- ICH GCP
- Реестр клинических исследований США
- Клиническое испытание NCT07608575
Trunk and Lower Limb Muscle Contributions to ACL Loading During Single-Leg Landing
Обзор исследования
Статус
Условия
Подробное описание
Anterior cruciate ligament injuries often led to long-term consequences including early knee osteoarthritis, abnormal neuromuscular function, and reduced athletic participation. Approximately 70% of ACL injuries occurred via non-contact mechanisms, frequently during single-leg landing tasks. During such movements, ACL loading was influenced by joint kinematics, external forces, and neuromuscular coordination of both trunk and lower limb muscles. This study adopted a two-level approach. First, standard biomechanical analyses were conducted to evaluate the relationship between functional core strength and knee joint biomechanics, including knee valgus angle and knee abduction moment during SLL. Second, a musculoskeletal modelling approach was employed to quantify the contribution of individual trunk and lower limb muscles to ACL loading.
Participants performed standardized single-leg landing tasks while wearing inertial motion sensors and surface electromyography electrodes. Ground reaction forces were recorded using a force platform. A full-body musculoskeletal model was scaled to participant anthropometry and used to estimate muscle forces and ACL loading during the landing phase. Statistical analyses included linear regression and linear mixed-effects modelling to examine relationships between muscle forces, knee biomechanics, and ACL loading.
Тип исследования
Регистрация (Действительный)
Контакты и местонахождение
Места учебы
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Pulau Pinang
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Nibong Tebal, Pulau Pinang, Малайзия
- School of Mechanical Engineering, Universiti Sains Malaysia
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Критерии участия
Критерии приемлемости
Возраст, подходящий для обучения
- Взрослый
Принимает здоровых добровольцев
Метод выборки
Исследуемая популяция
Описание
Inclusion Criteria:
- Male collegiate athletes aged 19-25 years
- Minimum of 3 years of competitive experience in jump-landing sports (e.g., volleyball, basketball, netball)
- Training frequency of at least twice per week
- No history of back or lower limb injury
Exclusion Criteria:
- History of major lower limb or back injury requiring surgery
- Any medical condition preventing maximal physical effort
- Current musculoskeletal pain or injury affecting movement performance
Учебный план
Как устроено исследование?
Детали дизайна
Что измеряет исследование?
Первичные показатели результатов
Мера результата |
Мера Описание |
Временное ограничение |
|---|---|---|
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Peak Anterior Cruciate Ligament (ACL) Force During Single-Leg Landing
Временное ограничение: Assessed during a single laboratory testing session (up to 2 hours).
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Peak anterior cruciate ligament (ACL) force (Newtons, N) was estimated during the landing phase of a single-leg landing task using subject-specific musculoskeletal modelling.
Three-dimensional whole-body kinematics (Xsens inertial motion capture), ground reaction forces (Bertec force platform), and surface electromyography (EMG) signals from trunk and lower limb muscles were integrated within a full-body musculoskeletal model to compute ACL loading.
Peak ACL force was extracted from initial ground contact to maximum knee flexion.
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Assessed during a single laboratory testing session (up to 2 hours).
|
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Correlation Between Plank Endurance Time and Peak Knee Valgus Angle During Single-Leg Landing
Временное ограничение: Assessed during a single laboratory testing session (up to 2 hours).
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Pearson correlation between plank endurance time (seconds) and peak knee valgus angle (degrees) measured during single-leg landing using three-dimensional motion analysis (Xsens inertial motion capture).
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Assessed during a single laboratory testing session (up to 2 hours).
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Knee Valgus Angle During Single-Leg Landing
Временное ограничение: Assessed during a single laboratory testing session (up to 2 hours).
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Peak knee valgus angle (degrees, °) was calculated from three-dimensional lower limb kinematic data collected using full-body inertial motion capture (Xsens).
Knee joint angles were derived using inverse kinematics and analyzed from initial ground contact to maximum knee flexion during the single-leg landing task.
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Assessed during a single laboratory testing session (up to 2 hours).
|
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Knee Abduction Moment During Single-Leg Landing
Временное ограничение: Assessed during a single laboratory testing session (up to 2 hours).
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Peak knee abduction moment (Newton-meters, Nm) was computed using inverse dynamics based on synchronized three-dimensional kinematic data (Xsens) and ground reaction force data (Bertec force platform).
Peak values were identified during the landing phase from initial ground contact to maximum knee flexion.
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Assessed during a single laboratory testing session (up to 2 hours).
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Trunk and Lower Limb Muscle Forces During Single-Leg Landing
Временное ограничение: Assessed during a single laboratory testing session (up to 2 hours).
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Peak trunk and lower limb muscle forces (Newtons, N) were estimated using a full-body lumbar spine musculoskeletal model driven by experimental kinematics, ground reaction forces, and electromyography-informed muscle activation patterns.
Muscle force outputs were analyzed during the landing phase of the single-leg landing task from initial ground contact to maximum knee flexion.
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Assessed during a single laboratory testing session (up to 2 hours).
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Соавторы и исследователи
Спонсор
Даты записи исследования
Изучение основных дат
Начало исследования (Действительный)
Первичное завершение (Действительный)
Завершение исследования (Действительный)
Даты регистрации исследования
Первый отправленный
Впервые представлено, что соответствует критериям контроля качества
Первый опубликованный (Действительный)
Обновления учебных записей
Последнее опубликованное обновление (Действительный)
Последнее отправленное обновление, отвечающее критериям контроля качества
Последняя проверка
Дополнительная информация
Термины, связанные с этим исследованием
Другие идентификационные номера исследования
- USM/JEPeM/KK/23100759
Информация о лекарствах и устройствах, исследовательские документы
Изучает лекарственный продукт, регулируемый FDA США.
Изучает продукт устройства, регулируемый Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов США.
Эта информация была получена непосредственно с веб-сайта clinicaltrials.gov без каких-либо изменений. Если у вас есть запросы на изменение, удаление или обновление сведений об исследовании, обращайтесь по адресу register@clinicaltrials.gov. Как только изменение будет реализовано на clinicaltrials.gov, оно будет автоматически обновлено и на нашем веб-сайте. .