Real-time ultrasound-guided stellate ganglion block for migraine: an observational study

Jiawei Hou, Shaofeng Pu, Xingguo Xu, Zhiqiang Lu, Junzhen Wu, Jiawei Hou, Shaofeng Pu, Xingguo Xu, Zhiqiang Lu, Junzhen Wu

Abstract

Objective: To observe whether ultrasound-guided stellate ganglion block (SGB) can effectively relieve migraine pain and improve the quality of migraine patients' life.

Methods: 81 patients with migraines were enrolled in this study. The patients received SGB with 6 ml of 0.15% ropivacaine once every week for four times. Migraine was assessed with the Migraine Disability Assessment Scale (MIDAS) at baseline and three-months follow-up (Tm). The numerical rating scale (NRS) score at baseline, one day after treatment (Td) and Tm, the frequency of analgesic use in 3 months and the side effects were also recorded at the same time.

Results: The NRS score of migraine subjects decreased significantly from 7.0 (2.0) to 3.0 (1.0) at Td and 2.0 (2.0) at Tm (vs baseline, P < 0.01). The MIDAS total scores were 14.0 (10.5) at baseline and 7.0 (4.5) at Tm (P < 0.001). During the three months, the frequency of analgesic consumption was decreased from 6.2 ± 2.8 to 1.9 ± 1.8. There were no serious side effects.

Conclusions: This study confirmed that ultrasound-guided SGB is an effective method to treat migraines. This technique can reduce pain and disability and then improve the quality of life of patients with migraines.

Keywords: Migraine; Stellate ganglion block (SGB); Ultrasound guidance.

Conflict of interest statement

The authors declare that they have no conflicts of interest.

© 2022. The Author(s).

Figures

Fig. 1
Fig. 1
Ultrasonic exploration of stellate ganglion. A: Patient’s position and placement of ultrasound probe. B: Ultrasound image of the cervical structure during stellate ganglion block.1, thyroid; 2, common carotid artery; 3, internal jugular vein; 4, brachial plexus; 5, vertebral artery; 6, longus colli muscle
Fig. 2
Fig. 2
Stellate ganglion block process. A: The tip of the needle reached the surface of the longus colli muscle and the 5 o’clock position of the carotid artery. B: After administration of ropivacaine, the carotid artery can be seen floating like a balloon in real time under ultrasound, which indicates that the ropivacaine diffuses in the paravertebral space and can effectively block the stellate ganglion. 1, common carotid artery; 2, longus colli muscle; The three arrows indicate the puncture needle, and the two-way arrows indicate that the distance between the common carotid artery and the longus colli muscle is larger than that in Fig. A
Fig. 3
Fig. 3
Flow chart for selecting study population

References

    1. Collaborators GBDMM Global, regional, and national levels of maternal mortality, 1990-2015: a systematic analysis for the global burden of disease study 2015. Lancet. 2016;388:1775–1812.
    1. Silberstein SD. Migraine. Lancet. 2004;363:381–391.
    1. Burch RC, Buse DC, Lipton RB. Migraine: epidemiology, burden, and comorbidity. Neurol Clin. 2019;37:631–649.
    1. Moon S, Lee J, Jeon Y. Bilateral stellate ganglion block for migraine: a case report. Medicine. 2020;99:e20023.
    1. Lynch JH, Mulvaney SW, Kim EH, et al. Effect of stellate ganglion block on specific symptom clusters for treatment of post-traumatic stress disorder. Mil Med. 2016;181:1135–1141.
    1. Park MW, Lee SU, Kwon S, et al. Comparison between the effectiveness of complex decongestive therapy and stellate ganglion block in patients with breast Cancer-related lymphedema: a randomized controlled study. Pain Physician. 2019;22:255–263.
    1. Aeschbach A, Mekhail NA. Common nerve blocks in chronic pain management. Anesthesiology clinics of north. America. 2000;18:429–459.
    1. Slappendel R, Thijssen HO, Crul BJ, et al. The stellate ganglion in magnetic resonance imaging: a quantification of the anatomic variability. Anesthesiology. 1995;83:424–426.
    1. Yu Q, Zheng E, Li X, et al. Ultrasound image guided lateral cervical approach to stellate ganglion block for cervical headache. Neurosci Lett. 2020;735:135139.
    1. Ueshima H. A successful case of stellate ganglion block for difficult therapy of refractory tension headache. J Clin Anesth. 2019;54:149.
    1. Headache classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38:1–211. 10.1177/0333102417738202, .
    1. Stewart WF, Lipton RB, Kolodner KB, et al. Validity of the migraine disability assessment (MIDAS) score in comparison to a diary-based measure in a population sample of migraine sufferers. Pain. 2000;88:41–52.
    1. Lipton RB, Stewart WF, Sawyer J, et al. Clinical utility of an instrument assessing migraine disability: the migraine disability assessment (MIDAS) questionnaire. Headache. 2001;41:854–861.
    1. Yang Y, Song M, Fan Y, et al. Occipital nerve stimulation for migraine: a systematic review. Pain Pract. 2016;16:509–517.
    1. Li W, Diao X, Chen C, et al. Changes in hormones of the hypothalamic-pituitary-gonadal axis in migraine patients. J Clin Neurosci. 2018;50:165–171.
    1. Zhao E, Xie H, Zhang Y. A Nomogram for the prediction of cessation of migraine among patients with patent foramen Ovale after percutaneous closure. Front Neurol. 2020;11:593074.
    1. Hawker GA, Mian S, Kendzerska T, et al. Measures of adult pain: visual analog scale for pain (VAS pain), numeric rating scale for pain (NRS pain), McGill pain questionnaire (MPQ), short-form McGill pain questionnaire (SF-MPQ), chronic pain grade scale (CPGS), short Form-36 bodily pain scale (SF-36 BPS), and measure of intermittent and constant osteoarthritis pain (ICOAP) Arthritis Care Res. 2011;63(Suppl 11):S240–S252.
    1. Singer AB, Buse DC, Seng EK. Behavioral treatments for migraine management: useful at each step of migraine care. Curr Neurol Neurosci Rep. 2015;15:14.
    1. Dach F, Eckeli AL, Ferreira Kdos S, et al. Nerve block for the treatment of headaches and cranial neuralgias - a practical approach. Headache. 2015;55(Suppl 1):59–71.
    1. Allen SM, Mookadam F, Cha SS, et al. Greater occipital nerve block for acute treatment of migraine headache: a large retrospective cohort study. J Am Board Fam Med. 2018;31:211–218.
    1. Li J, Yin Y, Ye L, et al. Pulsed radiofrequency of C2 dorsal root ganglion under ultrasound guidance for chronic migraine: a case report. J Pain Res. 2018;11:1915–1919.
    1. Raposio E, Bertozzi N. Trigger site inactivation for the surgical therapy of occipital migraine and tension-type headache: our experience and review of the literature. Plast Reconstr Surg Glob Open. 2019;7:e2507.
    1. Lehmann LJ, Warfield CA, Bajwa ZH. Migraine headache following stellate ganglion block for reflex sympathetic dystrophy. Headache. 1996;36:335–337.
    1. Pu S, Wu J, Han Q, et al. Ultrasonography-guided radiofrequency ablation for painful stump neuromas to relieve Postamputation pain: a pilot study. J Pain Res. 2020;13:3437–3445.
    1. Pu S, Wu Y, Han Q, et al. Ultrasound-guided Extraforaminal thoracic nerve root block through the midpoint of the inferior articular process and the parietal pleura: a clinical application of thoracic paravertebral nerve block. J Pain Res. 2022;15:533–544.
    1. Lee MH, Kim KY, Song JH, et al. Minimal volume of local anesthetic required for an ultrasound-guided SGB. Pain Med. 2012;13:1381–1388.
    1. Yoo Y, Lee CS, Kim YC, et al. A randomized comparison between 4, 6 and 8 mL of local anesthetic for ultrasound-guided stellate ganglion block. J Clin Med. 2019;8(9):1314. 10.3390/jcm8091314.
    1. Westerhaus MJ, Loewy AD. Central representation of the sympathetic nervous system in the cerebral cortex. Brain Res. 2001;903:117–127.
    1. Makharita MY, Amr YM, El-Bayoumy Y. Effect of early stellate ganglion blockade for facial pain from acute herpes zoster and incidence of postherpetic neuralgia. Pain Physician. 2012;15:467–474.
    1. Lipov EG, Joshi JR, Sanders S, et al. Effects of stellate-ganglion block on hot flushes and night awakenings in survivors of breast cancer: a pilot study. Lancet Oncol. 2008;9:523–532.
    1. Lipov EG, Navaie M, Brown PR, et al. Stellate ganglion block improves refractory post-traumatic stress disorder and associated memory dysfunction: a case report and systematic literature review. Mil Med. 2013;178:e260–e264.
    1. Long R, Zhu Y, Zhou S. Therapeutic role of melatonin in migraine prophylaxis: a systematic review. Medicine. 2019;98:e14099.
    1. Uchida K, Tateda T, Hino H. Novel mechanism of action hypothesized for stellate ganglion block related to melatonin. Med Hypotheses. 2002;59:446–449.
    1. Miano S, Parisi P, Pelliccia A, et al. Melatonin to prevent migraine or tension-type headache in children. Neurol Sci. 2008;29:285–287.
    1. Sherbourne CD, Gonzales R, Goldyne ME, et al. Norepinephrine-induced increase in sympathetic neuron-derived prostaglandins is independent of neuronal release mechanisms. Neurosci Lett. 1992;139:188–190.
    1. Sheridan DC, Laurie A, Pacheco S, et al. Relative effectiveness of dopamine antagonists for pediatric migraine in the emergency department. Pediatr Emerg Care. 2018;34:165–168.
    1. Antonova M, Wienecke T, Olesen J, et al. Prostaglandins in migraine: update. Curr Opin Neurol. 2013;26:269–275.
    1. Stewart WF, Lipton RB, Whyte J, et al. An international study to assess reliability of the migraine disability assessment (MIDAS) score. Neurology. 1999;53:988–994.
    1. Ford JH, Jackson J, Milligan G, et al. A real-world analysis of migraine: a cross-sectional study of disease burden and treatment patterns. Headache. 2017;57:1532–1544.
    1. Wulf H, Maier C. Complications and side effects of stellate ganglion blockade. Results of a questionnaire survey. Anaesthesist. 1992;41:146–151.

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