Seroprevalence of and risk factors for HIV-1 infection among South American men who have sex with men

C T Bautista, J L Sanchez, S M Montano, V A Laguna-Torres, J R Lama, J L Sanchez, L Kusunoki, H Manrique, J Acosta, O Montoya, A M Tambare, M M Avila, J Viñoles, N Aguayo, J G Olson, J K Carr, C T Bautista, J L Sanchez, S M Montano, V A Laguna-Torres, J R Lama, J L Sanchez, L Kusunoki, H Manrique, J Acosta, O Montoya, A M Tambare, M M Avila, J Viñoles, N Aguayo, J G Olson, J K Carr

Abstract

Objectives: Sex among men constitutes an important route of transmission for HIV type 1 (HIV-1) in Latin America. Seeking better understanding of risk behaviours in this region, we determined the seroprevalence, potential risk factors, and geographic distribution of HIV-1 among groups of men who have sex with men (MSM).

Methods: Seroepidemiological, cross sectional studies of 13,847 MSM were conducted in seven countries of South America during the years 1999-2002. Volunteers were recruited in city venues and streets where anonymous questionnaires and blood samples were obtained. HIV-1 infection was determined by enzyme linked immunosorbent assay (ELISA) screening and western blot (WB) confirmatory tests.

Results: HIV-1 seroprevalence varied widely (overall 12.3%, range 11.0%-20.6%). The highest HIV-1 seroprevalence was noted in Bolivia (20.6%) and the lowest in Peru (11.0%). Predictors of HIV-1 infection varied among countries; however, a history of previous sexually transmitted disease (STD) was associated with a consistent increased risk (ORs=1.9-2.9, AORs=1.8-2.7). Multiple weekly sexual contacts was found to represent a secondary risk factor in Ecuador, Peru, and Argentina (ORs=1.6-2.9, AORs=1.6-3.1), whereas use of drugs such as cocaine was found to increase risk in Bolivia, Uruguay, and Paraguay (ORs=2.5-6.5, AORs=2.6-6.1).

Conclusion: The results of this study illustrate an elevated HIV-1 seroprevalence among MSM participants from Andean countries. A previous STD history and multiple partners predicted HIV-1 infection in the seven countries of South America. In Southern Cone countries, HIV-1 infection was also associated with use of illegal drugs such as cocaine.

References

    1. JAMA. 2000 Jul 12;284(2):198-204
    1. Br Med Bull. 1998;54(2):369-81
    1. Am J Public Health. 2001 Jun;91(6):907-14
    1. Sex Transm Infect. 2002 Feb;78(1):26-30
    1. AIDS Care. 2002 Jun;14(3):335-41
    1. AIDS Res Hum Retroviruses. 2002 Dec 10;18(18):1339-50
    1. AIDS. 2002 Dec;16 Suppl 3:S23-33
    1. AIDS. 2002 Dec;16 Suppl 3:S34-41
    1. Int J Infect Dis. 2002 Dec;6(4):259-65
    1. Am J Trop Med Hyg. 2003 Jun;68(6):716-20
    1. Int J Epidemiol. 2003 Oct;32(5):735-40
    1. Sex Transm Dis. 2004 Apr;31(4):201-4
    1. Am J Epidemiol. 1982 Jan;115(1):92-106
    1. AIDS. 1996 Feb;10(2):201-6
    1. Am J Public Health. 2001 Jun;91(6):883-8

Source: PubMed

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