Comparison of PCR and culture for screening of vancomycin-resistant Enterococci: highly disparate results for vanA and vanB
Anton Mak, Mark A Miller, George Chong, Yury Monczak, Anton Mak, Mark A Miller, George Chong, Yury Monczak
Abstract
We compared PCR to conventional culture for the detection of vancomycin-resistant enterococci (VRE) in 30,835 rectal samples over a 3-year period. The positive and negative predictive values of vanB PCR were 1.42% and 99.9%, respectively. A positive vanB result by PCR is poorly predictive and necessitates culture for differentiation of VRE-positive and -negative individuals.
Source: PubMed