The Efficacy and Cost-Effectiveness of Stepped Care Prevention and Treatment for Depressive and/or Anxiety Disorders: A Systematic Review and Meta-Analysis

Fiona Yan-Yee Ho, Wing-Fai Yeung, Tommy Ho-Yee Ng, Christian S Chan, Fiona Yan-Yee Ho, Wing-Fai Yeung, Tommy Ho-Yee Ng, Christian S Chan

Abstract

Stepped care is an increasingly popular treatment model for common mental health disorders, given the large discrepancy between the demand and supply of healthcare service available. In this review, we aim to compare the efficacy and cost-effectiveness of stepped care prevention and treatment with care-as-usual (CAU) or waiting-list control for depressive and/or anxiety disorders. 5 databases were utilized from its earliest available records up until April 2015. 10 randomized controlled trials were included in this review, of which 6 examined stepped care prevention and 4 examined stepped care treatment, specifically including ones regarding depressive and/or anxiety disorders. Only trials with self-help as a treatment component were included. Results showed stepped care treatment revealed a significantly better performance than CAU in reducing anxiety symptoms, and the treatment response rate of anxiety disorders was significantly higher in stepped care treatment than in CAU. No significant difference was found between stepped care prevention/treatment and CAU in preventing anxiety and/or depressive disorders and improving depressive symptoms. In conclusion, stepped care model appeared to be better than CAU in treating anxiety disorders. The model has the potential to reduce the burden on existing resources in mental health and increase the reach and availability of service.

Figures

Figure 1. Selection Flow of Trials for…
Figure 1. Selection Flow of Trials for Inclusion in the Review.
Figure 2. Stepped Care Treatment vs. CAU…
Figure 2. Stepped Care Treatment vs. CAU control on the Incidence of Anxiety and/or Depressive Disorders at Immediate Posttreatment.
Figure 3. Stepped Care Treatment vs. CAU…
Figure 3. Stepped Care Treatment vs. CAU control on Anxiety Symptoms at Immediate Posttreatment.

References

    1. Greenberg P. E. et al.. The economic burden of anxiety disorders in the 1990s. J. Clin Psychiatry. 60, 427–435 (1999).
    1. Simon G. E. Social and economic burden of mood disorders. Biol. Psychiatry. 54, 208–215 (2003).
    1. Ayers C. R., Sorrell J. T., Thorp S. R. & Wetherell J. L. Evidence-based psychological treatments for late-life anxiety. Psychol. Aging. 22, 8–17 (2007).
    1. Hollon S. D. & Ponniah K. A review of empirically supported psychological therapies for mood disorders in adults. Depress Anxiety. 27, 891–932 (2010).
    1. Kazdin A. E. Evidence-based treatment and practice: new opportunities to bridge clinical research and practice, enhance the knowledge base, and improve patient care. Am. Psychol. 63, 146–159 (2008).
    1. Horton R., Saxena S., Thornicroft G., Knapp M. & Whiteford H. Global mental health 2 Resources for mental health: scarcity, inequity, and inefficiency. Commentary. Lancet. 370, 878–889 (2007).
    1. Grant A., Townend M., Mulhern R. & Short N. in Cognitive behavioural therapy in mental health care. (Sage, 2010).
    1. Richards D. A. et al.. Delivering stepped care: an analysis of implementation in routine practice. Implement Sci. 7 (2012).
    1. Espie C. A. Stepped care”: A health technology solution for delivering cognitive behavioral therapy as a first line insomnia treatment. Sleep. 32, 1549–1558 (2009).
    1. Spek V. et al.. Internet-based cognitive behaviour therapy for symptoms of depression and anxiety: A meta-analysis. Psychol. Med. 37, 319–328 (2007).
    1. Anderson L. et al.. Self-help books for depression: How can practitioners and patients make the right choice. Br. J. Gen. Pract. 55, 387–392 (2012).
    1. Kunik M. E. et al.. COPD education and cognitive behavioral therapy group treatment for clinically significant symptoms of depression and anxiety in COPD patients: A randomized controlled trial. Psychol. Med. 38, 385–396 (2008).
    1. Stikkelbroek Y., Bodden D. H., Dekovi M. & van Baar A. L. Effectiveness and cost effectiveness of cognitive behavioral therapy (CBT) in clinically depressed adolescents: individual CBT versus treatment as usual (TAU). BMC Psychiatry. 13, 314 (2013).
    1. Baldessarini R. J. Drug therapy of depression and anxiety disorders in Goodman and Gilman’s the Pharmacological Basis of Therapeutics (eds Brunton L. L. et al..) 429–460 (McGraw-Hill, 2006).
    1. Bower P. & Gilbody S. Stepped care in psychological therapies: Access, effectiveness and efficiency. Br. J. Psychiatry. 186, 11–17 (2005).
    1. Muntingh A. et al.. Effectiveness of collaborative stepped care for anxiety disorders in primary care: A pragmatic cluster randomised controlled trial. Psychother Psychosom. 83, 37–44 (2014).
    1. Mitchell J. E. et al.. Stepped care and cognitive–behavioural therapy for bulimia nervosa: Randomised trial. Br. J. Psychiatry. 198, 391–397 (2011).
    1. Seekles W., van Straten A., Beekman A., van Marwijk H. & Cuijpers P. Stepped care treatment for depression and anxiety in primary care. A randomized controlled trial. Trials. 12, 171 (2011).
    1. Tolin D. F., Diefenbach G. J. & Gilliam C. M. Stepped care versus standard cognitive–behavioral therapy for obsessive–compulsive disorder: A preliminary study of efficacy and costs. Depress Anxiety. 28, 314–323 (2011).
    1. Zatzick D. et al.. A randomized stepped care intervention trial targeting posttraumatic stress disorder for surgically hospitalized injury survivors. Ann. Surg. 257, 390–399 (2013).
    1. Tummers M., Knoop H. & Bleijenberg G. Effectiveness of stepped care for chronic fatigue syndrome: A randomized noninferiority trial. J. Consult. Clin. Psychol. 78, 724–731 (2010).
    1. Cabezas C., Advani M., Puente D., Rodriguez-Blanco T. & Martin C. Effectiveness of a stepped primary care smoking cessation intervention: Cluster randomized clinical trial (ISTAPS study). Addiction. 106, 1696–1706 (2011).
    1. Drummond C. et al.. Effectiveness and cost-effectiveness of a stepped care intervention for alcohol use disorders in primary care: Pilot study. Br. J. Psychiatry. 195, 448–456 (2009).
    1. Crow S. J., Agras W. S., Fairburn C. G., Mitchell J. E. & Nyman J. A. A cost effectiveness analysis of stepped care treatment for bulimia nervosa. Int J Eat Disord. 46, 302–307 (2013).
    1. Jaehne A. et al.. The efficacy of stepped care models involving psychosocial treatment of alcohol use disorders and nicotine dependence: A systematic review of the literature. Curr Drug Abuse Rev. 5, 41–51 (2012).
    1. van Straten A., Hill J., Richards D. A. & Cuijpers P. Stepped care treatment delivery for depression: A systematic review and meta-analysis. Psychol. Med. 45, 231–246 (2015).
    1. van Boeijen C. A. et al.. Efficacy of self-help manuals for anxiety disorders in primary care: A systematic review. Fam. Pract. 22, 192–196 (2005).
    1. Scogin F. R., Hanson A. & Welsh D. Self-administered treatment in stepped-care models of depression treatment. J. Clin. Psychol. 59, 341–349 (2003).
    1. Higgins J. P. T. & Green S. In Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0. (The Cochrane Collaboration, 2011).
    1. Apil S. R., Hoencamp E., Judith Haffmans P. M. & Spinhoven P. A stepped care relapse prevention program for depression in older people: A randomized controlled trial. Int J Geriatr Psychiatry. 27, 583–591 (2012).
    1. Apil S. R. A., Spinhoven P., Haffmans P. M. J. & Hoencamp E. Two-year follow-up of a randomized controlled trial of stepped care cognitive behavioral therapy to prevent recurrence of depression in an older population. Int J Geriatr Psychiatry. 29, 317–325 (2014).
    1. Dozeman E. et al.. Contradictory effects for prevention of depression and anxiety in residents in homes for the elderly: A pragmatic randomized controlled trial. Int Psychogeriatr. 24, 1242–1251 (2012).
    1. van’t Veer-Tazelaar P. J. et al.. Stepped-care prevention of anxiety and depression in late life: A randomized controlled trial. Arch. Gen. Psychiatry. 66, 297–304 (2009).
    1. van’t Veer-Tazelaar P. J. et al.. Prevention of late-life anxiety and depression has sustained effects over 24 months: A pragmatic randomized trial. Am. J. Geriatric. 19, 230–239 (2011).
    1. Zhang D. X. et al.. Prevention of anxiety and depression in Chinese: A randomized clinical trial testing the effectiveness of a stepped care program in primary care. J Affect Disord. 169, 212–220 (2014).
    1. Oosterbaan D. B. et al.. Collaborative stepped care v. care as usual for common mental disorders: 8-month, cluster randomised controlled trial. Br. J. Psychiatry. 203, 132–139 (2013).
    1. Lewinsohn P. M., Antonuccio D. O., Breckenridge J. S. & Teri L. In The ‘Coping with Depression’ Course. (Castalia Publishing Companym 1984).
    1. Bosmans J. E. et al.. Cost-effectiveness of a stepped care programme to prevent depression and anxiety in residents in homes for the older people: A randomised controlled trial. Int. J. Geriatr. Psychiatry. 29, 182–190 (2014).
    1. van’t Veer-Tazelaar P. et al.. Cost-effectiveness of a stepped care intervention to prevent depression and anxiety in late life: Randomised trial. Br. J. Psychiatry. 196, 319-325. (2010).
    1. Altman D. G., Deeks J. J., Higgins J. P. T. & Thompson S. G. Measuring inconsistency in meta-analyses. BMJ. 327, 557–560 (2003).
    1. Cuijpers P. et al.. A meta-analysis of cognitive-behavioural therapy for adult depression, alone and in comparison with other treatments. Can. J. Psychiatry. 58, 376–385 (2013).
    1. Hofmann S. G. & Smits J. A. Cognitive-behavioral therapy for adult anxiety disorders: a meta-analysis of randomized placebo-controlled trials. J. Clin. Psychiatry. 69, 621–632 (2008).
    1. Bell A. C. & D’Zurilla T. J. Problem-solving therapy for depression: A meta-analysis. Clin Psychol Rev. 29, 348–353 (2009).
    1. Cuijpers P., van Straten A. & Warmerdam L. Behavioral activation treatments of depression: A meta-analysis. Clin Psychol Rev. 27, 318–326 (2007).
    1. Hofmann S. G., Sawyer A. T., Witt A. A. & Oh D. The effect of mindfulness-based therapy on anxiety and depression: A meta-analytic review. J. Consult. Clin. Psychol. 78, 169–183 (2010).
    1. Radloff L. S. The CES-D scale a self-report depression scale for research in the general population. Appl. Psychol. Meas. 1, 385–401 (1977).
    1. Beck A. T., Steer R. A. & Carbin M. G. Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation. Clin Psychol Rev. 8, 77–100 (1988b).
    1. Beck A. T., Epstein N., Brown G. & Steer R. A. An inventory for measuring clinical anxiety: Psychometric properties. J. Consult. Clin. Psychol. 56, 893–897 (1988a).
    1. Zigmond A. S. & Snaith R. P. The hospital anxiety and depression scale. Acta Psychiat. Scand. 67, 361–370 (1983).
    1. Luxton D. D., McCann R. A., Bush N. E., Mishkind M. C. & Reger G. M. Health for mental health: Integrating smartphone technology in behavioral healthcare. Prof Psychol Res Pr. 42, 505–512 (2011).
    1. Saxena S., Thornicroft G., Knapp M. & Whiteford H. Global mental heath 2:Resources for mental health: Scarcity, inequity, and inefficiency. The Lancet. 370, 878–889 (2007).

Source: PubMed

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