 10.1186/1477-7525-1-17.
    1. Demirdjian AM, Petrie SG, Guanche CA, Thomas KA. The outcomes of two knee scoring questionnaires in a normal population. Am J Sports Med. 1998;26:46–51.
    1. Jinks C, Jordan K, Croft P. Measuring the population impact of knee pain and disability with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain. 2002;100:55–64. doi: 10.1016/S0304-3959(02)00239-7.
    1. Bremner-Smith AT, Ewings P, Weale AE. Knee scores in a 'normal' elderly population. Knee. 2004;11:279–82. doi: 10.1016/j.knee.2003.06.001.
    1. Jinks C, Jordan K, Ong BN, Croft P. A brief screening tool for knee pain in primary care (KNEST). 2. Results from a survey in the general population aged 50 and over. Rheumatology (Oxford) 2004;43:55–61. doi: 10.1093/rheumatology/keg438.
    1. Bellamy N, Buchanan W, Goldsmith CH. Validation study of WOMAC: A health status instrument for measuring clinically important patient-relevant outcomes following total hip or knee arthroplasty in osteoarthritis. Orthop Rheumatol. 1988;1:95–108.
    1. Garratt AM, Brealey S, Gillespie WJ. Patient-assessed health instruments for the knee: a structured review. Rheumatology (Oxford) 2004;43:1414–23. doi: 10.1093/rheumatology/keh362.
    1. Picavet HS, Schouten JS. Musculoskeletal pain in the Netherlands: prevalences, consequences and risk groups, the DMC(3)-study. Pain. 2003;102:167–78. doi: 10.1016/s0304-3959(02)00372-x.
    1. Brinker MR, Lund PJ, Barrack RL. Demographic biases of scoring instruments for the results of total knee arthroplasty. J Bone Joint Surg Am. 1997;79:858–65.
    1. Ritter MA, Thong AE, Davis KE, Berend ME, Meding JB, Faris PM. Long-term deterioration of joint evaluation scores. J Bone Joint Surg Br. 2004;86:438–42. doi: 10.1302/0301-620X.86B3.14243.
    1. Roos EM, Roos HP, Ryd L, Lohmander LS. Substantial disability 3 months after arthroscopic partial meniscectomy: A prospective study of patient-relevant outcomes. Arthroscopy. 2000;16:619–26.
    1. W-Dahl A, Toksvig-Larsen S, Roos EM. A 2-year prospective study of patient-relevant outcomes in patients operated on for knee osteoarthritis with tibial osteotomy. BMC Musculoskelet Disord. 2005;6:18. doi: 10.1186/1471-2474-6-18.
    1. von Porat A, Roos EM, Roos H. High prevalence of osteoarthritis 14 years after an anterior cruciate ligament tear in male soccer players – A study of radiographic and patient-relevant outcomes. Ann Rheum Dis. 2004;63:269–73. doi: 10.1136/ard.2003.008136.
    1. Roos EM, Roos HP, Lohmander LS. WOMAC Osteoarthritis Index–additional dimensions for use in subjects with post-traumatic osteoarthritis of the knee. Western Ontario and MacMaster Universities. Osteoarthritis Cartilage. 1999;7:216–21. doi: 10.1053/joca.1998.0153.
    1. Verbrugge LM. Women, men, and osteoarthritis. Arthritis Care Res. 1995;8:212–20.
    1. Felson DT, Nevitt MC. Estrogen and osteoarthritis: how do we explain conflicting study results? Prev Med. 1999;28:445–8. doi: 10.1006/pmed.1999.0491.
    1. Fillingim RB. Sex, gender, and pain: women and men really are different. Curr Rev Pain. 2000;4:24–30.
    1. McKinlay SM, Bifano NL, McKinlay JB. Smoking and age at menopause in women. Ann Intern Med. 1985;103:350–356.
    1. Thomas E, Peat G, Harris L, Wilkie R, Croft PR. The prevalence of pain and pain interference in a general population of older adults: cross-sectional findings from the North Staffordshire Osteoarthritis Project (NorStOP) Pain. 2004;110:361–8. doi: 10.1016/j.pain.2004.04.017.
    1. Bergman S, Herrstrom P, Hogstrom K, Petersson IF, Svensson B, Jacobsson LT. Chronic musculoskeletal pain, prevalence rates, and sociodemographic associations in a Swedish population study. J Rheumatol. 2001;28:1369–77.
    1. Robertsson O, Dunbar M, Pehrsson T, Knutson K, Lidgren L. Patient satisfaction after knee arthroplasty: a report on 27,372 knees operated on between 1981 and 1995 in Sweden. Acta Orthop Scand. 2000;71:262–7. doi: 10.1080/000164700317411852.
    1. Croft P, Lewis M, Wynn Jones C, Coggon D, Cooper C. Health status in patients awaiting hip replacement for osteoarthritis. Rheumatology (Oxford) 2002;41:1001–7. doi: 10.1093/rheumatology/41.9.1001.
    1. Baker P, Reading I, Cooper C, Coggon D. Knee disorders in the general population and their relation to occupation. Occup Environ Med. 2003;60:794–7. doi: 10.1136/oem.60.10.794.
    1. Sullivan M, Karlsson J. SF-36 Hälsoenkät: Swedish Manual and Interpretation Guide. Gothenburg, Sweden: Health Care Unit, Sahlgrenska Hospital; 1994.

Source: PubMed

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