Anterior segment optical coherence tomography for evaluation of cornea and ocular surface

Mittanamalli S Sridhar, Raul Martin, Mittanamalli S Sridhar, Raul Martin

Abstract

Current corneal assessment technologies make the process of corneal evaluation extremely fast and simple. Several devices and technologies allow to explore and manage patients better. Optical coherence tomography (OCT) technology has evolved over the years, and hence a detailed evaluation of anterior segment (AS) structures such as cornea, conjunctiva, tear meniscus, anterior chamber, iris, and crystalline lens has been possible in a noncontact and safe procedure. The purpose of this special issue is to present and update in the evaluation of cornea and ocular surface, and this paper reviews a description of the AS-OCT, presenting the technology and common clinical uses of OCT in the management of diseases involving cornea and ocular surface to provide an updated information of the clinical recommendations of this technique in eye care practice.

Keywords: Anterior eye; anterior segment-optical coherence tomography; cornea; dystrophy; keratoconus; ocular surface; tear film.

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Anterior segment-optical coherence tomography of acute corneal hydrops showing Descemet's membrane tear and intrastromal cleft
Figure 2
Figure 2
Anterior segment-optical coherence tomography of same patient showing healing in response to injection of C3F8 gas
Figure 3
Figure 3
Anterior segment-optical coherence tomography of the same patient following healing of Descemet's membrane tear. Note the scleral contact lens
Figure 4
Figure 4
Anterior segment-optical coherence tomography of fungal keratitis
Figure 5
Figure 5
Anterior segment-optical coherence tomography of a patient with Wilson disease showing Kayser–Fleischer ring as hyperreflectivity of peripheral Descemet's membrane
Figure 6
Figure 6
Anterior segment-optical coherence tomography of patient with systemic sclerosis showing Descemet's membrane scarring and corneal edema

References

    1. Doors M, Berendschot TT, de Brabander J, Webers CA, Nuijts RM. Value of optical coherence tomography for anterior segment surgery. J Cataract Refract Surg. 2010;36:1213–29.
    1. Izatt JA, Hee MR, Swanson EA, Lin CP, Huang D, Schuman JS, et al. Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography. Arch Ophthalmol. 1994;112:1584–9.
    1. Ramos JL, Li Y, Huang D. Clinical and research applications of anterior segment optical coherence tomography – A review. Clin Exp Ophthalmol. 2009;37:81–9.
    1. Gumus K, Pflugfelder SC. Anterior segment optical coherence tomography (AS-OCT) in the management of dry eye. Int Ophthalmol Clin. 2017;57:13–22.
    1. Thomas BJ, Galor A, Nanji AA, El Sayyad F, Wang J, Dubovy SR, et al. Ultra high-resolution anterior segment optical coherence tomography in the diagnosis and management of ocular surface squamous neoplasia. Ocul Surf. 2014;12:46–58.
    1. Wang C, Xia X, Wang F, Ye S, Zhou S. Determination of surgical strategies for burn-induced conjunctivalized corneas using optical coherence tomography. Cornea. 2015;34:1233–9.
    1. Vazirani J, Ali MH, Sharma N, Gupta N, Mittal V, Atallah M, et al. Autologous simple limbal epithelial transplantation for unilateral limbal stem cell deficiency: Multicentre results. Br J Ophthalmol. 2016;100:1416–20.
    1. Zakaria N, Ní Dhubhghaill S, Taal M, Berneman Z, Koppen C, Tassignon MJ, et al. Optical coherence tomography in cultivated limbal epithelial stem cell transplantation surgery. Asia Pac J Ophthalmol (Phila) 2015;4:339–45.
    1. Majander AS, Lindahl PM, Vasara LK, Krootila K. Anterior segment optical coherence tomography in congenital corneal opacities. Ophthalmology. 2012;119:2450–7.
    1. Lee H, Proudlock FA, Gottlob I. Pediatric optical coherence tomography in clinical practice-recent progress. Invest Ophthalmol Vis Sci. 2016;57:OCT69–79.
    1. Pavlin CJ, Vásquez LM, Lee R, Simpson ER, Ahmed II. Anterior segment optical coherence tomography and ultrasound biomicroscopy in the imaging of anterior segment tumors. Am J Ophthalmol. 2009;147:214–900.
    1. Pong JC, Lai JS. Imaging of primary cyst of the iris pigment epithelium using anterior segment OCT and ultrasonic biomicroscopy. Clin Exp Optom. 2009;92:139–41.
    1. Lara-Medina FJ, Ispa-Callén MC, Núñez A, López-Romero S, López-Mondéjar E, Zarco JM, et al. Exploration of the anterior segment by optical coherence tomography-3. Arch Soc Esp Oftalmol. 2006;81:647–52.
    1. Skalet AH, Li Y, Lu CD, Jia Y, Lee B, Husvogt L, et al. Optical coherence tomography angiography characteristics of iris melanocytic tumors. Ophthalmology. 2017;124:197–204.
    1. Kymionis GD, Tsoulnaras KI, Grentzelos MA, Plaka AD, Mikropoulos DG, Liakopoulos DA, et al. Corneal stroma demarcation line after standard and high-intensity collagen crosslinking determined with anterior segment optical coherence tomography. J Cataract Refract Surg. 2014;40:736–40.
    1. Kanellopoulos AJ, Asimellis G. OCT-derived comparison of corneal thickness distribution and asymmetry differences between normal and keratoconic eyes. Cornea. 2014;33:1274–81.
    1. Steinberg J, Casagrande MK, Frings A, Katz T, Druchkiv V, Richard G, et al. Screening for subclinical keratoconus using swept-source fourier domain anterior segment optical coherence tomography. Cornea. 2015;34:1413–9.
    1. Shahhoseini S, Hashemi H, Asgari S. Intracorneal ring segment depth in keratoconus patients: A long-term follow-up study. Int Ophthalmol. 2017;12:1–5.
    1. Ueno H, Matuzawa A, Kumagai Y, Takagi H, Ueno S. Imaging of a severe case of acute hydrops in a patient with keratoconus using anterior segment optical coherence tomography. Case Rep Ophthalmol. 2012;3:304–10.
    1. Titiyal JS, Rathi A, Kaur M, Falera R. AS-OCT as a rescue tool during difficult lenticule extraction in SMILE. J Refract Surg. 2017;33:352–4.
    1. Tang M, Wang L, Koch DD, Li Y, Huang D. Intraocular lens power calculation after previous myopic laser vision correction based on corneal power measured by fourier-domain optical coherence tomography. J Cataract Refract Surg. 2012;38:589–94.
    1. Packer M. Meta-analysis and review: Effectiveness, safety, and central port design of the intraocular collamer lens. Clin Ophthalmol. 2016;10:1059–77.
    1. Ju Y, Gao XW, Ren B. Posterior chamber phakic intraocular lens implantation for high myopia. Int J Ophthalmol. 2013;6:831–5.
    1. Liu Q, Zhou YH, Zhang J, Zheng Y, Zhai CB, Liu J, et al. Comparison of corneal flaps created by wavelight FS200 and intralase FS60 femtosecond lasers. Int J Ophthalmol. 2016;9:1006–10.
    1. Konstantopoulos A, Kuo J, Anderson D, Hossain P. Assessment of the use of anterior segment optical coherence tomography in microbial keratitis. Am J Ophthalmol. 2008;146:534–42.
    1. Abbouda A, Estrada AV, Rodriguez AE, Alió JL. Anterior segment optical coherence tomography in evaluation of severe fungal keratitis infections treated by corneal crosslinking. Eur J Ophthalmol. 2014;24:320–4.
    1. Yokogawa H, Kobayashi A, Yamazaki N, Sugiyama K. In vivo imaging of coin-shaped lesions in cytomegalovirus corneal endotheliitis by anterior segment optical coherence tomography. Cornea. 2014;33:1332–5.
    1. Sridhar MS. Advantages of anterior segment optical coherence tomography evaluation of the kayser-fleischer ring in wilson disease. Cornea. 2017;36:343–6.
    1. Lim SH. Clinical applications of anterior segment optical coherence tomography. J Ophthalmol. 2015;2015:605729.
    1. Zhou SY, Wang CX, Cai XY, Liu YZ. Anterior segment OCT-based diagnosis and management of descemet's membrane detachment. Ophthalmologica. 2012;227:215–22.
    1. Sharma N, Aron N, Kakkar P, Titiyal JS. Continuous intraoperative OCT guided management of post-deep anterior lamellar keratoplasty descemet's membrane detachment. Saudi J Ophthalmol. 2016;30:133–6.
    1. Miyakoshi A, Ozaki H, Otsuka M, Hayashi A. Efficacy of intraoperative anterior segment optical coherence tomography during descemet's stripping automated endothelial keratoplasty. ISRN Ophthalmol. 2014;2014:562062.
    1. Shazly TA, To LK, Conner IP, Espandar L. Intraoperative optical coherence tomography-assisted descemet stripping automated endothelial keratoplasty for anterior chamber fibrous ingrowth. Cornea. 2017;36:757–8.
    1. Zarei-Ghanavati S, Betancurt C, Mas AM, Wang J, Perez VL. Ultra high resolution optical coherence tomography in boston type I keratoprosthesis. J Ophthalmic Vis Res. 2015;10:26–32.
    1. Kang JJ, Allemann N, Vajaranant TS, de la Cruz J, Cortina MS. Anterior segment optical coherence tomography for the quantitative evaluation of the anterior segment following boston keratoprosthesis. PLoS One. 2013;8:e70673.
    1. Shapiro BL, Cortés DE, Chin EK, Li JY, Werner JS, Redenbo E, et al. High-resolution spectral domain anterior segment optical coherence tomography in type 1 boston keratoprosthesis. Cornea. 2013;32:951–5.
    1. Siebelmann S, Scholz P, Sonnenschein S, Bachmann B, Matthaei M, Cursiefen C, et al. Anterior segment optical coherence tomography for the diagnosis of corneal dystrophies according to the IC3D classification. Surv Ophthalmol. 2017;9:S0039.
    1. Batur M, Seven E, Tekin S, Yasar T. Anterior lens capsule and iris thicknesses in pseudoexfoliation syndrome. Curr Eye Res. 2017;14:1–5.
    1. Zheng X, Sakai H, Goto T, Namiguchi K, Mizoue S, Shiraishi A, et al. Anterior segment optical coherence tomography analysis of clinically unilateral pseudoexfoliation syndrome: Evidence of bilateral involvement and morphologic factors related to asymmetry. Invest Ophthalmol Vis Sci. 2011;52:5679–84.
    1. Hirnschall N, Buehren T, Bajramovic F, Trost M, Teuber T, Findl O, et al. Prediction of postoperative intraocular lens tilt using swept-source optical coherence tomography. J Cataract Refract Surg. 2017;43:732–6.
    1. Lee H, Kim EK, Kim HS, Kim TI. Fourier-domain optical coherence tomography evaluation of clear corneal incision structure according to blade material. J Cataract Refract Surg. 2014;40:1615–24.
    1. Elkady B, Piñero D, Alió JL. Corneal incision quality: Microincision cataract surgery versus microcoaxial phacoemulsification. J Cataract Refract Surg. 2009;35:466–74.
    1. Jung KI, Lim SA, Park HY, Park CK. Visualization of blebs using anterior-segment optical coherence tomography after glaucoma drainage implant surgery. Ophthalmology. 2013;120:978–83.
    1. Martin R, de Juan V, Rodríguez G, Cuadrado R, Fernandez I. Measurement of corneal swelling variations without removal of the contact lens during extended wear. Invest Ophthalmol Vis Sci. 2007;48:3043–50.
    1. Bandlitz S, Bäumer J, Conrad U, Wolffsohn J. Scleral topography analysed by optical coherence tomography. Cont Lens Anterior Eye. 2017;40:242–7.

Source: PubMed

3
Abonnere