Correlates and predictors of patient satisfaction with drug therapy and combined drug therapy and behavioral training for urgency urinary incontinence in women
Patricia S Goode, Kathryn L Burgio, Stephen R Kraus, Kimberly Kenton, Heather J Litman, Holly E Richter, Urinary Incontinence Treatment Network, William Steers, Ananias Diokno, Veronica Mallett, Salil Khandwala, Linda Brubaker, MaryPat FitzGerald, Holly E Richter, L Keith Lloyd, Michael Albo, Charles Nager, Toby C Chai, Harry W Johnson, Halina M Zyczynski, Wendy Leng, Philippe Zimmern, Gary Lemack, Stephen Kraus, Thomas Rozanski, Peggy Norton, Lindsey Kerr, Sharon Tennstedt, Anne Stoddard, Debuene Chang, John W Kusek, Leroy M Nyberg, Anne M Weber, Diane Borello-France, Kathryn L Burgio, Seine Chiang, Ash Dabbous, Chiara Ghetti, Patricia S Goode, Lee N Hammontree, Kimberly Kenton, Jerry Lowder, Karl Luber, Emily Lukacz, Alayne Markland, Shawn Menefee, Pamela Moalli, Kenneth Peters, Joseph Schaffer, Amanda Simsiman, Larry Sirls, Robert Starr, R Edward Varner, Rosemary Bradt, Laura Burr, Karen Debes, Tamara Dickinson, Rosanna Dinh, Judy Gruss, Alice Howell, Kathy Jesse, D Lynn Kalinoski, Kristen Mangus, Karen Mislanovich, Judy Murray, Shelly O'Meara, Janese Parent, Norma Pope, Caren Prather, Sylvia Sluder, Mary Tulke, Robin Willingham, Gisselle Zazueta-Damian, Dorothy Atkins, Jan Baker, Karen Debes, Kathy Jesse, Ryanne R Johnson, Kathryn Koches, R Jeannine McCormick, Karen Mislanovich, Christy Moore, Elva Kelly Moore, Amy Mutch, Betsy Nielsen-Omeis, Lisa Radebaugh, Patsy Riley, Karen VandeVegt, Kimberly J Dandreo, Corinne J Leifer, Heather Litman, Susan M McDermott, Anne Stoddard, Sharon Tennstedt, Liane Tinsley, Elizabeth A Gormley, Paul Abrams, Diedre Bland, J Quentin Clemens, John Connett, William Henderson, Dee Fenner, Sheryl Kelsey, Deborah Myers, Jacek Mostwin, Bassem Wadie, Patricia S Goode, Kathryn L Burgio, Stephen R Kraus, Kimberly Kenton, Heather J Litman, Holly E Richter, Urinary Incontinence Treatment Network, William Steers, Ananias Diokno, Veronica Mallett, Salil Khandwala, Linda Brubaker, MaryPat FitzGerald, Holly E Richter, L Keith Lloyd, Michael Albo, Charles Nager, Toby C Chai, Harry W Johnson, Halina M Zyczynski, Wendy Leng, Philippe Zimmern, Gary Lemack, Stephen Kraus, Thomas Rozanski, Peggy Norton, Lindsey Kerr, Sharon Tennstedt, Anne Stoddard, Debuene Chang, John W Kusek, Leroy M Nyberg, Anne M Weber, Diane Borello-France, Kathryn L Burgio, Seine Chiang, Ash Dabbous, Chiara Ghetti, Patricia S Goode, Lee N Hammontree, Kimberly Kenton, Jerry Lowder, Karl Luber, Emily Lukacz, Alayne Markland, Shawn Menefee, Pamela Moalli, Kenneth Peters, Joseph Schaffer, Amanda Simsiman, Larry Sirls, Robert Starr, R Edward Varner, Rosemary Bradt, Laura Burr, Karen Debes, Tamara Dickinson, Rosanna Dinh, Judy Gruss, Alice Howell, Kathy Jesse, D Lynn Kalinoski, Kristen Mangus, Karen Mislanovich, Judy Murray, Shelly O'Meara, Janese Parent, Norma Pope, Caren Prather, Sylvia Sluder, Mary Tulke, Robin Willingham, Gisselle Zazueta-Damian, Dorothy Atkins, Jan Baker, Karen Debes, Kathy Jesse, Ryanne R Johnson, Kathryn Koches, R Jeannine McCormick, Karen Mislanovich, Christy Moore, Elva Kelly Moore, Amy Mutch, Betsy Nielsen-Omeis, Lisa Radebaugh, Patsy Riley, Karen VandeVegt, Kimberly J Dandreo, Corinne J Leifer, Heather Litman, Susan M McDermott, Anne Stoddard, Sharon Tennstedt, Liane Tinsley, Elizabeth A Gormley, Paul Abrams, Diedre Bland, J Quentin Clemens, John Connett, William Henderson, Dee Fenner, Sheryl Kelsey, Deborah Myers, Jacek Mostwin, Bassem Wadie
Abstract
Introduction and hypothesis: The goal was to identify correlates of patient satisfaction with drug and behavioral treatments for urge-predominant incontinence, which may help tailor treatments to improve satisfaction.
Methods: Planned secondary analysis of a multi-center, clinical trial randomizing 307 women to 10 weeks of tolterodine alone or combined with behavioral training. Satisfaction was measured using the Patient Satisfaction Question (PSQ). Potential correlates included baseline demographics, incontinence characteristics and prior treatments, history and physical parameters, expectations of treatment success, and outcome variables including the Global Perception of Improvement (GPI) and Urogenital Distress Inventory (UDI).
Results: After multivariable analysis, every 10-point increase in UDI change score increased odds of satisfaction by 11% (OR 1.11; 1.04-1.19). Odds of satisfaction increased among women reporting "much better" on the GPI (OR 13.8; 4.94-38.60).
Conclusions: Treatment satisfaction for women with urge-predominant incontinence was associated with patient-related outcomes reflecting impression of improvement and bother from incontinence-related symptoms.
Trial registration: ClinicalTrials.gov NCT00090584.
Source: PubMed