- ICH GCP
- Register voor klinische proeven in de VS.
- Klinische proef NCT07608575
Trunk and Lower Limb Muscle Contributions to ACL Loading During Single-Leg Landing
Studie Overzicht
Toestand
Conditie
Gedetailleerde beschrijving
Anterior cruciate ligament injuries often led to long-term consequences including early knee osteoarthritis, abnormal neuromuscular function, and reduced athletic participation. Approximately 70% of ACL injuries occurred via non-contact mechanisms, frequently during single-leg landing tasks. During such movements, ACL loading was influenced by joint kinematics, external forces, and neuromuscular coordination of both trunk and lower limb muscles. This study adopted a two-level approach. First, standard biomechanical analyses were conducted to evaluate the relationship between functional core strength and knee joint biomechanics, including knee valgus angle and knee abduction moment during SLL. Second, a musculoskeletal modelling approach was employed to quantify the contribution of individual trunk and lower limb muscles to ACL loading.
Participants performed standardized single-leg landing tasks while wearing inertial motion sensors and surface electromyography electrodes. Ground reaction forces were recorded using a force platform. A full-body musculoskeletal model was scaled to participant anthropometry and used to estimate muscle forces and ACL loading during the landing phase. Statistical analyses included linear regression and linear mixed-effects modelling to examine relationships between muscle forces, knee biomechanics, and ACL loading.
Studietype
Inschrijving (Werkelijk)
Contacten en locaties
Studie Locaties
-
-
Pulau Pinang
-
Nibong Tebal, Pulau Pinang, Maleisië
- School of Mechanical Engineering, Universiti Sains Malaysia
-
-
Deelname Criteria
Geschiktheidscriteria
Leeftijden die in aanmerking komen voor studie
- Volwassen
Accepteert gezonde vrijwilligers
Bemonsteringsmethode
Studie Bevolking
Beschrijving
Inclusion Criteria:
- Male collegiate athletes aged 19-25 years
- Minimum of 3 years of competitive experience in jump-landing sports (e.g., volleyball, basketball, netball)
- Training frequency of at least twice per week
- No history of back or lower limb injury
Exclusion Criteria:
- History of major lower limb or back injury requiring surgery
- Any medical condition preventing maximal physical effort
- Current musculoskeletal pain or injury affecting movement performance
Studie plan
Hoe is de studie opgezet?
Ontwerpdetails
Wat meet het onderzoek?
Primaire uitkomstmaten
Uitkomstmaat |
Maatregel Beschrijving |
Tijdsspanne |
|---|---|---|
|
Peak Anterior Cruciate Ligament (ACL) Force During Single-Leg Landing
Tijdsspanne: Assessed during a single laboratory testing session (up to 2 hours).
|
Peak anterior cruciate ligament (ACL) force (Newtons, N) was estimated during the landing phase of a single-leg landing task using subject-specific musculoskeletal modelling.
Three-dimensional whole-body kinematics (Xsens inertial motion capture), ground reaction forces (Bertec force platform), and surface electromyography (EMG) signals from trunk and lower limb muscles were integrated within a full-body musculoskeletal model to compute ACL loading.
Peak ACL force was extracted from initial ground contact to maximum knee flexion.
|
Assessed during a single laboratory testing session (up to 2 hours).
|
|
Correlation Between Plank Endurance Time and Peak Knee Valgus Angle During Single-Leg Landing
Tijdsspanne: Assessed during a single laboratory testing session (up to 2 hours).
|
Pearson correlation between plank endurance time (seconds) and peak knee valgus angle (degrees) measured during single-leg landing using three-dimensional motion analysis (Xsens inertial motion capture).
|
Assessed during a single laboratory testing session (up to 2 hours).
|
|
Knee Valgus Angle During Single-Leg Landing
Tijdsspanne: Assessed during a single laboratory testing session (up to 2 hours).
|
Peak knee valgus angle (degrees, °) was calculated from three-dimensional lower limb kinematic data collected using full-body inertial motion capture (Xsens).
Knee joint angles were derived using inverse kinematics and analyzed from initial ground contact to maximum knee flexion during the single-leg landing task.
|
Assessed during a single laboratory testing session (up to 2 hours).
|
|
Knee Abduction Moment During Single-Leg Landing
Tijdsspanne: Assessed during a single laboratory testing session (up to 2 hours).
|
Peak knee abduction moment (Newton-meters, Nm) was computed using inverse dynamics based on synchronized three-dimensional kinematic data (Xsens) and ground reaction force data (Bertec force platform).
Peak values were identified during the landing phase from initial ground contact to maximum knee flexion.
|
Assessed during a single laboratory testing session (up to 2 hours).
|
|
Trunk and Lower Limb Muscle Forces During Single-Leg Landing
Tijdsspanne: Assessed during a single laboratory testing session (up to 2 hours).
|
Peak trunk and lower limb muscle forces (Newtons, N) were estimated using a full-body lumbar spine musculoskeletal model driven by experimental kinematics, ground reaction forces, and electromyography-informed muscle activation patterns.
Muscle force outputs were analyzed during the landing phase of the single-leg landing task from initial ground contact to maximum knee flexion.
|
Assessed during a single laboratory testing session (up to 2 hours).
|
Medewerkers en onderzoekers
Sponsor
Studie record data
Bestudeer belangrijke data
Studie start (Werkelijk)
Primaire voltooiing (Werkelijk)
Studie voltooiing (Werkelijk)
Studieregistratiedata
Eerst ingediend
Eerst ingediend dat voldeed aan de QC-criteria
Eerst geplaatst (Werkelijk)
Updates van studierecords
Laatste update geplaatst (Werkelijk)
Laatste update ingediend die voldeed aan QC-criteria
Laatst geverifieerd
Meer informatie
Termen gerelateerd aan deze studie
Andere studie-ID-nummers
- USM/JEPeM/KK/23100759
Informatie over medicijnen en apparaten, studiedocumenten
Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel
Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct
Deze informatie is zonder wijzigingen rechtstreeks van de website clinicaltrials.gov gehaald. Als u verzoeken heeft om uw onderzoeksgegevens te wijzigen, te verwijderen of bij te werken, neem dan contact op met register@clinicaltrials.gov. Zodra er een wijziging wordt doorgevoerd op clinicaltrials.gov, wordt deze ook automatisch bijgewerkt op onze website .