Dynamics of anti-SARS-Cov-2 IgM and IgG antibodies among COVID-19 patients

Yu-Lin Lee, Chia-Hung Liao, Po-Yu Liu, Chien-Yu Cheng, Ming-Yi Chung, Chun-Eng Liu, Sui-Yuan Chang, Po-Ren Hsueh, Yu-Lin Lee, Chia-Hung Liao, Po-Yu Liu, Chien-Yu Cheng, Ming-Yi Chung, Chun-Eng Liu, Sui-Yuan Chang, Po-Ren Hsueh

No abstract available

Keywords: Anti-SARS-CoV-2 IgM/IgG, rRT-PCR; Antibody response; COVID-19; Disease course.

Conflict of interest statement

Declaration of Competing Interest The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Dynamics of anti-SARS-CoV-2 IgG and IgM, and results of real‐time reverse transcriptase‐PCR (rRT-PCR) for 14 COVID-19 patients. (A) Six patients in the symptomatic group. (B) Eight patients in the asymptomatic/mild symptom group. The number in the columns indicates days after onset of symptoms or the time when COVID-19 was confirmed among asymptomatic patients. Arrows indicate patients who were still hospitalized and did not achieve negative conversion of rRT-PCR results at the end of the study.

References

    1. Liu W.D., Chang S.Y., Wang J.T., Tsai M.J., Hung C.C., Hsu C.L. Prolonged virus shedding even after seroconversion in a patient with COVID-19. J Infect. 2020 Apr 10 doi: 10.1016/j.jinf.2020.03.063.
    1. Lee N.Y., Li C.W., Tsai H.P., Chen P.L., Syue L.S., Li M.C., Tsai C.S., Lo C.L., Hsueh P.R., Ko W.C. A case of COVID-19 and pneumonia returning from Macau in Taiwan: Clinical course and anti-SARS-CoV-2 IgG dynamic. J Microbiol Immunol Infect. 2020 doi: 10.1016/j.jmii.2020.03.003.
    1. Package Insert. ALLTEST 2019-nCoV IgG/IgM Rapid Test Cassette, Hangzhou ALLTEST Biotech Co., Ltd. Hangzhou, China. .
    1. Li Z., Yi Y., Luo X., Xiong N., Liu Y., Li S. Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis. J Med Virol. 2020 doi: 10.1002/jmv.25727.
    1. Hsih W.H., Cheng M.Y., Ho M.W., Chou C.H., Lin P.C., Chi C.Y. Featuring COVID-19 cases via screening symptomatic patients with epidemiologic link during flu season in a medical center of central Taiwan. J Microbiol Immunol Infect. 2020 doi: 10.1016/j.jmii.2020.03.008.
    1. Nie Y., Wang G., Shi X., Zhang H., Qiu Y., He Z. Neutralizing antibodies in patients with severe acute respiratory syndrome-associated coronavirus infection. J Infect Dis. 2020;190:1119–1126. http://doi: 10.086/423286.
    1. Chen L., Xiong J., Bao L., Shi Y. Convalescent plasma as a potential therapy for COVID-19. Lancet Infect Dis. 2020;27:30141–30149. doi: 10.1016/S1473-3099(20)30141-9.
    1. Wang J.T., Lin Y.Y., Chang S.Y., Yeh S.H., Hu B.H., Chen P.J. The role of phylogenetic analysis in clarifying the infection source of a COVID-19 patient. J Infect. 2020 Apr 8 doi: 10.1016/j.jinf.2020.03.031. S0163-4453(20)30159-6.

Source: PubMed

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