Maturational Patterns of Systolic Ventricular Deformation Mechanics by Two-Dimensional Speckle-Tracking Echocardiography in Preterm Infants over the First Year of Age
Philip T Levy, Afif El-Khuffash, Meghna D Patel, Colm R Breatnach, Adam T James, Aura A Sanchez, Cristina Abuchabe, Sarah R Rogal, Mark R Holland, Patrick J McNamara, Amish Jain, Orla Franklin, Luc Mertens, Aaron Hamvas, Gautam K Singh, Philip T Levy, Afif El-Khuffash, Meghna D Patel, Colm R Breatnach, Adam T James, Aura A Sanchez, Cristina Abuchabe, Sarah R Rogal, Mark R Holland, Patrick J McNamara, Amish Jain, Orla Franklin, Luc Mertens, Aaron Hamvas, Gautam K Singh
Abstract
Background: The aim of this study was to determine the maturational changes in systolic ventricular strain mechanics by two-dimensional speckle-tracking echocardiography in extremely preterm neonates from birth to 1 year of age and discern the impact of common cardiopulmonary abnormalities on the deformation measures.
Methods: In a prospective multicenter study of 239 extremely preterm infants (<29 weeks gestation at birth), left ventricular (LV) global longitudinal strain (GLS) and global longitudinal systolic strain rate (GLSRs), interventricular septal wall (IVS) GLS and GLSRs, right ventricular (RV) free wall longitudinal strain and strain rate, and segmental longitudinal strain in the RV free wall, LV free wall, and IVS were serially measured on days 1, 2, and 5 to 7, at 32 and 36 weeks postmenstrual age, and at 1 year corrected age (CA). Premature infants who developed bronchopulmonary dysplasia or had echocardiographic findings of pulmonary hypertension were analyzed separately.
Results: In uncomplicated preterm infants (n = 103 [48%]), LV GLS and GLSRs remained unchanged from days 5 to 7 to 1 year CA (P = .60 and P = .59). RV free wall longitudinal strain, RV free wall longitudinal strain rate, and IVS GLS and GLSRs significantly increased over the same time period (P < .01 for all measures). A significant base-to-apex (highest to lowest) segmental longitudinal strain gradient (P < .01) was seen in the RV free wall and a reverse apex-to-base gradient (P < .01) in the LV free wall. In infants with bronchopulmonary dysplasia and/or pulmonary hypertension (n = 119 [51%]), RV free wall longitudinal strain and IVS GLS were significantly lower (P < .01), LV GLS and GLSRs were similar (P = .56), and IVS segmental longitudinal strain persisted as an RV-dominant base-to-apex gradient from 32 weeks postmenstrual age to 1 year CA.
Conclusions: This study tracks the maturational patterns of global and regional deformation by two-dimensional speckle-tracking echocardiography in extremely preterm infants from birth to 1 year CA. The maturational patterns are ventricular specific. Bronchopulmonary dysplasia and pulmonary hypertension leave a negative impact on RV and IVS strain, while LV strain remains stable.
Keywords: Cardiac function; Echocardiography; Prematurity; Strain imaging.
Copyright © 2017 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.
Figures
![Figure 1. Enrollment and follow-up of study…](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/5495609/bin/nihms858550f1.jpg)
![Figure 2. Maturational patterns of Ventricular Deformation…](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/5495609/bin/nihms858550f2a.jpg)
Figure 2. Maturational patterns of Ventricular Deformation…
Figure 2. Maturational patterns of Ventricular Deformation over the first year of age
(A) RV…
Figure 2. Maturational patterns of Ventricular Deformation…
Figure 2. Maturational patterns of Ventricular Deformation over the first year of age
(A) RV…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
- Right and left ventricular interaction in pulmonary hypertension: Insight from velocity vector imaging.Meng H, Chandrasekaran K, Villarraga HR, Shah AA, Kittipovanonth M, Cha SS, Pellikka PA, Seward JB. Meng H, et al. Echocardiography. 2019 May;36(5):877-887. doi: 10.1111/echo.14328. Epub 2019 Apr 15. Echocardiography. 2019. PMID: 30985965
- Right ventricular regional and global systolic function is diminished in patients with pulmonary arterial hypertension: a 2-dimensional ultrasound speckle tracking echocardiography study.Li Y, Xie M, Wang X, Lu Q, Fu M. Li Y, et al. Int J Cardiovasc Imaging. 2013 Mar;29(3):545-51. doi: 10.1007/s10554-012-0114-5. Epub 2012 Sep 6. Int J Cardiovasc Imaging. 2013. PMID: 22956022
- Myocardial strain abnormalities in fetuses with pulmonary atresia and intact ventricular septum.Cohen J, Binka E, Woldu K, Levasseur S, Glickstein J, Freud LR, Chelliah A, Chiu JS, Shah A. Cohen J, et al. Ultrasound Obstet Gynecol. 2019 Apr;53(4):512-519. doi: 10.1002/uog.19183. Epub 2019 Mar 12. Ultrasound Obstet Gynecol. 2019. PMID: 30043402 Free PMC article.
- Assessment of right ventricular systolic function by tissue Doppler echocardiography.Kjærgaard J. Kjærgaard J. Dan Med J. 2012 Mar;59(3):B4409. Dan Med J. 2012. PMID: 22381093 Review.
- Normal ranges of right ventricular systolic and diastolic strain measures in children: a systematic review and meta-analysis.Levy PT, Sanchez Mejia AA, Machefsky A, Fowler S, Holland MR, Singh GK. Levy PT, et al. J Am Soc Echocardiogr. 2014 May;27(5):549-60, e3. doi: 10.1016/j.echo.2014.01.015. Epub 2014 Feb 26. J Am Soc Echocardiogr. 2014. PMID: 24582163 Free PMC article. Review.
- A scoping review of echocardiographic and lung ultrasound biomarkers of bronchopulmonary dysplasia in preterm infants.Martini S, Corsini I, Corvaglia L, Suryawanshi P, Chan B, Singh Y. Martini S, et al. Front Pediatr. 2023 Feb 10;11:1067323. doi: 10.3389/fped.2023.1067323. eCollection 2023. Front Pediatr. 2023. PMID: 36846161 Free PMC article. Review.
- Echocardiographic Reference Ranges of Non-Invasive Myocardial Work Indices in Newborns.Yanase Y, Iwashima S, Takahashi K. Yanase Y, et al. Circ Rep. 2022 Aug 25;4(9):429-438. doi: 10.1253/circrep.CR-22-0045. eCollection 2022 Sep 9. Circ Rep. 2022. PMID: 36120485 Free PMC article.
- Interobserver Agreement and Reference Intervals for Biventricular Myocardial Deformation in Full-Term, Healthy Newborns: A 2D Speckle-Tracking Echocardiography-Based Strain Analysis.Toma D, Toganel R, Fagarasan A, Cucerea M, Gabor-Miklosi D, Cerghit-Paler A, Iurian DR, Gozar H, Moldovan E, Iancu M, Gozar L. Toma D, et al. Int J Environ Res Public Health. 2022 Jul 15;19(14):8620. doi: 10.3390/ijerph19148620. Int J Environ Res Public Health. 2022. PMID: 35886472 Free PMC article.
- Right Atrial Strain in Preterm Infants With a History of Bronchopulmonary Dysplasia.Kang SJ, Jung H, Hwang SJ, Kim HJ. Kang SJ, et al. J Cardiovasc Imaging. 2022 Apr;30(2):112-122. doi: 10.4250/jcvi.2021.0126. J Cardiovasc Imaging. 2022. PMID: 35505500 Free PMC article.
- The association between pulmonary vascular disease and respiratory improvement in infants with type I severe bronchopulmonary dysplasia.Carpenter RJ, Srdanovic N, Rychlik K, Sen SK, Porta NFM, Hamvas AE, Murthy K, Hauck AL. Carpenter RJ, et al. J Perinatol. 2022 Jun;42(6):788-795. doi: 10.1038/s41372-022-01386-6. Epub 2022 Apr 9. J Perinatol. 2022. PMID: 35397644
- Multicenter Study
- Comorbidity
- Echocardiography / methods*
- Female
- Humans
- Infant
- Infant, Extremely Premature*
- Male
- Prospective Studies
- Systole / physiology*
- Ventricular Dysfunction, Left / diagnostic imaging*
- Ventricular Dysfunction, Left / physiopathology*
- Ventricular Dysfunction, Right / diagnostic imaging*
- Ventricular Dysfunction, Right / physiopathology*
- Full Text Sources
- Other Literature Sources
- Medical
- Miscellaneous
NCBI Literature Resources
The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited.
National Library of Medicine
8600 Rockville Pike
Bethesda, MD 20894
![Figure 2. Maturational patterns of Ventricular Deformation…](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/5495609/bin/nihms858550f2b.jpg)
Figure 2. Maturational patterns of Ventricular Deformation…
Figure 2. Maturational patterns of Ventricular Deformation over the first year of age
(A) RV…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
- Right and left ventricular interaction in pulmonary hypertension: Insight from velocity vector imaging.Meng H, Chandrasekaran K, Villarraga HR, Shah AA, Kittipovanonth M, Cha SS, Pellikka PA, Seward JB. Meng H, et al. Echocardiography. 2019 May;36(5):877-887. doi: 10.1111/echo.14328. Epub 2019 Apr 15. Echocardiography. 2019. PMID: 30985965
- Right ventricular regional and global systolic function is diminished in patients with pulmonary arterial hypertension: a 2-dimensional ultrasound speckle tracking echocardiography study.Li Y, Xie M, Wang X, Lu Q, Fu M. Li Y, et al. Int J Cardiovasc Imaging. 2013 Mar;29(3):545-51. doi: 10.1007/s10554-012-0114-5. Epub 2012 Sep 6. Int J Cardiovasc Imaging. 2013. PMID: 22956022
- Myocardial strain abnormalities in fetuses with pulmonary atresia and intact ventricular septum.Cohen J, Binka E, Woldu K, Levasseur S, Glickstein J, Freud LR, Chelliah A, Chiu JS, Shah A. Cohen J, et al. Ultrasound Obstet Gynecol. 2019 Apr;53(4):512-519. doi: 10.1002/uog.19183. Epub 2019 Mar 12. Ultrasound Obstet Gynecol. 2019. PMID: 30043402 Free PMC article.
- Assessment of right ventricular systolic function by tissue Doppler echocardiography.Kjærgaard J. Kjærgaard J. Dan Med J. 2012 Mar;59(3):B4409. Dan Med J. 2012. PMID: 22381093 Review.
- Normal ranges of right ventricular systolic and diastolic strain measures in children: a systematic review and meta-analysis.Levy PT, Sanchez Mejia AA, Machefsky A, Fowler S, Holland MR, Singh GK. Levy PT, et al. J Am Soc Echocardiogr. 2014 May;27(5):549-60, e3. doi: 10.1016/j.echo.2014.01.015. Epub 2014 Feb 26. J Am Soc Echocardiogr. 2014. PMID: 24582163 Free PMC article. Review.
- A scoping review of echocardiographic and lung ultrasound biomarkers of bronchopulmonary dysplasia in preterm infants.Martini S, Corsini I, Corvaglia L, Suryawanshi P, Chan B, Singh Y. Martini S, et al. Front Pediatr. 2023 Feb 10;11:1067323. doi: 10.3389/fped.2023.1067323. eCollection 2023. Front Pediatr. 2023. PMID: 36846161 Free PMC article. Review.
- Echocardiographic Reference Ranges of Non-Invasive Myocardial Work Indices in Newborns.Yanase Y, Iwashima S, Takahashi K. Yanase Y, et al. Circ Rep. 2022 Aug 25;4(9):429-438. doi: 10.1253/circrep.CR-22-0045. eCollection 2022 Sep 9. Circ Rep. 2022. PMID: 36120485 Free PMC article.
- Interobserver Agreement and Reference Intervals for Biventricular Myocardial Deformation in Full-Term, Healthy Newborns: A 2D Speckle-Tracking Echocardiography-Based Strain Analysis.Toma D, Toganel R, Fagarasan A, Cucerea M, Gabor-Miklosi D, Cerghit-Paler A, Iurian DR, Gozar H, Moldovan E, Iancu M, Gozar L. Toma D, et al. Int J Environ Res Public Health. 2022 Jul 15;19(14):8620. doi: 10.3390/ijerph19148620. Int J Environ Res Public Health. 2022. PMID: 35886472 Free PMC article.
- Right Atrial Strain in Preterm Infants With a History of Bronchopulmonary Dysplasia.Kang SJ, Jung H, Hwang SJ, Kim HJ. Kang SJ, et al. J Cardiovasc Imaging. 2022 Apr;30(2):112-122. doi: 10.4250/jcvi.2021.0126. J Cardiovasc Imaging. 2022. PMID: 35505500 Free PMC article.
- The association between pulmonary vascular disease and respiratory improvement in infants with type I severe bronchopulmonary dysplasia.Carpenter RJ, Srdanovic N, Rychlik K, Sen SK, Porta NFM, Hamvas AE, Murthy K, Hauck AL. Carpenter RJ, et al. J Perinatol. 2022 Jun;42(6):788-795. doi: 10.1038/s41372-022-01386-6. Epub 2022 Apr 9. J Perinatol. 2022. PMID: 35397644
- Multicenter Study
- Comorbidity
- Echocardiography / methods*
- Female
- Humans
- Infant
- Infant, Extremely Premature*
- Male
- Prospective Studies
- Systole / physiology*
- Ventricular Dysfunction, Left / diagnostic imaging*
- Ventricular Dysfunction, Left / physiopathology*
- Ventricular Dysfunction, Right / diagnostic imaging*
- Ventricular Dysfunction, Right / physiopathology*
- Full Text Sources
- Other Literature Sources
- Medical
- Miscellaneous
NCBI Literature Resources
The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited.
National Library of Medicine
8600 Rockville Pike
Bethesda, MD 20894
![Figure 2. Maturational patterns of Ventricular Deformation…](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/5495609/bin/nihms858550f2c.jpg)
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
- Right and left ventricular interaction in pulmonary hypertension: Insight from velocity vector imaging.Meng H, Chandrasekaran K, Villarraga HR, Shah AA, Kittipovanonth M, Cha SS, Pellikka PA, Seward JB. Meng H, et al. Echocardiography. 2019 May;36(5):877-887. doi: 10.1111/echo.14328. Epub 2019 Apr 15. Echocardiography. 2019. PMID: 30985965
- Right ventricular regional and global systolic function is diminished in patients with pulmonary arterial hypertension: a 2-dimensional ultrasound speckle tracking echocardiography study.Li Y, Xie M, Wang X, Lu Q, Fu M. Li Y, et al. Int J Cardiovasc Imaging. 2013 Mar;29(3):545-51. doi: 10.1007/s10554-012-0114-5. Epub 2012 Sep 6. Int J Cardiovasc Imaging. 2013. PMID: 22956022
- Myocardial strain abnormalities in fetuses with pulmonary atresia and intact ventricular septum.Cohen J, Binka E, Woldu K, Levasseur S, Glickstein J, Freud LR, Chelliah A, Chiu JS, Shah A. Cohen J, et al. Ultrasound Obstet Gynecol. 2019 Apr;53(4):512-519. doi: 10.1002/uog.19183. Epub 2019 Mar 12. Ultrasound Obstet Gynecol. 2019. PMID: 30043402 Free PMC article.
- Assessment of right ventricular systolic function by tissue Doppler echocardiography.Kjærgaard J. Kjærgaard J. Dan Med J. 2012 Mar;59(3):B4409. Dan Med J. 2012. PMID: 22381093 Review.
- Normal ranges of right ventricular systolic and diastolic strain measures in children: a systematic review and meta-analysis.Levy PT, Sanchez Mejia AA, Machefsky A, Fowler S, Holland MR, Singh GK. Levy PT, et al. J Am Soc Echocardiogr. 2014 May;27(5):549-60, e3. doi: 10.1016/j.echo.2014.01.015. Epub 2014 Feb 26. J Am Soc Echocardiogr. 2014. PMID: 24582163 Free PMC article. Review.
- A scoping review of echocardiographic and lung ultrasound biomarkers of bronchopulmonary dysplasia in preterm infants.Martini S, Corsini I, Corvaglia L, Suryawanshi P, Chan B, Singh Y. Martini S, et al. Front Pediatr. 2023 Feb 10;11:1067323. doi: 10.3389/fped.2023.1067323. eCollection 2023. Front Pediatr. 2023. PMID: 36846161 Free PMC article. Review.
- Echocardiographic Reference Ranges of Non-Invasive Myocardial Work Indices in Newborns.Yanase Y, Iwashima S, Takahashi K. Yanase Y, et al. Circ Rep. 2022 Aug 25;4(9):429-438. doi: 10.1253/circrep.CR-22-0045. eCollection 2022 Sep 9. Circ Rep. 2022. PMID: 36120485 Free PMC article.
- Interobserver Agreement and Reference Intervals for Biventricular Myocardial Deformation in Full-Term, Healthy Newborns: A 2D Speckle-Tracking Echocardiography-Based Strain Analysis.Toma D, Toganel R, Fagarasan A, Cucerea M, Gabor-Miklosi D, Cerghit-Paler A, Iurian DR, Gozar H, Moldovan E, Iancu M, Gozar L. Toma D, et al. Int J Environ Res Public Health. 2022 Jul 15;19(14):8620. doi: 10.3390/ijerph19148620. Int J Environ Res Public Health. 2022. PMID: 35886472 Free PMC article.
- Right Atrial Strain in Preterm Infants With a History of Bronchopulmonary Dysplasia.Kang SJ, Jung H, Hwang SJ, Kim HJ. Kang SJ, et al. J Cardiovasc Imaging. 2022 Apr;30(2):112-122. doi: 10.4250/jcvi.2021.0126. J Cardiovasc Imaging. 2022. PMID: 35505500 Free PMC article.
- The association between pulmonary vascular disease and respiratory improvement in infants with type I severe bronchopulmonary dysplasia.Carpenter RJ, Srdanovic N, Rychlik K, Sen SK, Porta NFM, Hamvas AE, Murthy K, Hauck AL. Carpenter RJ, et al. J Perinatol. 2022 Jun;42(6):788-795. doi: 10.1038/s41372-022-01386-6. Epub 2022 Apr 9. J Perinatol. 2022. PMID: 35397644
- Multicenter Study
- Comorbidity
- Echocardiography / methods*
- Female
- Humans
- Infant
- Infant, Extremely Premature*
- Male
- Prospective Studies
- Systole / physiology*
- Ventricular Dysfunction, Left / diagnostic imaging*
- Ventricular Dysfunction, Left / physiopathology*
- Ventricular Dysfunction, Right / diagnostic imaging*
- Ventricular Dysfunction, Right / physiopathology*
- Full Text Sources
- Other Literature Sources
- Medical
- Miscellaneous
NCBI Literature Resources
The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited.
National Library of Medicine
8600 Rockville Pike
Bethesda, MD 20894
![Figure 3. Left and right ventricle strain…](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/5495609/bin/nihms858550f3a.jpg)
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
- Right and left ventricular interaction in pulmonary hypertension: Insight from velocity vector imaging.Meng H, Chandrasekaran K, Villarraga HR, Shah AA, Kittipovanonth M, Cha SS, Pellikka PA, Seward JB. Meng H, et al. Echocardiography. 2019 May;36(5):877-887. doi: 10.1111/echo.14328. Epub 2019 Apr 15. Echocardiography. 2019. PMID: 30985965
- Right ventricular regional and global systolic function is diminished in patients with pulmonary arterial hypertension: a 2-dimensional ultrasound speckle tracking echocardiography study.Li Y, Xie M, Wang X, Lu Q, Fu M. Li Y, et al. Int J Cardiovasc Imaging. 2013 Mar;29(3):545-51. doi: 10.1007/s10554-012-0114-5. Epub 2012 Sep 6. Int J Cardiovasc Imaging. 2013. PMID: 22956022
- Myocardial strain abnormalities in fetuses with pulmonary atresia and intact ventricular septum.Cohen J, Binka E, Woldu K, Levasseur S, Glickstein J, Freud LR, Chelliah A, Chiu JS, Shah A. Cohen J, et al. Ultrasound Obstet Gynecol. 2019 Apr;53(4):512-519. doi: 10.1002/uog.19183. Epub 2019 Mar 12. Ultrasound Obstet Gynecol. 2019. PMID: 30043402 Free PMC article.
- Assessment of right ventricular systolic function by tissue Doppler echocardiography.Kjærgaard J. Kjærgaard J. Dan Med J. 2012 Mar;59(3):B4409. Dan Med J. 2012. PMID: 22381093 Review.
- Normal ranges of right ventricular systolic and diastolic strain measures in children: a systematic review and meta-analysis.Levy PT, Sanchez Mejia AA, Machefsky A, Fowler S, Holland MR, Singh GK. Levy PT, et al. J Am Soc Echocardiogr. 2014 May;27(5):549-60, e3. doi: 10.1016/j.echo.2014.01.015. Epub 2014 Feb 26. J Am Soc Echocardiogr. 2014. PMID: 24582163 Free PMC article. Review.
- A scoping review of echocardiographic and lung ultrasound biomarkers of bronchopulmonary dysplasia in preterm infants.Martini S, Corsini I, Corvaglia L, Suryawanshi P, Chan B, Singh Y. Martini S, et al. Front Pediatr. 2023 Feb 10;11:1067323. doi: 10.3389/fped.2023.1067323. eCollection 2023. Front Pediatr. 2023. PMID: 36846161 Free PMC article. Review.
- Echocardiographic Reference Ranges of Non-Invasive Myocardial Work Indices in Newborns.Yanase Y, Iwashima S, Takahashi K. Yanase Y, et al. Circ Rep. 2022 Aug 25;4(9):429-438. doi: 10.1253/circrep.CR-22-0045. eCollection 2022 Sep 9. Circ Rep. 2022. PMID: 36120485 Free PMC article.
- Interobserver Agreement and Reference Intervals for Biventricular Myocardial Deformation in Full-Term, Healthy Newborns: A 2D Speckle-Tracking Echocardiography-Based Strain Analysis.Toma D, Toganel R, Fagarasan A, Cucerea M, Gabor-Miklosi D, Cerghit-Paler A, Iurian DR, Gozar H, Moldovan E, Iancu M, Gozar L. Toma D, et al. Int J Environ Res Public Health. 2022 Jul 15;19(14):8620. doi: 10.3390/ijerph19148620. Int J Environ Res Public Health. 2022. PMID: 35886472 Free PMC article.
- Right Atrial Strain in Preterm Infants With a History of Bronchopulmonary Dysplasia.Kang SJ, Jung H, Hwang SJ, Kim HJ. Kang SJ, et al. J Cardiovasc Imaging. 2022 Apr;30(2):112-122. doi: 10.4250/jcvi.2021.0126. J Cardiovasc Imaging. 2022. PMID: 35505500 Free PMC article.
- The association between pulmonary vascular disease and respiratory improvement in infants with type I severe bronchopulmonary dysplasia.Carpenter RJ, Srdanovic N, Rychlik K, Sen SK, Porta NFM, Hamvas AE, Murthy K, Hauck AL. Carpenter RJ, et al. J Perinatol. 2022 Jun;42(6):788-795. doi: 10.1038/s41372-022-01386-6. Epub 2022 Apr 9. J Perinatol. 2022. PMID: 35397644
- Multicenter Study
- Comorbidity
- Echocardiography / methods*
- Female
- Humans
- Infant
- Infant, Extremely Premature*
- Male
- Prospective Studies
- Systole / physiology*
- Ventricular Dysfunction, Left / diagnostic imaging*
- Ventricular Dysfunction, Left / physiopathology*
- Ventricular Dysfunction, Right / diagnostic imaging*
- Ventricular Dysfunction, Right / physiopathology*
- Full Text Sources
- Other Literature Sources
- Medical
- Miscellaneous
NCBI Literature Resources
The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited.
National Library of Medicine
8600 Rockville Pike
Bethesda, MD 20894
![Figure 3. Left and right ventricle strain…](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/5495609/bin/nihms858550f3b.jpg)
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
- Right and left ventricular interaction in pulmonary hypertension: Insight from velocity vector imaging.Meng H, Chandrasekaran K, Villarraga HR, Shah AA, Kittipovanonth M, Cha SS, Pellikka PA, Seward JB. Meng H, et al. Echocardiography. 2019 May;36(5):877-887. doi: 10.1111/echo.14328. Epub 2019 Apr 15. Echocardiography. 2019. PMID: 30985965
- Right ventricular regional and global systolic function is diminished in patients with pulmonary arterial hypertension: a 2-dimensional ultrasound speckle tracking echocardiography study.Li Y, Xie M, Wang X, Lu Q, Fu M. Li Y, et al. Int J Cardiovasc Imaging. 2013 Mar;29(3):545-51. doi: 10.1007/s10554-012-0114-5. Epub 2012 Sep 6. Int J Cardiovasc Imaging. 2013. PMID: 22956022
- Myocardial strain abnormalities in fetuses with pulmonary atresia and intact ventricular septum.Cohen J, Binka E, Woldu K, Levasseur S, Glickstein J, Freud LR, Chelliah A, Chiu JS, Shah A. Cohen J, et al. Ultrasound Obstet Gynecol. 2019 Apr;53(4):512-519. doi: 10.1002/uog.19183. Epub 2019 Mar 12. Ultrasound Obstet Gynecol. 2019. PMID: 30043402 Free PMC article.
- Assessment of right ventricular systolic function by tissue Doppler echocardiography.Kjærgaard J. Kjærgaard J. Dan Med J. 2012 Mar;59(3):B4409. Dan Med J. 2012. PMID: 22381093 Review.
- Normal ranges of right ventricular systolic and diastolic strain measures in children: a systematic review and meta-analysis.Levy PT, Sanchez Mejia AA, Machefsky A, Fowler S, Holland MR, Singh GK. Levy PT, et al. J Am Soc Echocardiogr. 2014 May;27(5):549-60, e3. doi: 10.1016/j.echo.2014.01.015. Epub 2014 Feb 26. J Am Soc Echocardiogr. 2014. PMID: 24582163 Free PMC article. Review.
- A scoping review of echocardiographic and lung ultrasound biomarkers of bronchopulmonary dysplasia in preterm infants.Martini S, Corsini I, Corvaglia L, Suryawanshi P, Chan B, Singh Y. Martini S, et al. Front Pediatr. 2023 Feb 10;11:1067323. doi: 10.3389/fped.2023.1067323. eCollection 2023. Front Pediatr. 2023. PMID: 36846161 Free PMC article. Review.
- Echocardiographic Reference Ranges of Non-Invasive Myocardial Work Indices in Newborns.Yanase Y, Iwashima S, Takahashi K. Yanase Y, et al. Circ Rep. 2022 Aug 25;4(9):429-438. doi: 10.1253/circrep.CR-22-0045. eCollection 2022 Sep 9. Circ Rep. 2022. PMID: 36120485 Free PMC article.
- Interobserver Agreement and Reference Intervals for Biventricular Myocardial Deformation in Full-Term, Healthy Newborns: A 2D Speckle-Tracking Echocardiography-Based Strain Analysis.Toma D, Toganel R, Fagarasan A, Cucerea M, Gabor-Miklosi D, Cerghit-Paler A, Iurian DR, Gozar H, Moldovan E, Iancu M, Gozar L. Toma D, et al. Int J Environ Res Public Health. 2022 Jul 15;19(14):8620. doi: 10.3390/ijerph19148620. Int J Environ Res Public Health. 2022. PMID: 35886472 Free PMC article.
- Right Atrial Strain in Preterm Infants With a History of Bronchopulmonary Dysplasia.Kang SJ, Jung H, Hwang SJ, Kim HJ. Kang SJ, et al. J Cardiovasc Imaging. 2022 Apr;30(2):112-122. doi: 10.4250/jcvi.2021.0126. J Cardiovasc Imaging. 2022. PMID: 35505500 Free PMC article.
- The association between pulmonary vascular disease and respiratory improvement in infants with type I severe bronchopulmonary dysplasia.Carpenter RJ, Srdanovic N, Rychlik K, Sen SK, Porta NFM, Hamvas AE, Murthy K, Hauck AL. Carpenter RJ, et al. J Perinatol. 2022 Jun;42(6):788-795. doi: 10.1038/s41372-022-01386-6. Epub 2022 Apr 9. J Perinatol. 2022. PMID: 35397644
- Multicenter Study
- Comorbidity
- Echocardiography / methods*
- Female
- Humans
- Infant
- Infant, Extremely Premature*
- Male
- Prospective Studies
- Systole / physiology*
- Ventricular Dysfunction, Left / diagnostic imaging*
- Ventricular Dysfunction, Left / physiopathology*
- Ventricular Dysfunction, Right / diagnostic imaging*
- Ventricular Dysfunction, Right / physiopathology*
- Full Text Sources
- Other Literature Sources
- Medical
- Miscellaneous
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![Figure 3. Left and right ventricle strain…](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/5495609/bin/nihms858550f3c.jpg)
Figure 3. Left and right ventricle strain…
Figure 3. Left and right ventricle strain and systolic strain rate in infants with and…
- Right and left ventricular interaction in pulmonary hypertension: Insight from velocity vector imaging.Meng H, Chandrasekaran K, Villarraga HR, Shah AA, Kittipovanonth M, Cha SS, Pellikka PA, Seward JB. Meng H, et al. Echocardiography. 2019 May;36(5):877-887. doi: 10.1111/echo.14328. Epub 2019 Apr 15. Echocardiography. 2019. PMID: 30985965
- Right ventricular regional and global systolic function is diminished in patients with pulmonary arterial hypertension: a 2-dimensional ultrasound speckle tracking echocardiography study.Li Y, Xie M, Wang X, Lu Q, Fu M. Li Y, et al. Int J Cardiovasc Imaging. 2013 Mar;29(3):545-51. doi: 10.1007/s10554-012-0114-5. Epub 2012 Sep 6. Int J Cardiovasc Imaging. 2013. PMID: 22956022
- Myocardial strain abnormalities in fetuses with pulmonary atresia and intact ventricular septum.Cohen J, Binka E, Woldu K, Levasseur S, Glickstein J, Freud LR, Chelliah A, Chiu JS, Shah A. Cohen J, et al. Ultrasound Obstet Gynecol. 2019 Apr;53(4):512-519. doi: 10.1002/uog.19183. Epub 2019 Mar 12. Ultrasound Obstet Gynecol. 2019. PMID: 30043402 Free PMC article.
- Assessment of right ventricular systolic function by tissue Doppler echocardiography.Kjærgaard J. Kjærgaard J. Dan Med J. 2012 Mar;59(3):B4409. Dan Med J. 2012. PMID: 22381093 Review.
- Normal ranges of right ventricular systolic and diastolic strain measures in children: a systematic review and meta-analysis.Levy PT, Sanchez Mejia AA, Machefsky A, Fowler S, Holland MR, Singh GK. Levy PT, et al. J Am Soc Echocardiogr. 2014 May;27(5):549-60, e3. doi: 10.1016/j.echo.2014.01.015. Epub 2014 Feb 26. J Am Soc Echocardiogr. 2014. PMID: 24582163 Free PMC article. Review.
- A scoping review of echocardiographic and lung ultrasound biomarkers of bronchopulmonary dysplasia in preterm infants.Martini S, Corsini I, Corvaglia L, Suryawanshi P, Chan B, Singh Y. Martini S, et al. Front Pediatr. 2023 Feb 10;11:1067323. doi: 10.3389/fped.2023.1067323. eCollection 2023. Front Pediatr. 2023. PMID: 36846161 Free PMC article. Review.
- Echocardiographic Reference Ranges of Non-Invasive Myocardial Work Indices in Newborns.Yanase Y, Iwashima S, Takahashi K. Yanase Y, et al. Circ Rep. 2022 Aug 25;4(9):429-438. doi: 10.1253/circrep.CR-22-0045. eCollection 2022 Sep 9. Circ Rep. 2022. PMID: 36120485 Free PMC article.
- Interobserver Agreement and Reference Intervals for Biventricular Myocardial Deformation in Full-Term, Healthy Newborns: A 2D Speckle-Tracking Echocardiography-Based Strain Analysis.Toma D, Toganel R, Fagarasan A, Cucerea M, Gabor-Miklosi D, Cerghit-Paler A, Iurian DR, Gozar H, Moldovan E, Iancu M, Gozar L. Toma D, et al. Int J Environ Res Public Health. 2022 Jul 15;19(14):8620. doi: 10.3390/ijerph19148620. Int J Environ Res Public Health. 2022. PMID: 35886472 Free PMC article.
- Right Atrial Strain in Preterm Infants With a History of Bronchopulmonary Dysplasia.Kang SJ, Jung H, Hwang SJ, Kim HJ. Kang SJ, et al. J Cardiovasc Imaging. 2022 Apr;30(2):112-122. doi: 10.4250/jcvi.2021.0126. J Cardiovasc Imaging. 2022. PMID: 35505500 Free PMC article.
- The association between pulmonary vascular disease and respiratory improvement in infants with type I severe bronchopulmonary dysplasia.Carpenter RJ, Srdanovic N, Rychlik K, Sen SK, Porta NFM, Hamvas AE, Murthy K, Hauck AL. Carpenter RJ, et al. J Perinatol. 2022 Jun;42(6):788-795. doi: 10.1038/s41372-022-01386-6. Epub 2022 Apr 9. J Perinatol. 2022. PMID: 35397644
- Multicenter Study
- Comorbidity
- Echocardiography / methods*
- Female
- Humans
- Infant
- Infant, Extremely Premature*
- Male
- Prospective Studies
- Systole / physiology*
- Ventricular Dysfunction, Left / diagnostic imaging*
- Ventricular Dysfunction, Left / physiopathology*
- Ventricular Dysfunction, Right / diagnostic imaging*
- Ventricular Dysfunction, Right / physiopathology*
- Full Text Sources
- Other Literature Sources
- Medical
- Miscellaneous
![Figure 3. Left and right ventricle strain…](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/5495609/bin/nihms858550f3d.jpg)
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