Epidemiology of knee osteoarthritis in India and related factors

Chandra Prakash Pal, Pulkesh Singh, Sanjay Chaturvedi, Kaushal Kumar Pruthi, Ashok Vij, Chandra Prakash Pal, Pulkesh Singh, Sanjay Chaturvedi, Kaushal Kumar Pruthi, Ashok Vij

Abstract

Background: Among the chronic rheumatic diseases, hip and knee osteoarthritis (OA) is the most prevalent and is a leading cause of pain and disability in most countries worldwide. Its prevalence increases with age and generally affects women more frequently than men. OA is strongly associated with aging and heavy physical occupational activity, a required livelihood for many people living in rural communities in developing countries. Determining region-specific OA prevalence and risk factor profiles will provide important information for planning future cost effective preventive strategies and health care services.

Materials and methods: The study was a community based cross sectional study to find out the prevalence of primary knee OA in India which has a population of 1.252 billion. The study was done across five sites in India. Each site was further divided into big city, small city, town, and village. The total sample size was 5000 subjects. Tools consisted of a structured questionnaire and plain skiagrams for confirmation of OA. Diagnosis was done using Kellgren and Lawrence scale for osteoarthritis.

Results: Overall prevalence of knee OA was found to be 28.7%. The associated factors were found to be female gender (prevalence of 31.6%) (P = 0.007), obesity (P = 0.04), age (P = 0.001) and sedentary work (P = 0.001).

Conclusions: There is scarcity of studies done in India which has varied socio geographical background and communities. We conducted this study for analyzing the current prevalence of OA in different locations. This study has evidenced a large percentage of population as borderline OA; therefore, it depends mainly on the prevention of modifiable risk factors to preserve at ease movement in elderly population through awareness programs.

Keywords: Knee osteoarthritis; Osteoarthritis; epidemiology; knee; knee joint; prevalence; related factors; risk factors.

References

    1. Silman AJ, Hochberg MC. 2nd ed. Oxford: Oxford University Press; 2001. Epidemiology of the Rheumatic Diseases.
    1. Akinpelu AO, Alonge TO, Adekanla BA, Odole AC. Prevalence and pattern of symptomatic knee osteoarthritis in Nigeria: A community-based study. Internet J Allied Health Sci Pract. 2009;7:3.
    1. Symmons D, Mathers C, Pfleger B. Global Burden of Osteoarthritis in year 2000: Global burden of disease 2000 study. World health report. 2002;5 Version 2.
    1. Solomon L, Beighton P, Lawrence JS. Rheumatic disorders in the South African Negro. Patrt II. Osteo-arthrosis. S Afr Med J. 1975;49:1737–40.
    1. Davis MA, Ettinger WH, Neuhaus JM, Hauck WW. Sex differences in osteoarthritis of the knee. The role of obesity. Am J Epidemiol. 1988;127:1019–30.
    1. Carmona L, Ballina J, Gabriel R, Laffon A EPISER Study Group. The burden of musculoskeletal diseases in the general population of Spain: Results from a national survey. Ann Rheum Dis. 2001;60:1040–5.
    1. Felson DT. Epidemiology of hip and knee osteoarthritis. Epidemiol Rev. 1988;10:1–28.
    1. Haq SA, Davatchi F, Dahaghin S, Islam N, Ghose A, Darmawan J, et al. Development of a questionnaire for identification of the risk factors for osteoarthritis of the knees in developing countries. A pilot study in Iran and Bangladesh. An ILAR-COPCORD phase III study. Int J Rheum Dis. 2010;13:203–14.
    1. Zeng QY, Chen R, Xiao ZY, Huang SB, Liu Y, Xu JC, et al. Low prevalence of knee and back pain in southeast China; the Shantou COPCORD study. J Rheumatol. 2004;31:2439–43.
    1. Zhang Y, Xu L, Nevitt MC, Aliabadi P, Yu W, Qin M, et al. Comparison of the prevalence of knee osteoarthritis between the elderly Chinese population in Beijing and whites in the United States: The Beijing osteoarthritis study. Arthritis Rheum. 2001;44:2065–71.
    1. Kang X, Fransen M, Zhang Y, Li H, Ke Y, Lu M, et al. The high prevalence of knee osteoarthritis in a rural Chinese population: The Wuchuan osteoarthritis study. Arthritis Rheum. 2009;61:641–7.
    1. Hoy DG, Fransen M, March L, Brooks P, Durham J, Toole MJ. In rural Tibet, the prevalence of lower limb pain, especially knee pain, is high: An observational study. J Physiother. 2010;56:49–54.
    1. Muraki S, Oka H, Akune T, Mabuchi A, En-Yo Y, Yoshida M, et al. Prevalence of radiographic knee osteoarthritis and its association with knee pain in the elderly of Japanese population-based cohorts: The ROAD study. Osteoarthritis Cartilage. 2009;17:1137–43.
    1. Salve H, Gupta V, Palanivel C, Yadav K, Singh B. Prevalence of knee osteoarthritis amongst perimenopausal women in an urban resettlement colony in South Delhi. Indian J Public Health. 2010;54:155–7.
    1. Sharma MK, Swami HM, Bhatia V. An epidemiological study of correlates of osteoarthritis in geriatric population of UT Chandigarh. Indian J Community Med. 2007;32:1–3.
    1. Martin KR, Kuh D, Harris TB, Guralnik JM, Coggon D, Wills AK. Body mass index, occupational activity, and leisure-time physical activity: An exploration of risk factors and modifiers for knee osteoarthritis in the 1946 British birth cohort. BMC Musculoskelet Disord. 2013;14:219.
    1. Blagojevic M, Jinks C, Jeffery A, Jordan KP. Risk factors for onset of osteoarthritis of the knee in older adults: A systematic review and meta-analysis. Osteoarthritis Cartilage. 2010;18:24–33.
    1. D’Souza JC, Werner RA, Keyserling WM, Gillespie B, Rabourn R, Ulin S, et al. Analysis of the Third National Health and Nutrition Examination Survey (NHANES III) using expert ratings of job categories. Am J Ind Med. 2008;51:37–46.
    1. Dawson J, Juszczak E, Thorogood M, Marks SA, Dodd C, Fitzpatrick R. An investigation of risk factors for symptomatic osteoarthritis of the knee in women using a life course approach. J Epidemiol Community Health. 2003;57:823–30.
    1. Manninen P, Heliövaara M, Riihimäki H, Suoma-Iainen O. Physical workload and the risk of severe knee osteoarthritis. Scand J Work Environ Health. 2002;28:25–32.
    1. Coggon D, Croft P, Kellingray S, Barrett D, McLaren M, Cooper C. Occupational physical activities and osteoarthritis of the knee. Arthritis Rheum. 2000;43:1443–9.
    1. Yoshimura N, Nishioka S, Kinoshita H, Hori N, Nishioka T, Ryujin M, et al. Risk factors for knee osteoarthritis in Japanese women: Heavy weight, previous joint injuries, and occupational activities. J Rheumatol. 2004;31:157–62.
    1. Sandmark H, Vingård E. Sports and risk for severe osteoarthrosis of the knee. Scand J Med Sci Sports. 1999;9:279–84.
    1. Cooper C, McAlindon T, Coggon D, Egger P, Dieppe P. Occupational activity and osteoarthritis of the knee. Ann Rheum Dis. 1994;53:90–3.
    1. Klussmann A, Gebhardt H, Nübling M, Liebers F, Quirós Perea E, Cordier W, et al. Individual and occupational risk factors for knee osteoarthritis: Results of a case-control study in Germany. Arthritis Res Ther. 2010;12:R88.
    1. Lau EC, Cooper C, Lam D, Chan VN, Tsang KK, Sham A. Factors associated with osteoarthritis of the hip and knee in Hong Kong Chinese: Obesity, joint injury, and occupational activities. Am J Epidemiol. 2000;152:855–62.
    1. Riyazi N, Meulenbelt I, Kroon HM, Ronday KH, Hellio Le Graverand MP, Rosendaal FR, et al. Evidence for familial aggregation of hand, hip, and spine osteoarthritis (OA), but not knee OA in siblings with OA at multiple sites. The GARP study. Ann Rheum Dis. 2005;64:438–43.

Source: PubMed

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