Prevention of Anxiety and Depression in Swedish School Children: a Cluster-Randomized Effectiveness Study

Johan Ahlen, Timo Hursti, Lindsey Tanner, Zelal Tokay, Ata Ghaderi, Johan Ahlen, Timo Hursti, Lindsey Tanner, Zelal Tokay, Ata Ghaderi

Abstract

Our study aimed at evaluating FRIENDS for Life, an intervention to prevent anxiety and depression in Swedish school children. A total of 695 children between the ages of 8 and 11 were recruited from 17 schools in Stockholm, Sweden, and cluster-randomized to either the intervention or control group. Teachers in the intervention group received a full day of training and administered FRIENDS for Life in their classrooms. We assessed the children's anxiety and depressive symptoms, general mental health, and academic performance at pre- and post-intervention as well as at the 12-month follow-up. A multi-informant approach was used with data collected from children, parents, and teachers. Assessment was done with the Spence Children's Anxiety Scale, Children's Depression Inventory, and the Strengths and Difficulties Questionnaire. Children's baseline symptoms, gender, and age as well as their teacher's use of supervision were examined as moderators of effect. Our study found no short- or long-term effects of the intervention for any outcome with regard to the entire sample. We found an enhanced effect of the intervention regarding children with elevated depressive symptoms at baseline. We found a decrease in anxiety symptoms among children whose teachers attended a larger number of supervision sessions, compared to children whose teachers attended fewer supervised sessions or the control group. Mediation analyses showed that this effect was driven by change in the last phase of the intervention, suggesting that supervision might play an important role in enhancing teachers' ability to administer the intervention effectively.

Keywords: Anxiety; Depression; School children; Universal prevention.

Conflict of interest statement

Conflict of Interest

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Flow of participants through each stage of the trial

References

    1. Ahlen J, Lenhard F, Ghaderi A. Universal prevention for anxiety and depressive symptoms in children: A meta-analysis of randomized and cluster-randomized trials. The Journal of Primary Prevention. 2015;36:387–403. doi: 10.1007/s10935-015-0405-4.
    1. Allgaier AK, Frühe B, Pietsch K, Saravo B, Baethmann M, Schulte-Körne G. Is the children’s depression inventory short version a valid screening tool in pediatric care? A comparison to its full-length version. Journal of Psychosomatic Research. 2012;73:369–374. doi: 10.1016/j.jpsychores.2012.08.016.
    1. Barrett P. Friends for life: Group leaders’ manual for children. 5. Brisbane: Barrett Research Resources Pty Ltd; 2010.
    1. Barrett P, Turner C. Prevention of anxiety symptoms in primary school children: Preliminary results from a universal school-based trial. British Journal of Clinical Psychology. 2001;40:399–410. doi: 10.1348/014466501163887.
    1. Barrett PM, Farrell LJ, Ollendick TH, Dadds M. Long-term outcomes of an Australian universal prevention trial of anxiety and depression symptoms in children and youth: An evaluation of the friends program. Journal of Clinical Child & Adolescent Psychology. 2006;35:403–411. doi: 10.1207/s15374424jccp3503_5.
    1. Bienvenu OJ, Ginsburg GS. Prevention of anxiety disorders. International Review of Psychiatry. 2007;19:647–654. doi: 10.1080/09540260701797837.
    1. Birmaher B, Ryan ND, Williamson DE, Brent DA, Kaufman J. Childhood and adolescent depression: A review of the past 10 years. Part II. Journal of the American Academy of Child and Adolescent Psychiatry. 1996;35:1575–1583. doi: 10.1097/00004583-199612000-00008.
    1. Bittner A, Egger HL, Erkanli A, Costello EJ, Foley DL, Angold A. What do childhood anxiety disorders predict? Journal of Child Psychology and Psychiatry. 2007;48:1174–1183. doi: 10.1111/j.1469-7610.2007.01812.x.
    1. Costello EJ, Mustillo S, Erkanli A, Keeler G, Angold A. Prevalence and development of psychiatric disorders in childhood and adolescence. Archives of General Psychiatry. 2003;60:837–844. doi: 10.1001/archpsyc.60.8.837.
    1. Curran GM, Bauer M, Mittman B, Pyne JM, Stetler C. Effectiveness-implementation hybrid designs: Combining elements of clinical effectiveness and implementation research to enhance public health impact. Medical Care. 2012;50:217. doi: 10.1097/MLR.0b013e3182408812.
    1. Donovan CL, Spence SH. Prevention of childhood anxiety disorders. Clinical Psychology Review. 2000;20:509–531. doi: 10.1016/S0272-7358(99)00040-9.
    1. Essau CA, Sasagawa S, Anastassiou-Hadjicharalambous X, Guzmán BO, Ollendick TH. Psychometric properties of the Spence Child Anxiety Scale with adolescents from five European countries. Journal of Anxiety Disorders. 2011;25:19–27. doi: 10.1016/j.janxdis.2010.07.001.
    1. Essau CA, Conradt J, Sasagawa S, Ollendick TH. Prevention of anxiety symptoms in children: Results from a universal school-based trial. Behavior Therapy. 2012;43:450–464. doi: 10.1016/j.beth.2011.08.003.
    1. Fisak BJ, Jr, Richard D, Mann A. The prevention of child and adolescent anxiety: A meta-analytic review. Prevention Science. 2011;12:255–268. doi: 10.1007/s11121-011-0210-0.
    1. Goodman R. The strengths and difficulties questionnaire: A research note. Journal of Child Psychology and Psychiatry. 1997;38:581–586. doi: 10.1111/j.1469-7610.1997.tb01545.x.
    1. Goodman R, Scott S. Comparing the strengths and difficulties questionnaire and the child behaviour checklist: Is small beautiful? Journal of Abnormal Child Psychology. 1999;27:17–24. doi: 10.1023/A:1022658222914.
    1. Heck RH, Thomas S, Tabata L. Multilevel and longitudinal modeling with IBM SPSS. 2. Hoboken: Taylor and Francis; 2013.
    1. Hemming K, Girling AJ, Sitch AJ, Marsh J, Lilford RJ. Sample size calculations for cluster randomised controlled trials with a fixed number of clusters. BMC Medical Research Methodology. 2011;11:102. doi: 10.1186/1471-2288-11-102.
    1. Iizuka, C. A., Barrett, P., & Morris, K. (2013). Anxiety Prevention in School Children and Adolescents: The FRIENDS Program. In C. A., & Ollendick, T. H. (Eds.), The Wiley-Blackwell handbook of the treatment of childhood and adolescent anxiety (pp. 519–543). Chichester: John Wiley & Sons.
    1. Imai K, Keele L, Tingley D. A general approach to causal mediation analysis. Psychological Methods. 2010;15:309–334. doi: 10.1037/a0020761.
    1. Kovacs M. Children’s depression inventory (CDI). Technical manual update. North Tonawanda: Multi-Health Systems; 2003.
    1. Lowry-Webster HM, Barrett PM, Lock S. A universal prevention trial of anxiety symptomology during childhood: Results at 1-year follow-up. Behaviour Change. 2003;20:25–43. doi: 10.1375/bech.20.1.25.24843.
    1. Miller LD, Laye-Gindhu A, Bennett JL, Liu Y, Gold S, March JS, et al. An effectiveness study of a culturally enriched school-based CBT anxiety prevention program. Journal of Clinical Child and Adolescent Psychology. 2011;40:618–629. doi: 10.1080/15374416.2011.581619.
    1. Miller LD, Laye-Gindhu A, Liu Y, March JS, Thordarson DS, Garland EJ. Evaluation of a preventive intervention for child anxiety in two randomized attention-control school trials. Behaviour Research and Therapy. 2011;49:315–323. doi: 10.1016/j.brat.2011.02.006.
    1. Nauta MH, Scholing A, Rapee RM, Abbott M, Spence SH, Waters A. A parent-report measure of children’s anxiety: Psychometric properties and comparison child-report in a clinic and normal sample. Behaviour Research and Therapy. 2004;42:813–839. doi: 10.1016/S0005-7967(03)00200-6.
    1. R Core Team (2015). R: A language and environment for statistical computing. Available at .
    1. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, et al. The Mini International Neuropsychiatric Interview (MINI): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. Journal of Clinical Psychiatry. 1998;59:22–33.
    1. Sheehan DV, Sheehan KH, Shytle RD, Janavs J, Bannon Y, Rogers JE, et al. Reliability and validity of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID) The Journal of Clinical Psychiatry. 2010;71:313–326. doi: 10.4088/JCP.09m05305whi.
    1. Smedje H, Broman JE, Hetta J, Knorring AH. Psychometric properties of a Swedish version of the “Strength and Difficulties Questionnaire”. European Child & Adolescent Psychiatry. 1999;8:63–70. doi: 10.1007/s007870050086.
    1. Snell T, Knapp M, Healey A, Guglani S, Evans-Lacko S, Fernandez JL, et al. Economic impact of childhood psychiatric disorder on public sector services in Britain: Estimates from national survey data. Journal of Child Psychology and Psychiatry. 2013;54:977–985. doi: 10.1111/jcpp.12055.
    1. Spence SH. A measure of anxiety symptoms among children. Behaviour Research and Therapy. 1998;36:545–566. doi: 10.1016/S0005-7967(98)00034-5.
    1. Spence SH. Spence Children’s Anxiety Scale-Parent Version. Brisbane: University of Queensland; 1999.
    1. Spence, S. H. (2010a). SCAS—Boys Aged 8–11 [PDF file]. Retrieved from .
    1. Spence, S. H. (2010b). SCAS—Girls Aged 8–11 [PDF file]. Retrieved from .
    1. Stallard P, Skryabina E, Taylor G, Phillips R, Daniels H, Anderson R, Simpson N. Classroom-based cognitive behaviour therapy (FRIENDS): A cluster randomised controlled trial to Prevent Anxiety in Children through Education in Schools (PACES) The Lancet Psychiatry. 2014;1:185–192. doi: 10.1016/S2215-0366(14)70244-5.
    1. Stice E, Shaw H, Bohon C, Marti CN, Rohde P. A meta-analytic review of depression prevention programs for children and adolescents: Factors that predict magnitude of intervention effects. Journal of Consulting and Clinical Psychology. 2009;77:486–503. doi: 10.1037/a0015168.
    1. Teubert D, Pinquart M. A meta-analytic review on the prevention of symptoms of anxiety in children and adolescents. Journal of Anxiety Disorders. 2011;25:1046–1059. doi: 10.1016/j.janxdis.2011.07.001.
    1. Valeri L, VanderWeele TJ. Mediation analysis allowing for exposure–mediator interactions and causal interpretation: Theoretical assumptions and implementation with SAS and SPSS macros. Psychological Methods. 2013;18:137. doi: 10.1037/a0031034.
    1. Van der Leeden R, Meijer E, Busing FM. Resampling multilevel models. In handbook of multilevel analysis. New York: Springer; 2008. pp. 401–433.

Source: PubMed

3
Iratkozz fel