Possible outbreak of streptomycin-resistant Mycobacterium tuberculosis Beijing in Benin

Dissou Affolabi, Frank Faïhun, N'Dira Sanoussi, Gladys Anyo, Isdore Chola Shamputa, Leen Rigouts, Luc Kestens, Séverin Anagonou, Françoise Portaels, Dissou Affolabi, Frank Faïhun, N'Dira Sanoussi, Gladys Anyo, Isdore Chola Shamputa, Leen Rigouts, Luc Kestens, Séverin Anagonou, Françoise Portaels

Abstract

Using geographic information system and molecular tools, we characterized a possible outbreak of tuberculosis caused by Mycobacterium tuberculosis Beijing strain in 17 patients in Cotonou, Benin, during July 2005-October 2006. Most patients lived or worked in the same area and frequented the same local drinking bar. The isolates were streptomycin resistant.

Figures

Figure
Figure
Maps showing residences and workplaces of Mycobacterium tuberculosis patients in Xwlacodji, Cotonou, Benin, 2005–2006.

References

    1. Affolabi D, Anyo G, Faïhun F, Sanoussi N, Shamputa IC, Rigouts L, et al. First molecular epidemiological study of tuberculosis in Benin. Int J Tuberc Lung Dis. 2009;13:317–22.
    1. Niobe-Eyangoh SN, Kuaban C, Sorlin P, Cunin P, Thonnon J, Sola C, et al. Genetic biodiversity of Mycobacterium tuberculosis complex strains from patients with pulmonary tuberculosis in Cameroon. J Clin Microbiol. 2003;41:2547–53. 10.1128/JCM.41.6.2547-2553.2003
    1. Cadmus S, Palmer S, Okker M, Dale J, Gover K, Smith N, et al. Molecular analysis of human and bovine tubercle bacilli from a local setting in Nigeria. J Clin Microbiol. 2006;44:29–34. 10.1128/JCM.44.1.29-34.2006
    1. Godreuil S, Torrea G, Terru D, Chevenet F, Diagbouga S, Supply P, et al. First molecular epidemiology study of Mycobacterium tuberculosis in Burkina Faso. J Clin Microbiol. 2007;45:921–7. 10.1128/JCM.01918-06
    1. Supply P, Allix C, Lesjean S, Cardoso-Oelemann M, Rüsch-Gerdes S, Willery E, et al. Proposal for standardization of optimized mycobacterial interspersed repetitive unit-variable-number tandem repeat typing of Mycobacterium tuberculosis. J Clin Microbiol. 2006;44:4498–510. 10.1128/JCM.01392-06
    1. Goloubeva V, Lecocq M, Lassowsky P, Matthys F, Portaels F, Bastian I. Evaluation of mycobacteria growth indicator tube for direct and indirect drug susceptibility testing of Mycobacterium tuberculosis from respiratory specimens in a Siberian prison hospital. J Clin Microbiol. 2001;39:1501–5. 10.1128/JCM.39.4.1501-1505.2001
    1. Canetti G, Fox W, Khomenko A, Malher HT, Menon NK, Mitchison DA, et al. Advances in techniques of testing mycobacterial drug sensitivity and the use of sensitivity tests in tuberculosis control programmes. Bull World Health Organ. 1969;41:21–43.
    1. Rieder HL, Van Deun A, Kam KM, Kim SJ, Chonde TM. Trébucq et al. Priorities for tuberculosis bacteriology services in low-income countries, 2nd ed. Paris: International Union Against Tuberculosis and Lung Disease; 2007.
    1. European Concerted Action on New Generation Genetic Markers and Techniques for the Epidemiology and Control of Tuberculosis. Beijing/W genotype Mycobacterium tuberculosis and drug resistance. Emerg Infect Dis. 2006;12:736–41.
    1. Hanekom M, van der Spuy GD, Gey van Pittius NC, McEvoy CR, Ndabambi SL, Victor TC, et al. Evidence that the spread of Mycobacterium tuberculosis strains with the Beijing genotype is human population dependent. J Clin Microbiol. 2007;45:2263–6. 10.1128/JCM.02354-06
    1. Shamputa IC, Jugheli L, Sadradze N, Willery E, Portaels F, Supply P, et al. Mixed infection and clonal representativeness of a single sputum sample in tuberculosis patients from a penitentiary hospital in Georgia. Respir Res. 2006;7:99. 10.1186/1465-9921-7-99
    1. Cronin W, Rodriguez E, Valway S, Bur S, Hooper N, Smithwick R, et al. Pseudo-outbreak of tuberculosis in an acute-care general hospital: epidemiology and clinical implications. Infect Control Hosp Epidemiol. 1998;19:345–7.
    1. Bearman G, Vaamonde C, Larone D, Drusin L, Zuccotti G. Pseudo-outbreak of multidrug-resistant Mycobacterium tuberculosis associated with presumed laboratory processing contamination. Infect Control Hosp Epidemiol. 2002;23:620–2. 10.1086/501982
    1. Tanser FC, Le Sueur D. The application of geographical information systems to important public health problems in Africa. Int J Health Geogr. 2002;1:4. 10.1186/1476-072X-1-4

Source: PubMed

3
Iratkozz fel