Effect of Hydrogen-rich Water During Tapering on Recovery After Functional Overreaching in Basketball Players
2026년 7월 27일 업데이트: Jakub Krejci, Palacky University
Effect of Hydrogen-rich Water Supplementation During Tapering on Recovery After Functional Overreaching in Competitive Male Basketball Players: A Randomized, Double-blind, Placebo-controlled Paralel-group Trial
The goal of this clinical trial is to evaluate whether hydrogen-rich water supplementation during tapering improves recovery after functional overreaching in competitive male basketball players aged 18-35 years. The main questions it aims to answer are:
- Does hydrogen-rich water improve autonomic recovery after functional overreaching?
- Does hydrogen-rich water improve recovery in biochemical, performance, and subjective feeling outcomes during tapering?
Researchers will compare hydrogen-rich water to placebo (water containing no molecular hydrogen) to determine whether molecular hydrogen improves recovery after accumulated fatigue has been induced by functional overreaching. Participants will:
- Complete a training cycle including normal training, functional overreaching, and tapering.
- Consume hydrogen-rich or placebo water daily during the one-week tapering period.
- Undergo repeated testing of autonomic nervous system, blood biochemical markers, performance, and subjective soreness.
연구 개요
상태
상태
모병
정황
정황
개입 / 치료
개입 / 치료
상세 설명
The study consists of an initial screening and entry testing phase, followed by one week of normal training, two weeks of functional overreaching, and one week of tapering. During the functional overreaching period, training load is increased to approximately 120-130% of normal training load to induce accumulated fatigue. During the tapering period, training volume is reduced to approximately 50-60% of normal training volume to support recovery and performance rebound.
The molecular hydrogen is administered only during the tapering period. Participants in the experimental group consume 2.5 L per day of hydrogen-rich water. The total daily dose is divided into 0.5 L in the morning, 1.5 L around training, and 0.5 L in the evening. Participants in the placebo group consume visually matched placebo water according to the same total daily intake and timing schedule. Supplementation adherence is monitored using logs, dose counts, and attendance records. Participants are randomly assigned in a 1:1 ratio to either the experimental group or the placebo group. Randomization is performed using a block scheme and a computer random number generator.
Testing is performed at multiple time points: entry laboratory testing, baseline after normal training, post-functional overreaching, and post-taper. The primary interval for evaluation is the change from post-functional overreaching to post-taper. Statistical analysis is based on a t-test or analysis of variance. Data that not follow a normal distribution are treated using a logarithmic transformation or analyzed using nonparametric tests. The significance level is set at 0.05.
연구 유형
연구 유형
중재적
등록 (추정된)
등록
30
단계
단계
- 해당 없음
연락처 및 위치
이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.
연구 연락처
연구 연락처
- 이름: Jakub Krejci, PhD
- 이메일: jakub.krejci@upol.cz
연구 연락처 백업
- 이름: Jan Kvas
- 전화번호: +420774678756
- 이메일: jan.kvas01@upol.cz
연구 장소
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Olomouc, 체코, 77111
- 모병
- Palacky University, Faculty of Physical Culture
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연락하다:
- Jan Kvas
- 전화번호: +420774678756
- 이메일: jan.kvas01@upol.cz
-
-
참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
자격 기준
공부할 수 있는 나이
- 성인
건강한 자원 봉사자를 받아들입니다
예
설명
Inclusion Criteria:
- Competitive male basketball players.
- Signed informed consent.
- Completion of entry medical and laboratory screening.
Exclusion Criteria:
- Acute injury or infection.
- History or presence of relevant cardiovascular, respiratory, metabolic, or other disease that may affect the study results.
- Use of medication affecting recovery markers or study results.
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 기초 과학
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 더블
팔의 수
2
무기와 개입
참가자 그룹 / 팔참가자 그룹 / 팔 |
개입 / 치료개입 / 치료 |
|---|---|
|
실험적: Hydrogen-rich water
Hydrogen-rich water administered at a dose of 2.5 L per day during a one-week tapering period.
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Hydrogen-rich water with molecular hydrogen concentration >1.0 ppm.
다른 이름들:
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위약 비교기: Placebo water
Placebo water administered at a dose of 2.5 L per day during a one-week tapering period.
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Tap water without molecular hydrogen.
|
연구는 무엇을 측정합니까?
주요 결과 측정
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
RMSSD
기간: One-week change between post-overreaching and post-taper.
|
The root mean square of successive differences of RR intervals (RMSSD) is used as an index of parasympathetic activity and is calculated from an ECG using heart rate variability analysis.
|
One-week change between post-overreaching and post-taper.
|
2차 결과 측정
2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Creatine kinase
기간: One-week change between post-overreaching and post-taper.
|
Blood creatine kinase concentration is used as a marker of muscle damage.
|
One-week change between post-overreaching and post-taper.
|
|
High-sensitivity C-reactive protein
기간: One-week change between post-overreaching and post-taper.
|
High-sensitivity C-reactive protein concentration is used as a marker of systemic inflammatory.
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One-week change between post-overreaching and post-taper.
|
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Cortisol
기간: One-week change between post-overreaching and post-taper.
|
Blood cortisol concentration is used as a marker of physiological stress response.
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One-week change between post-overreaching and post-taper.
|
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Testosterone
기간: One-week change between post-overreaching and post-taper.
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Blood testosterone concentration is used as a marker related to anabolic-catabolic balance.
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One-week change between post-overreaching and post-taper.
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Urea
기간: One-week change between post-overreaching and post-taper.
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Blood urea concentration is used as a marker related to metabolic and protein-turnover stress.
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One-week change between post-overreaching and post-taper.
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Leukocytes
기간: One-week change between post-overreaching and post-taper.
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Blood leukocyte count is used as a marker of immune-related response to training.
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One-week change between post-overreaching and post-taper.
|
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Lymphocytes
기간: One-week change between post-overreaching and post-taper.
|
Blood lymphocyte count is used as a marker of immune-related response to training.
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One-week change between post-overreaching and post-taper.
|
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Neutrophils
기간: One-week change between post-overreaching and post-taper.
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Blood lymphocyte count is used as a marker of imflammatory response to training.
|
One-week change between post-overreaching and post-taper.
|
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Reactive strength index
기간: One-week change between post-overreaching and post-taper.
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Reactive strength index is used as an marker of neuromuscular function of the lower limbs and is measured using a drop jump.
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One-week change between post-overreaching and post-taper.
|
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Hangrip test
기간: One-week change between post-overreaching and post-taper.
|
Handgrip test is used as a marker of forearm muscle strength and is measured using a dynamometer.
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One-week change between post-overreaching and post-taper.
|
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20-m sprint
기간: One-week change between post-overreaching and post-taper.
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20-m sprint test is used to assess linear speed.
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One-week change between post-overreaching and post-taper.
|
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Repeated sprint
기간: One-week change between post-overreaching and post-taper.
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20 x 15 m repeated sprint test is used to asses repeated sprint ability.
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One-week change between post-overreaching and post-taper.
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Agility T-test
기간: One-week change between post-overreaching and post-taper.
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Agility T-test is used to assess planned change-of-direction performance.
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One-week change between post-overreaching and post-taper.
|
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Basketball jump shot accuracy test
기간: One-week change between post-overreaching and post-taper.
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Basketball jump shot accuracy test is used to assess basketball-specific performance.
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One-week change between post-overreaching and post-taper.
|
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Muscle soreness
기간: One-week change between post-overreaching and post-taper.
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Muscle soreness is assessed subjectively using a visual analog scale, which is represented by a 100 mm line marked 0 (no pain) and 100 (worst imaginable pain).
|
One-week change between post-overreaching and post-taper.
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공동 작업자 및 조사자
여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
수사관
수사관
- 수석 연구원: Jan Kvas, Palacky University
연구 기록 날짜
이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.
연구 주요 날짜
연구 시작 (실제)
연구 시작
2026년 7월 27일
기본 완료 (추정된)
기본 완료
2026년 12월 1일
연구 완료 (추정된)
연구 완료
2026년 12월 1일
연구 등록 날짜
최초 제출
최초 제출
2026년 7월 15일
QC 기준을 충족하는 최초 제출
QC 기준을 충족하는 최초 제출
2026년 7월 15일
처음 게시됨 (실제)
처음 게시됨
2026년 7월 20일
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
마지막 업데이트 게시됨
2026년 7월 28일
QC 기준을 충족하는 마지막 업데이트 제출
QC 기준을 충족하는 마지막 업데이트 제출
2026년 7월 27일
마지막으로 확인됨
마지막으로 확인됨
2026년 7월 1일
추가 정보
이 연구와 관련된 용어
기타 연구 ID 번호
기타 연구 ID 번호
- FTK_2026_13
개별 참가자 데이터(IPD) 계획
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예
IPD 계획 설명
All IPD that underlie results in a publication.
IPD 공유 기간
Beginning 1 month after the publication of results with no end date.
IPD 공유 액세스 기준
Anonymized IPD will be uploaded to an open-access data repository.
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