A Randomized, Double-Blind, Placebo Controlled Trial to Determine the Effectiveness a Polyphenolic Extract ( Hibiscus sabdariffa and Lippia citriodora) in the Reduction of Body Fat Mass in Healthy Subjects

Javier Marhuenda, Silvia Perez, Desirée Victoria-Montesinos, María Salud Abellán, Nuria Caturla, Jonathan Jones, Javier López-Román, Javier Marhuenda, Silvia Perez, Desirée Victoria-Montesinos, María Salud Abellán, Nuria Caturla, Jonathan Jones, Javier López-Román

Abstract

: The location and quantity of body fat determine the health risks, limiting people with obesity. Recently, polyphenols have attracted the attention of the scientific community because of their potential use for the reduction of obesity. A proprietary formula comprised of a blend of Lippia citriodora and Hibiscus sabdariffa has been recognized for its high content of polyphenols, powerful antioxidant molecules that may prevent weight gain and could be helpful for the treatment of obesity, as proven previously by in vivo models. The aim of the present study is to determine if the supplementation with Lippia citriodora and Hibiscus sabdariffa is useful for the treatment of obesity and/or weight control in subjects without a controlled diet. The intake of the extract for 84 days reduced body weight, the body mass index, and the fat mass measured with both bioimpedance and densitometry. This decrease in fat mass was observed to a greater extent, being significant, in the fat mass of the trunk (chest and torso).

Keywords: Hibiscus sabdariffa; Lippia citriodora; obesity; polyphenols.

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Graphic representation of the study. HS-LC, Hibiscus sabdariffa and Lippia citriodora
Figure 2
Figure 2
Weight and BMI evolution along the study. * Means statistically significant differences.
Figure 3
Figure 3
Body composition evolution along the study, measured by bioimpedance. * Means statistically significant differences.
Figure 4
Figure 4
Body composition evolution along the study, measured by densitometry. * Means statistically significant differences.
Figure 5
Figure 5
Physical activity EVOLUTION along the study. MET, metabolic equivalent of task.

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