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Mother and Infant Study Cohort (MISC)-

22 giugno 2018 aggiornato da: Hadia Radwan, University of Sharjah

Impact of Feeding Patterns on Adiposity and Cardiometabolic Markers in Baby and Mother: A Prospective Cohort Study

This study aims to explore breastfeeding and complementary feeding practices of mothers in the United Arab Emirates (UAE) and its relation to the early life determinants of obesity and non-communicable diseases (NCDs). This research study will follow a prospective cohort approach. Two hundred and fifty mother-infant pairs will be followed for 18 months.

The hypothesis of this research study is that exclusive breastfeeding of the infant will provide potential protective effect against cardiometabolic risk factors. This study will also hypothesize that mothers who exclusively breastfeed their newborns would experience greater postpartum weight and body fat loss than mothers who are not breastfeeding.

Panoramica dello studio

Stato

Completato

Condizioni

Adiposity, Breast Feeding

Descrizione dettagliata

United Arab Emirates(UAE) is facing two critical situations: high incidence of obesity and chronic diseases and suboptimal infant feeding practices as reported by the Ministry of Health in the UAE. So early identification of preventive markers of cardiometabolic risk factors in breast milk is important for developing early intervention strategies to optimize health care for individuals and communities especially in countries suffering from high rates of obesity and chronic diseases such as the UAE.

The purpose of this study is to prospectively follow up with the mothers and their infants (from 0-18months of infants age). It will explore breastfeeding and complementary feeding practices of mothers in UAE and its relation to the early life determinants of obesity and non-communicable diseases (NCDs). It will examine the components of human milk which might offer a protective benefit against obesity and its health consequences in infancy. It will also evaluate the feeding practices of the mothers and her nutritional status and relates it to their infants' growth and development.

It is expected that this research study will fill an important knowledge gap in the understanding of the feeding practices of mothers and its relation to early-life determinants of obesity and other chronic diseases in the UAE.

Tipo di studio

Osservativo

Iscrizione (Effettivo)

257

Contatti e Sedi

Questa sezione fornisce i recapiti di coloro che conducono lo studio e informazioni su dove viene condotto lo studio.

Luoghi di studio

Emirati Arabi Uniti
- Shajah
  - Sharjah, Shajah, Emirati Arabi Uniti, 27272
    - Hadia Radwan

Criteri di partecipazione

I ricercatori cercano persone che corrispondano a una certa descrizione, chiamata criteri di ammissibilità. Alcuni esempi di questi criteri sono le condizioni generali di salute di una persona o trattamenti precedenti.

Criteri di ammissibilità

Età idonea allo studio

Da 19 anni a 40 anni (Adulto)

Accetta volontari sani

Sì

Sessi ammissibili allo studio

Femmina

Metodo di campionamento

Campione non probabilistico

Popolazione di studio

The sample population is Emirati and Arab expatriate mothers, aged 19 to 40 years old; visiting Mother and Child Centers (MCH) and Primary Healthcare Centers (PHC) in Dubai and Sharjah.

The selected mothers (who will be recruited during their 3rd trimester) were invited to participate in the study after being consented for their procedures and they will sign on the behalf of their babies

Descrizione

Inclusion Criteria:

Pregnant women:
- Emirate nationality or Arab expatriate
- Age: 19-40 years
- Singleton pregnancy
- Within the third trimester of pregnancy (27-42 weeks of gestation)
- Free of chronic diseases (diabetes, hypertension, kidney disease, cancer, or other chronic diseases), autoimmune disorders, or infections with the human immunodeficiency virus, or hepatitis in preconception

Exclusion Criteria:

Multiple pregnancies (pregnant with two or more fetuses)
High-risk pregnancy or pre-eclampsia
History of chronic diseases
Preterm (<37 weeks of gestation) or late-term (>42 weeks of gestation) infants
Congenital diseases or any health condition that could deter breastfeeding

Piano di studio

Questa sezione fornisce i dettagli del piano di studio, compreso il modo in cui lo studio è progettato e ciò che lo studio sta misurando.

Come è strutturato lo studio?

Dettagli di progettazione

Cosa sta misurando lo studio?

Misure di risultato primarie

Misura del risultato	Misura Descrizione	Lasso di tempo
relationship between exclusive breastfeeding and maternal serum levels of adiponectin Lasso di tempo: 18 months	measuring the adiponectin level in the maternal serum at 6 months postpartum	18 months
relationships between maternal milk levels of adiponectin with infants serum levels of adiponectin Lasso di tempo: 18 months	measuring the adiponectin level and in the infants serum and in the breast milk	18 months
Comparison of the infant adiponectin serum level in exclusive breastfeeding mothers versus mothers who do not exclusively breastfeed their infants Lasso di tempo: 18 months	measuring the adiponectin serum level in the infants of exclusive breastfeeding group and other breastfeeding patterns	18 months
Association between duration of breastfeeding and mothers' anthropometric measurements(weight in kilograms and Height in meters ) Lasso di tempo: 18 months	Measuring the weight in kilograms and height in meters weight and height will be combined to report BMI in kg/m^2 of the mothers at different timelines in relation to breastfeeding duration	18 months
Assessment of the anthropometric measurements (weight in kilograms and height in meters) of the mothers according to the breastfeeding patterns Lasso di tempo: 18 months	Measuring the weight in kilograms and height in meters weight and height will be combined to report BMI in kg/m^2 of mothers at different timelines in relation to different breastfeeding patterns	18 months
relationship between exclusive breastfeeding and breast milk levels of adiponectin Lasso di tempo: 18 months	measuring the adiponectin level in the breast milk at 6 months postpartum	18 months
Assessment of the anthropometric measurements of the infant according to the breastfeeding patterns Lasso di tempo: 18 months	measuring the weight, height, mid upper arm circumference of the infant at different timelines in relation to the breastfeeding patterns	18 months

Collaboratori e investigatori

Qui è dove troverai le persone e le organizzazioni coinvolte in questo studio.

Sponsor

University of Sharjah

Collaboratori

Al Jalila Foundation

Investigatori

Investigatore principale: Hadia Radwan, PhD, University of Sharjah

Studiare le date dei record

Queste date tengono traccia dell'avanzamento della registrazione dello studio e dell'invio dei risultati di sintesi a ClinicalTrials.gov. I record degli studi e i risultati riportati vengono esaminati dalla National Library of Medicine (NLM) per assicurarsi che soddisfino specifici standard di controllo della qualità prima di essere pubblicati sul sito Web pubblico.

Studia le date principali

Inizio studio (Effettivo)

1 dicembre 2015

Completamento primario (Effettivo)

20 dicembre 2017

Completamento dello studio (Effettivo)

20 febbraio 2018

Date di iscrizione allo studio

Primo inviato

2 maggio 2018

Primo inviato che soddisfa i criteri di controllo qualità

22 giugno 2018

Primo Inserito (Effettivo)

5 luglio 2018

Aggiornamenti dei record di studio

Ultimo aggiornamento pubblicato (Effettivo)