Successful Treatment of Prosthetic Joint Infection due to Vancomycin-resistant Enterococci with Tedizolid

Sheng Si, Michael J Durkin, Maureen M Mercier, Melanie L Yarbrough, Stephen Y Liang, Sheng Si, Michael J Durkin, Maureen M Mercier, Melanie L Yarbrough, Stephen Y Liang

Abstract

Few antibiotic options exist for the management of infections due to vancomycin-resistant enterococci (VRE). We describe a case involving the safe and successful use of tedizolid, a new oxazolidinone, to treat VRE prosthetic joint infection.

Keywords: prosthetic joint infection; tedizolid; vancomycin-resistant enterococci.

Conflict of interest statement

Potential conflicts of interest: S.Y.L. serves as a sub-investigator for institutional research studies sponsored by Cepheid. M.J.D. has received royalties for the development of education materials for Medscape, funded in part by Merck. S.S., M.L.Y., and M.M.M. have no reported conflicts.

Figures

Figure 1
Figure 1
Case timeline, including surgeries, operative cultures, and antimicrobial therapy. CONS: coagulase-negative staphylococci

Source: PubMed

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