American academic medical center studies a Comparison of Toxicities Between Proton Therapy and IMRT for Post Operative Treatment of Endometrial or Cervical Cancers
The company Mayo Clinic is commencing recruitment for the clinical trial of the Comparison of Toxicities Between Proton Therapy and IMRT for Post Operative Treatment of Endometrial or Cervical Cancers.
The conditions are Cervical Cancer, Endometrial Cancer.
A new clinical trial is recruiting patients in the following locations: United States.
The trial officially began on the December 7, 2020 and is planned to complete on December 2023.
This trial is designed as a pilot trial to study, in a preliminary fashion, whether proton radiation therapy (proton RT) reduces acute gastrointestinal toxicities at the end of treatment compared to intensity modulated radiation therapy (IMRT).
The population that can be enrolled into this study includes the patients treated with proton RT or intensity modulated radiation therapy post operative for treatment of endometrial or cervical cancer.
The inclusion parameters are:
- Age ≥ 18 years
- Histologically confirmed diagnosis of cervical or endometrial cancer
- Must have undergone an open or robotic hysterectomy (total abdominal, vaginal, radical, or total laparoscopic) for carcinoma of the cervix or endometrium
- Planned to receive either proton or IMRT radiation treatment, with use of rectal balloon, at an IRB-approved Mayo Clinic site
- Plan for RT to pelvis with or without para-aortic lymph node irradiation
- If received high-dose chemotherapy prior to registration, last dose must have been given
The full list can be viewed at the link below.
Mayo Clinic is a nonprofit American academic medical center focused on integrated health care, education, and research. It employs over 4,500 physicians and scientists, along with another 58,400 administrative and allied health staff, across three major campuses: Rochester, Minnesota; Jacksonville, Florida; and Phoenix/Scottsdale, Arizona. The practice specializes in treating difficult cases through tertiary care and destination medicine. It is home to the top-ten ranked Mayo Clinic Alix School of Medicine in addition to many of the highest regarded residency education programs in the United States. It spends over $660 million a year on research and has more than 3,000 full-time research personnel.
The link to the complete study profile: https://ichgcp.net/clinical-trials-registry/NCT04745650
