A smartphone application to improve adherence to vitamin and mineral supplementation after bariatric surgery

Kristina Spetz, Mari Hult, Torsten Olbers, Stephanie Bonn, Sanna Svedjeholm, Ylva Trolle Lagerros, Ellen Andersson, Kristina Spetz, Mari Hult, Torsten Olbers, Stephanie Bonn, Sanna Svedjeholm, Ylva Trolle Lagerros, Ellen Andersson

Abstract

Objective: This trial evaluated a smartphone application's effectiveness in improving adherence to vitamin and mineral supplementation postoperatively.

Methods: This study was a randomized controlled trial comprising 140 patients undergoing bariatric surgery (gastric bypass or sleeve gastrectomy). Participants were randomized 1:1 to the 12-week intervention, using the smartphone application PromMera, or to standard care. The primary end point was adherence to vitamin and mineral supplementation.

Results: Initiation rate and overall adherence to supplementation were high in both groups. Change in objectively measured adherence rate from before the intervention to 1 year post surgery, measured with pharmacy refill data, did not differ between groups for vitamin B12 (-9.6% [SD = 27%] vs. -9.3% [SD = 30%]; p = 0.48) or calcium/vitamin D (-12.3% [SD = 29%] vs. -11.5% [SD = 32%]; p = 0.44). A modest effect on the secondary end point (subjectively measured adherence, using the Medication Adherence Report Scale-5) was seen immediately after the intervention (intervention group 0.00 [SD = 1.3] vs. control group -1.2 [SD = 3.5]; p = 0.021), but this effect did not persist 1 year post surgery. No differences were detected in the prevalence of biochemical deficiencies.

Conclusions: The use of the smartphone application PromMera did not obtain a lasting improvement in adherence to vitamin and mineral supplementation 1 year post bariatric surgery.

Trial registration: ClinicalTrials.gov NCT03480464.

Conflict of interest statement

Torsten Olbers has received reimbursement unrelated to the submitted article from the following: Johnson & Johnson (advisory board, educational activities) and NovoNordisk A/S (advisory board, educational activities), with all reimbursement directed to his institution. The other authors declared no conflict of interest.

© 2022 The Authors. Obesity published by Wiley Periodicals LLC on behalf of The Obesity Society (TOS).

Figures

FIGURE 1
FIGURE 1
PromMera study flowchart
FIGURE 2
FIGURE 2
The PromMera smartphone application [Color figure can be viewed at wileyonlinelibrary.com]
FIGURE 3
FIGURE 3
Use of the PromMera application during the intervention

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Source: PubMed

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