Usefulness of Adjunctive Fecal Calprotectin and Serum Procalcitonin in Individuals Positive for Clostridium difficile Toxin Gene by PCR Assay
Kristin Y Popiel, Romina Gheorghe, Jennifer Eastmond, Mark A Miller, Kristin Y Popiel, Romina Gheorghe, Jennifer Eastmond, Mark A Miller
Abstract
In 54/64 subjects with nosocomial diarrhea, fecal calprotectin levels correlated with the results of stool samples tested for Clostridium difficile toxin gene by PCR. Fecal calprotectin levels can be used as an adjunctive measure to PCR to support the diagnosis of C. difficile infection.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.
Figures
(A) Comparison of high-range fecal calprotectin levels correlated with the occurrence of C. difficile toxin gene detection by PCR in stool samples. (B) Receiver operating characteristic curve of high-range fecal calprotectin for predicting a positive C. difficile toxin gene assay by PCR (area under the curve, 0.82). CD-PCR, PCR assay for C. difficile toxin gene.
Source: PubMed