The study to evaluate shockwave therapy in combination platelet rich plasma to treat erectile dysfunction in diabetic men

The research company University of Miami is conducting the clinical trial Combining Shockwave Therapy and Platelet Rich Plasma to Treat Erectile Dysfunction in Diabetic Men (COCKTAIL-DM) (COCKTAIL-DM).

The purpose of this research study is to evaluate whether the combination of Shockwave Therapy (SWT) with Platelet Rich Plasma (PRP) is synergistic and can reverse the pathology of microvascular Erectile Dysfunction (ED) and enhance erectile function in diabetics patients.

It is planned to include 15 participants.

Actual study start date is October 1, 2022. The researchers expect to complete the study by May 1, 2024.

One primary outcome measure is Changes in endothelial function markers, Markers of endothelial function will include Vascular Endothelial Growth Factor (VEGF), Stromal cell-derived factor 1 (SDF-1α), and Stem Cell Factor (SCF). All measured from serum blood samples in units of pg/mL.

Further details can be found here: https://ichgcp.net/clinical-trials-registry/NCT05525572.