Intravenous lidocaine for the treatment of acute pain in the emergency department

Brendan Michael Fitzpatrick, Michael Eugene Mullins, Brendan Michael Fitzpatrick, Michael Eugene Mullins

Abstract

Objective: To evaluate intravenous lidocaine's safety and efficacy as an analgesic agent in the treatment of a variety of painful conditions presenting to the emergency department.

Methods: This case series identified seventeen patients who received lidocaine over a six month period and recorded demographic data, amount of lidocaine administered, the amount of opioid medication administered before and after lidocaine, pre- and post-lidocaine pain scores, and any qualitative descriptors of the patient's pain recorded in the record. Side effects and adverse events were also recorded.

Results: Of the seven patients who had a pre- and post-lidocaine pain score recorded, the mean reduction was 3 points on a 10 point scale. Patients who received lidocaine used less opioid medication. One patient received an improperly high dose of lidocaine and suffered a brief seizure and cardiac arrest, but was quickly resuscitated.

Conclusion: This series suggests that lidocaine may be a useful adjunct in the treatment of acutely painful conditions in the emergency department.

Keywords: Analgesia; Lidocaine; Pain control.

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

References

    1. Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular CarePart 6: advanced cardiovascular life support: section 5: pharmacology I: agents for arrhythmias. The American Heart Association in collaboration with the International Liaison Committee on Resuscitation. Circulation. 2000;102(8 Suppl):I112–28.
    1. Salhi B, Stettner E. In defense of the use of lidocaine in rapid sequence intubation. Ann Emerg Med. 2007;49:84–6.
    1. Sharma S, Rajagopal MR, Palat G, Singh C, Haji AG, Jain D. A phase II pilot study to evaluate use of intravenous lidocaine for opioid-refractory pain in cancer patients. J Pain Symptom Manage. 2009;37:85–93.
    1. De Oliveira GS, Jr, Fitzgerald P, Streicher LF, Marcus RJ, McCarthy RJ. Systemic lidocaine to improve postoperative quality of recovery after ambulatory laparoscopic surgery. Anesth Analg. 2012;115:262–7.
    1. Thomas J, Kronenberg R, Cox MC, Naco GC, Wallace M, von Gunten CF. Intravenous lidocaine relieves severe pain: results of an inpatient hospice chart review. J Palliat Med. 2004;7:660–7.
    1. Soleimanpour H, Hassanzadeh K, Mohammadi DA, Vaezi H, Esfanjani RM. Parenteral lidocaine for treatment of intractable renal colic: a case series. J Med Case Rep. 2011;5:256.
    1. Soleimanpour H, Hassanzadeh K, Vaezi H, Golzari SE, Esfanjani RM, Soleimanpour M. Effectiveness of intravenous lidocaine versus intravenous morphine for patients with renal colic in the emergency department. BMC Urol. 2012;12:13.
    1. Vahidi E, Shakoor D, Aghaie Meybodi M, Saeedi M. Comparison of intravenous lidocaine versus morphine in alleviating pain in patients with critical limb ischaemia. Emerg Med J. 2015;32:516–9.
    1. Roden DM. Antiarrhythmic drugs. In: Limbird LE, Gilman AG, editors. Goodman & Gilman’s the pharmacological basis of therapeutics. 10th ed. New York: McGraw-Hill; 2001. pp. 961–2.
    1. McCleane G. Intravenous lidocaine: an outdated or underutilized treatment for pain? J Palliat Med. 2007;10:798–805.
    1. Devor M, Wall PD, Catalan N. Systemic lidocaine silences ectopic neuroma and DRG discharge without blocking nerve conduction. Pain. 1992;48:261–8.
    1. Rosen N, Marmura M, Abbas M, Silberstein S. Intravenous lidocaine in the treatment of refractory headache: a retrospective case series. Headache. 2009;49:286–91.
    1. Wasiak J, Spinks A, Costello V, et al. Adjuvant use of intravenous lidocaine for procedural burn pain relief: a randomized double-blind, placebo-controlled, cross-over trial. Burns. 2011;37:951–7.
    1. Tanen DA, Shimada M, Danish DC, Dos Santos F, Makela M, Riffenburgh RH. Intravenous lidocaine for the emergency department treatment of acute radicular low back pain, a randomized controlled trial. J Emerg Med. 2014;47:119–24.

Source: PubMed

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