Assessment of glomerular filtration rate measurement with plasma sampling: a technical review
Anthony W Murray, Mark C Barnfield, Michael L Waller, Tania Telford, A Michael Peters, Anthony W Murray, Mark C Barnfield, Michael L Waller, Tania Telford, A Michael Peters
Abstract
This article reviews available radionuclide-based techniques for glomerular filtration rate (GFR) measurement, focusing on clinical indications for GFR measurement, ideal GFR radiopharmaceutical tracer properties, and the 2 most common tracers in clinical use. Methods for full, 1-compartment, and single-sample renal clearance characterization are discussed. GFR normalization and the role of GFR measurement in chemotherapy dosing are also considered.
Keywords: GFR measurement; GFR normalization; glomerular filtration rate; radiopharmaceutical tracer; technical review.
Source: PubMed