Clinical performance of Roche Cobas 4800 HPV Test
Miao Cui, Nicholas Chan, Momo Liu, Khanh Thai, Joanna Malaczynska, Ila Singh, David Zhang, Fei Ye, Miao Cui, Nicholas Chan, Momo Liu, Khanh Thai, Joanna Malaczynska, Ila Singh, David Zhang, Fei Ye
Abstract
Evaluation of the Cobas 4800 test demonstrated that Cobas had a low rate of cross-reactivity with low-risk human papillomavirus (lrHPV), a 3.74% disconcordance rate between prealiquots and postaliquots, and failure rates of 4.57% and 1.16%, respectively, after vortexing and swirling. This study demonstrated that the Cobas test has good sensitivity, accuracy, and reproducibility for detecting 14 high-risk HPV (hrHPV) genotypes.
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Source: PubMed