Study Evaluating the Olfactory Recovery of Anosmia Post COVID-19 by Olfactory Rehabilitation Assisted by Web-application begins in France

Photo by Kristine Wook

The company Weprom is conducting the clinical trial Study Evaluating the Olfactory Recovery of Anosmia Post COVID-19 by Olfactory Rehabilitation Assisted by Web-application (COVIDANOSMIA).

Kelindi, Centre National de la Recherche Scientifique, France, and Hospital of Tours are the collaborators in this study.

Anosmia is a symptom present in 40 to 80% of patients and usually only lasts 1 to 2 weeks. However, in nearly one in five patients, it can last beyond or even several months with consequences in terms of undernutrition and depression. However, olfactory rehabilitation is a technique validated in post-infectious anosmia since 2014 and recommended by international learned societies to accelerate recovery with nearly 63% improvement in anosmia In the context of the health crisis linked to the coronavirus, approximately 1 million French people will have persistent anosmia following an infection with COVID-19. A web-application to support the olfactory coaching of anosmic patients and help with follow-up seems relevant to promote recovery and the proper conduct of this coaching.

It is planned to include 700 participants.

Actual study start date is February 1, 2021. The researchers expect to complete the study by August 1, 2021.

Among study population are all users of the application who have not objected to the use of their data.

There are a number of conditions that do not allow participation, such as:

  • Other causes of anosmia than COVID
  • Contraindication to olfactory coaching (allergy to one of the aromatic oils)
  • Minor

The location of the study is as follows (further details can be found here https://ichgcp.net/clinical-trials-registry/NCT04806880) Le Mans, France.

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