Cost-effectiveness analysis of a multifactorial fall prevention intervention in older home care clients at risk for falling

Wanrudee Isaranuwatchai, Johnna Perdrizet, Maureen Markle-Reid, Jeffrey S Hoch, Wanrudee Isaranuwatchai, Johnna Perdrizet, Maureen Markle-Reid, Jeffrey S Hoch

Abstract

Background: Falls among older adults can cause serious morbidity and pose economic burdens on society. Older age is a known risk factor for falls and age has been shown to influence the effectiveness of fall prevention programs. To our knowledge, no studies have explicitly investigated whether cost-effectiveness of a multifactorial fall prevention intervention (the intervention) is influenced by age. This economic evaluation explores: 1) the cost-effectiveness of a multifactorial fall prevention intervention compared to usual care for community-dwelling adults ≥ 75 years at risk of falling in Canada; and 2) the influence of age on the cost-effectiveness of the intervention.

Methods: Net benefit regression was used to examine the cost-effectiveness of the intervention with willingness-to-pay values ranging from $0-$50,000. Effects were measured as change in the number of falls, from baseline to 6-month follow-up. Costs were measured using a societal perspective. The cost-effectiveness analysis was conducted for both the total sample and by age subgroups (75-84 and 85+ years).

Results: For the total sample, the intervention was not economically attractive. However, the intervention was cost-effective at higher willingness-to-pay (WTP) (≥ $25,000) for adults 75-84 years and at lower WTP (< $5,000) for adults 85+ years.

Conclusions: The cost-effectiveness of the intervention depends on age and decision makers' WTP to prevent falls. Understanding the influence of age on the cost-effectiveness of an intervention may help to target resources to those who benefit most.

Trial registration: Retrospectively registered. Clinicaltrials.gov identifier: NCT00463658 (18 April 2007).

Keywords: Age; Cost-effectiveness analysis; Fall prevention; Multifactorial intervention; Older adults.

Conflict of interest statement

Ethics approval and consent to participate

This study was conducted in accordance with the Tri-Council Policy Statement, “Ethical Conduct for Research Involving Humans” [45]. Ethics approval for the study was obtained from the McMaster University Research and Ethics Board and renewed yearly as required (# 05–279). All participants provided written informed consent for participation.

Consent for publication

N/A

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
A cost-effectiveness acceptability curve indicates the probability that the intervention is cost-effective compared to usual care for a given willingness-to-pay value. The y-axis represents the probability that the intervention was cost-effective, and the x-axis represents a range of willingness-to-pay values. Cost-effectiveness acceptability curves for all (75+ years), young-old (75-84 years), and old-old (85-95 years)

References

    1. Gillespie LD, Robertson MC, Gillespie WJ, Sherrington C, Gates S, Clemson LM, et al. Interventions for preventing falls in older people living in the community. The Cochrane database of systematic reviews. 2012;9:CD007146.
    1. Gielen AC, McDonald EM, Shields W. Unintentional home injuries across the life span: problems and solutions. Annu Rev Public Health. 2015;36:231–253. doi: 10.1146/annurev-publhealth-031914-122722.
    1. Farag I, Howard K, Ferreira ML, Sherrington C. Economic modelling of a public health programme for fall prevention. Age Ageing. 2015;44(3):409–414. doi: 10.1093/ageing/afu195.
    1. Rubenstein LZ. Falls in older people: epidemiology, risk factors and strategies for prevention. Age and ageing. 2006;35(Suppl 2):ii37–ii41.
    1. Fletcher P, Berg K, Dalby D, Hirdes J. Risk factors for falling among community-based seniors. Journal of Patient Safety. 2009;5(2):61–66. doi: 10.1097/PTS.0b013e3181a551ed.
    1. Scuffham P, Chaplin S, Legood R. Incidence and costs of unintentional falls in older people in the United Kingdom. J Epidemiol Community Health. 2003;57(9):740–744. doi: 10.1136/jech.57.9.740.
    1. Heinrich S, Rapp K, Rissmann U, Becker C, Konig HH. Cost of falls in old age: a systematic review. Osteoporos Int. 2010;21(6):891–902. doi: 10.1007/s00198-009-1100-1.
    1. Summary of the Updated American Geriatrics Society/British Geriatrics Society Clinical Practice Guideline for Prevention of Falls in Older Persons. Journal of the American Geriatrics Society. 2011;59(1):148–57.
    1. Markle-Reid M, Browne G, Gafni A, Roberts J, Weir R, Thabane L, et al. A cross-sectional study of the prevalence, correlates, and costs of falls in older home care clients' at risk'for falling. Canadian Journal on Aging. 2010;29(1):119. doi: 10.1017/S0714980809990365.
    1. Karlsson MK, Magnusson H, von Schewelov T, Rosengren BE. Prevention of falls in the elderly--a review. Osteoporos Int. 2013;24(3):747–762. doi: 10.1007/s00198-012-2256-7.
    1. Pfortmueller CA, Lindner G, Exadaktylos AK. Reducing fall risk in the elderly: risk factors and fall prevention, a systematic review. Minerva Med. 2014;105(4):275–281.
    1. Svantesson U, Babagbemi B, Foster L, Alricsson M. Influences on modern multifactorial falls prevention interventions and fear of falling in non-frail older adults: a literature review. Journal of Clinical Medicine Research. 2014;6(5):314–320.
    1. Campbell AJ, Robertson MC. Rethinking individual and community fall prevention strategies: a meta-regression comparing single and multifactorial interventions. Age Ageing. 2007;36(6):656–662. doi: 10.1093/ageing/afm122.
    1. Beard J, Rowell D, Scott D, van Beurden E, Barnett L, Hughes K, et al. Economic analysis of a community-based falls prevention program. Public Health. 2006;120(8):742–751. doi: 10.1016/j.puhe.2006.04.011.
    1. Rizzo JA, Baker DI, McAvay G, Tinetti ME. The cost-effectiveness of a multifactorial targeted prevention program for falls among community elderly persons. Med Care. 1996;34(9):954–969. doi: 10.1097/00005650-199609000-00007.
    1. Carande-Kulis V, Stevens JA, Florence CS, Beattie BL, Arias I. A cost-benefit analysis of three older adult fall prevention interventions. J Saf Res. 2015;52:65–70. doi: 10.1016/j.jsr.2014.12.007.
    1. Wu S, Keeler EB, Rubenstein LZ, Maglione MA, Shekelle PG. A cost-effectiveness analysis of a proposed national falls prevention program. Clin Geriatr Med. 2010;26(4):751–766. doi: 10.1016/j.cger.2010.07.005.
    1. Patil R, Kolu P, Raitanen J, Valvanne J, Kannus P, Karinkanta S, et al. Cost-effectiveness of vitamin D supplementation and exercise in preventing injurious falls among older home-dwelling women: findings from an RCT. Osteoporos Int. 2016;27(1):193–201. doi: 10.1007/s00198-015-3240-9.
    1. Poole CD, Smith J, Davies JS. Cost-effectiveness and budget impact of empirical vitamin D therapy on unintentional falls in older adults in the UK. BMJ Open. 2015;5(9) doi: 10.1136/bmjopen-2015-007910.
    1. Hendriks M, Evers S, Bleijlevens M, van Haastregt J, Crebolder H, van Eijk J. Cost-effectiveness of a multidisciplinary fall prevention program in community-dwelling elderly people: a randomized controlled trial. Int J Technol Assess Health Care. 2008;24(2):193–202. doi: 10.1017/S0266462308080276.
    1. Davis J, Robertson MC, Ashe M, Liu-Ambrose T, Khan K, Marra C. Does a home-based strength and balance programme in people aged > or =80 years provide the best value for money to prevent falls? A systematic review of economic evaluations of falls prevention intervention. Br J Sports Med. 2010;44(2):80–89. doi: 10.1136/bjsm.2008.060988.
    1. Jenkyn KB, Hoch JS, Speechley M. How much are we willing to pay to prevent a fall? Cost-effectiveness of a multifactorial falls prevention program for community-dwelling older adults. Canadian Journal on Aging. 2012;31(2):121–137. doi: 10.1017/S0714980812000074.
    1. Frick KD, Kung JY, Parrish JM, Narrett MJ. Evaluating the cost-effectiveness of fall prevention programs that reduce fall-related hip fractures in older adults. J Am Geriatr Soc. 2010;58(1):136–141. doi: 10.1111/j.1532-5415.2009.02575.x.
    1. Church J, Goodall S, Norman R, Haas M. The cost-effectiveness of falls prevention interventions for older community-dwelling Australians. Aust N Z J Public Health. 2012;36(3):241–248. doi: 10.1111/j.1753-6405.2011.00811.x.
    1. Peeters GM, Heymans MW, de Vries OJ, Bouter LM, Lips P, van Tulder MW. Multifactorial evaluation and treatment of persons with a high risk of recurrent falling was not cost-effective. Osteoporos Int. 2011;22(7):2187–2196. doi: 10.1007/s00198-010-1438-4.
    1. Irvine L, Conroy S, Sach T, Gladman J, Harwood R, Kendrick D, et al. Cost-effectiveness of a day hospital falls prevention programme for screened community-dwelling older people at high risk of falls. Age Ageing. 2010;39(6):710–716. doi: 10.1093/ageing/afq108.
    1. McLean K, Day L, Dalton A. Economic evaluation of a group-based exercise program for falls prevention among the older community-dwelling population. BMC Geriatr. 2015;15:33. doi: 10.1186/s12877-015-0028-x.
    1. Robertson MC, Gardner MM, Devlin N, McGee R, Campbell AJ. Effectiveness and economic evaluation of a nurse delivered home exercise programme to prevent falls. 2: controlled trial in multiple centres. BMJ. 2001;322(7288):701–704. doi: 10.1136/bmj.322.7288.701.
    1. Church J, Goodall S, Norman R, Haas M. An economic evaluation of community and residential aged care falls prevention strategies in NSW. New South Wales public health bulletin. 2011;22(3–4):60–68. doi: 10.1071/NB10051.
    1. Markle-Reid M, Browne G, Gafni A, Roberts J, Weir R, Thabane L, et al. The effects and costs of a multifactorial and interdisciplinary team approach to falls prevention for older home care clients 'at risk' for falling: a randomized controlled trial. Canadian Journal on Aging. 2010;29(1):139–161. doi: 10.1017/S0714980809990377.
    1. Registered Nurses’ Association of Ontario. Nursing best practice guideline: Prevention of fall injuries in the older adult. Toronto, Ontario, Canada; 2011.
    1. Browne G, Gafni A, Roberts J. Approach to the measurement of resource use and costs (working paper S06–01) Hamilton, Ontario, Canada: McMaster University, System-Linked Research Unit on Health and Social Service Utilization; 2006.
    1. Browne G, Roberts J, Byrne C, Gafni A, Weir R, Majumdar B. The costs and effects of addressing the needs of vulnerable populations: results of 10 years of research. Can J Nurs Res. 2001;33:65–76.
    1. Browne G, Roberts J, Gafni A, Byrne C, Weir R, Majumdar B, et al. Economic evaluations of community-based care: lessons from twelve studies in Ontario. J Eval Clin Pract. 1999;5:367–385. doi: 10.1046/j.1365-2753.1999.00191.x.
    1. Hoch J, Briggs A, Willan A. Something old, something new, something borrowed, something blue: a framework for the marriage of health econometrics and cost-effectiveness analysis. Health Econ. 2002;11:415–430. doi: 10.1002/hec.678.
    1. Drummond M, Sculpher M, Torrance G, O'Brien B, Stoddart G. Methods for the economic evaluation of health care programmes. 3. New York: Oxford University Press; 2005.
    1. Fenwick E, O'Brien B, Briggs A. Cost-effectiveness acceptability curves – facts, fallacies, and frequently asked questions. Health Econ. 2004;13:405–415. doi: 10.1002/hec.903.
    1. Hoch J, Rockx M, Krahn A. Using the net benefit regression framework to construct cost-effectiveness acceptability curves: an example using data from a trial of external loop recorders versus Holter monitoring for ambulatory monitoring of "community acquired" syncope. BMC Health Services Research. 2006;(6)68.
    1. Fletcher PC, Hirdes JP. Risk factors for falling among community-based seniors using home care services. J Gerontol Ser A Biol Med Sci. 2002;57(8):M504–MM10. doi: 10.1093/gerona/57.8.M504.
    1. Society AG, Society G. American Academy of Orthopaedic Surgeons Panel on Falls Prevention. Guideline for the prevention of falls in older persons. J Am Geriatr Soc. 2001;49(5):664–672. doi: 10.1046/j.1532-5415.2001.49115.x.
    1. Soriano TA, DeCherrie LV, Thomas DC. Falls in the community-dwelling older adult: a review for primary-care providers. Clin Interv Aging. 2007;2(4):545.
    1. Stevens JA. Falls among older adults—risk factors and prevention strategies. J Saf Res. 2005;36(4):409–411. doi: 10.1016/j.jsr.2005.08.001.
    1. Briggs AH, O'Brien BJ. The death of cost-minimization analysis? Health Econ. 2001;10(2):179–184. doi: 10.1002/hec.584.
    1. Gallagher E, Brunt H. Head over heels: impact of a health promotion program to reduce falls in the elderly. Canadian Journal on Aging. 1996;15(1):84–96. doi: 10.1017/S0714980800013301.
    1. Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council of Canada, Social Sciences and Humanities Research Council of Canada. Tri-council policy statement: Ethical conduct for research involving humans. 1998 (with 2000, 2002 and 2005 amendments) [Available from: .

Source: PubMed

3
Iratkozz fel