Concentric vs Eccentric Exercise in Blood Flow Restriction Training
2026年7月14日 更新者：METEHAN YANA、Karabuk University
Comparison of the Effectiveness of Concentric and Eccentric Exercises in Blood Flow Restriction Training
This randomized controlled trial will investigate the effects of blood flow restriction (BFR) training combined with concentric or eccentric exercise on upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy adults aged 18-35 years. A total of 34 participants will be randomly allocated to either a BFR combined with concentric exercise group (n=17) or a BFR combined with eccentric exercise group (n=17).
Before the intervention, maximal muscle strength will be determined using a one-repetition maximum (1RM) test for the dominant elbow flexor muscles. Upper extremity reaction speed will be assessed using the Nelson Hand Reaction Test. Biceps brachii muscle strength will be measured with a digital dynamometer, and muscle oxygenation will be evaluated using a near-infrared spectroscopy (NIRS) device. All outcome measures will be obtained 72 hours before the intervention and repeated 72 hours after completion of the training program by the same investigator.
The findings of this study will contribute to understanding whether concentric or eccentric exercise combined with BFR training provides greater improvements in upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy individuals.
調査の概要
状態
状態
招待による登録
条件
条件
介入・治療
介入・治療
研究の種類
研究の種類
介入
入学 (推定)
入学
34
段階
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究場所
-
-
Karabük Province
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Karabük、Karabük Province、トルコ（Türkiye）、78050
- Karabuk University
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-
参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
適格基準
就学可能な年齢
- 大人
健康ボランティアの受け入れ
はい
説明
Inclusion Criteria:
- Being between 18 and 35 years of age
- Physically inactive or minimally active individuals (International Physical Activity Questionnaire-Short Form. IPAQ-CF, <3000 MET-min/week)
Exclusion Criteria:
- Having a history of musculoskeletal surgery within the last 6 months
- Individuals with a history of orthopedic surgery within the last 6 months
- Having high systolic blood pressure (≥140 mmHg)
- Having a current history of cardiovascular disease
- Participants who did not volunteer to participate in the study and did not provide informed consent were excluded from the study.
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：他の
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：なし（オープンラベル）
アーム数
2
武器と介入
参加者グループ / アーム参加者グループ / アーム |
介入・治療介入・治療 |
|---|---|
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アクティブコンパレータ：CONCENTRIC GROUP
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Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
|
|
アクティブコンパレータ：ECCENTRIC GROUP
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Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
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この研究は何を測定していますか？
主要な結果の測定
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Upper Extremity Reaction Time
時間枠：Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Upper extremity reaction time will be assessed using the Nelson Hand Reaction Test.
Participants will complete five trials, the highest and lowest values will be discarded, and the mean of the remaining three trials will be used for analysis.
Reaction time will be calculated from the ruler drop distance using the standard equation.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Biceps Brachii Muscle Strength
時間枠：Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Biceps brachii muscle strength will be measured using an ActivForce 2 digital dynamometer.
Three maximal isometric contractions will be performed with 30-second rest intervals, and the highest value will be used for analysis.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Hand Grip Strength
時間枠：Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Hand grip strength will be measured using a hydraulic hand dynamometer.
Participants will perform three maximal contractions with 30-second rest intervals, and the highest value will be recorded for analysis.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Pinch Strength
時間枠：Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
Pinch strength will be assessed using a pinch dynamometer.
Three maximal trials will be performed with 30-second rest intervals, and the highest value will be used for analysis.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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One-Repetition Maximum
時間枠：Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Maximum muscle strength of the elbow flexors will be estimated using the Epley equation based on the maximum number of repetitions completed with a fixed load (2 kg for females and 5 kg for males).
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Muscle Oxygen Saturation
時間枠：Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
Muscle oxygen saturation (SmO₂) of the biceps brachii will be measured using a MOXY near-infrared spectroscopy (NIRS) device.
Baseline SmO₂ will be recorded before the 1RM test, continuous SmO₂ values will be monitored throughout the test, and recovery values will be recorded for 2-3 minutes after the test.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
出版物と役立つリンク
研究に関する情報を入力する責任者は、自発的にこれらの出版物を提供します。これらは、研究に関連するあらゆるものに関するものである可能性があります。
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (推定)
研究開始
2026年8月1日
一次修了 (推定)
一次修了
2026年10月1日
研究の完了 (推定)
研究の完了
2026年11月1日
試験登録日
最初に提出
最初に提出
2026年7月14日
QC基準を満たした最初の提出物
QC基準を満たした最初の提出物
2026年7月14日
最初の投稿 (実際)
最初の投稿
2026年7月17日
学習記録の更新
投稿された最後の更新 (実際)
投稿された最後の更新
2026年7月17日
QC基準を満たした最後の更新が送信されました
QC基準を満たした最後の更新が送信されました
2026年7月14日
最終確認日
最終確認日
2026年7月1日
詳しくは
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。