Influence of Literacy, Self-Efficacy, and Social Support on Diabetes-Related Outcomes Following Hospital Discharge

Audrey White, Elizabeth Buschur, Cara Harris, Michael L Pennell, Adam Soliman, Kathleen Wyne, Kathleen M Dungan, Audrey White, Elizabeth Buschur, Cara Harris, Michael L Pennell, Adam Soliman, Kathleen Wyne, Kathleen M Dungan

Abstract

Objective: To evaluate the relationship between health literacy, social support, and self-efficacy as predictors of change in A1c and readmission among hospitalized patients with type 2 diabetes (T2D).

Methods: This is a secondary analysis of patients with T2D (A1c >8.5%) enrolled in a randomized trial in which health literacy (Newest Vital Sign), social support (Multidimensional Scale of Perceived Social Support), and empowerment (Diabetes Empowerment Scale-Short Form) was assessed at baseline. Multivariable models evaluated whether these concepts were associated with A1c reduction at 12 weeks (absolute change, % with >1% reduction, % reaching individualized target) and readmission (14 and 30 days).

Results: A1c (N=108) decreased >1% in 60%, while individualized A1c target was achieved in 31%. After adjustment for baseline A1c and potential confounders, health literacy was associated with significant reduction in A1c (Estimate -0.21, 95% CI -0.40, -0.01, p=0.041) and >1% decrease in A1c (OR 1.37, 95% CI 1.08, 1.73, p=0.009). However, higher social support was associated with greater adjusted odds of reaching the individualized A1c target (OR 1.63, 95% CI 1.04, 2.55, p=0.32). Both higher empowerment (OR 0.23, 95% CI 0.08, 0.64, p=0.005) and social support (OR 0.57, 95% CI 0.36, 0.91, p=0.018) were associated with fewer readmissions by 14 days, but not 30 days.

Conclusion: The study indicates that health literacy and social support may be important predictors of A1c reduction post-discharge among hospitalized patients with T2D. Social support and diabetes self-management skills should be addressed and early follow-up may be critical for avoiding readmissions.

Clinical trial: NCT03455985.

Keywords: A1c; basal insulin; hospital discharge; literacy; readmission; self-efficacy; social support; type 2 diabetes.

Conflict of interest statement

KMD discloses research support from Novo Nordisk, Sanofi, Viacyte, Abbott, Dexcom, consulting with Eli Lilly, Novo Nordisk, Dexcom, Boehringer-Ingelheim, and Tolerion, and honorarium from UptoDate, Medscape, Med Learning Group, Integritas and Elsevier. MLP discloses research support from Pfizer and grant from Sanofi. EB discloses research support from Dexcom and Juvenile Diabetes Research Foundation. KW discloses research support: Sanofi & Allergan. Consulting: Novo; honorarium from Nova Biomedical. The authors report no other conflicts of interest in this work.

© 2022 White et al.

References

    1. Yang W, Dall TM, Beronjia K, et al. Economic costs of diabetes in the U.S. in 2017. Diabetes Care. 2018;41(5):917–928.
    1. Centers for Disease Control and Prevention website. Diabetes atlas; 2019. Available from: . Accessed July 28, 2022.
    1. Ali MK, Bullard KM, Saaddine JB, Cowie CC, Imperatore G, Gregg EW. Achievement of goals in U.S. diabetes care, 1999–2010. N Engl J Med. 2013;368(17):1613–1624. doi:10.1056/NEJMsa1213829
    1. Healy SJ, Black D, Harris C, Lorenz A, Dungan KM. Inpatient diabetes education is associated with less frequent hospital readmission among patients with poor glycemic control. Diabetes Care. 2013;36(10):2960–2967. doi:10.2337/dc13-0108
    1. National Committee for Quality Assurance website. Comprehensive diabetes care; 2020. Available from: . Accessed July 28, 2022.
    1. Carls GS, Huynh J, Tuttle E, Edelman SV. Achievement of glycated hemoglobin goals in the U.S. remains unchanged through 2014. Poster (1515-P) Presented at the 76th Scientific Sessions of the American Diabetes Association; 10–14 June 2016; New Orleans, LA.
    1. Dungan K, Lyons S, Manu K, et al. An individualized inpatient diabetes education and hospital transition program for poorly controlled hospitalized patients with diabetes. Endocr Pract. 2014;20(12):1265–1273. doi:10.4158/EP14061.OR
    1. Hill-Briggs F, Adler NE, Berkowitz SA, et al. Social determinants of health and diabetes: a scientific review. Diabetes Care. 2021;44(1):258–279.
    1. Cefalu WT, Rodgers GP. COVID-19 and metabolic diseases: a heightened awareness of health inequities and a renewed focus for research priorities. Cell Metab. 2021;33(3):473–478. doi:10.1016/j.cmet.2021.02.006
    1. Belanger MJ, Hill MA, Angelidi AM, Dalamaga M, Sowers JR, Mantzoros CS. Covid-19 and disparities in nutrition and obesity. N Engl J Med. 2020;383(11):e69. doi:10.1056/NEJMp2021264
    1. Walker RJ, Gebregziabher M, Martin-Harris B, Egede LE. Quantifying direct effects of social determinants of health on glycemic control in adults with type 2 diabetes. Diabetes Technol Ther. 2015;17(2):80–87. doi:10.1089/dia.2014.0166
    1. Walker RJ, Gebregziabher M, Martin-Harris B, Egede LE. Independent effects of socioeconomic and psychological social determinants of health on self-care and outcomes in Type 2 diabetes. Gen Hosp Psychiatry. 2014;36(6):662–668. doi:10.1016/j.genhosppsych.2014.06.011
    1. Al Sayah F, Majumdar SR, Williams B, Robertson S, Johnson JA. Health literacy and health outcomes in diabetes: a systematic review. J Gen Intern Med. 2013;28(3):444–452. doi:10.1007/s11606-012-2241-z
    1. White A, Bradley D, Buschur E, et al. Effectiveness of a diabetes focused electronic discharge orderset and post-discharge nursing support among poorly controlled hospitalized patients: a randomized controlled trial. JMIR Diabetes. 2022;7. doi:10.2196/33401
    1. Weiss BD, Mays MZ, Martz W, et al. Quick assessment of literacy in primary care: the newest vital sign. Ann Fam Med. 2005;3(6):514–522. doi:10.1370/afm.405
    1. Zimet GD, Dahlem NW, Zimet SG, Farley GK. The multidimensional scale of perceived social support. J Pers Assess. 1988;52(1):30–41. doi:10.1207/s15327752jpa5201_2
    1. Anderson RM, Fitzgerald JT, Gruppen LD, Funnell MM, Oh MS. The Diabetes Empowerment Scale-Short Form (DES-SF). Diabetes Care. 2003;26(5):1641–1642. doi:10.2337/diacare.26.5.1641-a
    1. Strom JL, Egede LE. The impact of social support on outcomes in adult patients with type 2 diabetes: a systematic review. Curr Diab Rep. 2012;12(6):769–781. doi:10.1007/s11892-012-0317-0
    1. Dahal PK, Hosseinzadeh H. Association of health literacy and diabetes self-management: a systematic review. Aust J Prim Health. 2019;25(6):526–533. doi:10.1071/PY19007
    1. Marciano L, Camerini A-L, Schulz PJ. The role of health literacy in diabetes knowledge, self-care, and glycemic control: a meta-analysis. J Gen Intern Med. 2019;34(6):1007–1017. doi:10.1007/s11606-019-04832-y
    1. Anderson ES, Winett RA, Wojcik JR. Self-regulation, self-efficacy, outcome expectations, and social support: social cognitive theory and nutrition behavior. Ann Behav Med. 2007;34(3):304–312. doi:10.1007/BF02874555
    1. Abdullah A, Liew SM, Salim H, Ng CJ, Chinna K. Prevalence of limited health literacy among patients with type 2 diabetes mellitus: a systematic review. PLoS One. 2019;14(5):e0216402. doi:10.1371/journal.pone.0216402
    1. Chima CC, Abdelaziz A, Asuzu C, Beech BM. Impact of health literacy on medication engagement among adults with diabetes in the United States: a systematic review. Diabetes Educ. 2020;46(4):335–349. doi:10.1177/0145721720932837
    1. Heine M, Lategan F, Erasmus M, et al. Health education interventions to promote health literacy in adults with selected non-communicable diseases living in low-to-middle income countries: a systematic review and meta-analysis. J Eval Clin Pract. 2021;27:1417–1428. doi:10.1111/jep.13554
    1. Tan JP, Cheng KKF, Siah RC-J. A systematic review and meta-analysis on the effectiveness of education on medication adherence for patients with hypertension, hyperlipidaemia and diabetes. J Adv Nurs. 2019;75(11):2478–2494. doi:10.1111/jan.14025
    1. Mohebi S, Parham M, Sharifirad G, Gharlipour Z, Mohammadbeigi A, Rajati F. Relationship between perceived social support and self-care behavior in type 2 diabetics: a cross-sectional study. J Educ Health Promot. 2018;7:48. doi:10.4103/jehp.jehp_73_17
    1. Chida Y, Hamer M. An association of adverse psychosocial factors with diabetes mellitus: a meta-analytic review of longitudinal cohort studies. Diabetologia. 2008;51(12):2168–2178. doi:10.1007/s00125-008-1154-1
    1. Flôr CR, Baldoni NR, Aquino JA, et al. What is the association between social capital and diabetes mellitus? A systematic review. Diabetes Metab Syndr Clin Res Rev. 2018;12(4):601–605. doi:10.1016/j.dsx.2018.03.021
    1. Walker RJ, Strom Williams J, Egede LE. Influence of race, ethnicity and social determinants of health on diabetes outcomes. Am J Med Sci. 2016;351(4):366–373. doi:10.1016/j.amjms.2016.01.008
    1. Mitchell SE, Sadikova E, Jack BW, Paasche-Orlow MK. Health literacy and 30-day postdischarge hospital utilization. J Health Commun. 2012;17(sup3):325–338. doi:10.1080/10810730.2012.715233
    1. Rubin DJ, Donnell-Jackson K, Jhingan R, Golden SH, Paranjape A. Early readmission among patients with diabetes: a qualitative assessment of contributing factors. J Diabetes Complications. 2014;28(6):869–873. doi:10.1016/j.jdiacomp.2014.06.013
    1. Sentell TL, Seto TB, Young MM, et al. Pathways to potentially preventable hospitalizations for diabetes and heart failure: a qualitative analysis of patient perspectives. BMC Health Serv Res. 2016;16:300. doi:10.1186/s12913-016-1511-6
    1. Wu EQ, Zhou S, Yu A, et al. Outcomes associated with insulin therapy disruption after hospital discharge among patients with type 2 diabetes mellitus who had used insulin before and during hospitalization. Endocr Pract. 2012;18(5):651–659. doi:10.4158/EP11314.OR
    1. Steinsbekk A, Rygg L, Lisulo M, Rise MB, Fretheim A. Group based diabetes self-management education compared to routine treatment for people with type 2 diabetes mellitus. A systematic review with meta-analysis. BMC Health Serv Res. 2012;12(1):213. doi:10.1186/1472-6963-12-213
    1. Qi L, Liu Q, Qi X, Wu N, Tang W, Xiong H. Effectiveness of peer support for improving glycaemic control in patients with type 2 diabetes: a meta-analysis of randomized controlled trials. BMC Public Health. 2015;15:471. doi:10.1186/s12889-015-1798-y
    1. Spencer-Bonilla G, Ponce OJ, Rodriguez-Gutierrez R, et al. A systematic review and meta-analysis of trials of social network interventions in type 2 diabetes. BMJ Open. 2017;7(8):e016506. doi:10.1136/bmjopen-2017-016506
    1. Zhang X, Yang S, Sun K, Fisher EB, Sun X. How to achieve better effect of peer support among adults with type 2 diabetes: a meta-analysis of randomized clinical trials. Patient Educ Couns. 2016;99(2):186–197. doi:10.1016/j.pec.2015.09.006
    1. Gómez-Velasco DV, Almeda-Valdes P, Martagón AJ, Galán-Ramírez GA, Aguilar-Salinas CA. Empowerment of patients with type 2 diabetes: current perspectives. Diabetes Metab Syndr Obes. 2019;12:1311–1321. doi:10.2147/DMSO.S174910
    1. Norris SL, Lau J, Smith SJ, Schmid CH, Engelgau MM. Self-management education for adults with type 2 diabetes: a meta-analysis of the effect on glycemic control. Diabetes Care. 2002;25(7):1159–1171. doi:10.2337/diacare.25.7.1159
    1. Beebe CA, Schmitt S. Engaging patients in education for self-management in an accountable care environment. Clin Diabetes. 2011;29(3):123–126. doi:10.2337/diaclin.29.3.123
    1. Haas L, Maryniuk M, Beck J, et al. National standards for diabetes self-management education and support. Diabetes Care. 2012;35(11):2393–2401. doi:10.2337/dc12-1707
    1. Aquino JA, Baldoni NR, Flôr CR, et al. Effectiveness of individual strategies for the empowerment of patients with diabetes mellitus: a systematic review with meta-analysis. Prim Care Diabetes. 2018;12(2):97–110. doi:10.1016/j.pcd.2017.10.004
    1. Baldoni NR, Aquino JA, Sanches-Giraud C, et al. Collective empowerment strategies for patients with Diabetes Mellitus: a systematic review and meta-analysis. Prim Care Diabetes. 2017;11(2):201–211. doi:10.1016/j.pcd.2016.09.006

Source: PubMed

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