Tai Chi Is a Promising Exercise Option for Patients With Coronary Heart Disease Declining Cardiac Rehabilitation

Elena Salmoirago-Blotcher, Peter M Wayne, Shira Dunsiger, Julie Krol, Christopher Breault, Beth C Bock, Wen-Chih Wu, Gloria Y Yeh, Elena Salmoirago-Blotcher, Peter M Wayne, Shira Dunsiger, Julie Krol, Christopher Breault, Beth C Bock, Wen-Chih Wu, Gloria Y Yeh

Abstract

Background: More than 60% of patients decline participation in cardiac rehabilitation after a myocardial infarction. Options to improve physical activity (PA) and other risk factors in these high-risk individuals are limited. We conducted a phase 2 randomized controlled trial to determine feasibility, safety, acceptability, and estimates of effect of tai chi on PA, fitness, weight, and quality of life.

Methods and results: Patients with coronary heart disease declining cardiac rehabilitation enrollment were randomized to a "LITE" (2 sessions/week for 12 weeks) or to a "PLUS" (3 sessions/week for 12 weeks, then maintenance classes for 12 additional weeks) condition. PA (accelerometry), weight, and quality of life (Health Survey Short Form) were measured at baseline and 3, 6, and 9 months after baseline; aerobic fitness (stress test) was measured at 3 months. Twenty-nine participants (13 PLUS and 16 LITE) were enrolled. Retention at 9 months was 90% (LITE) and 88% (PLUS). No serious tai chi-related adverse events occurred. Significant mean between group differences in favor of the PLUS group were observed at 3 and 6 months for moderate-to-vigorous PA (100.33 min/week [95% confidence interval, 15.70-184.95 min/week] and 111.62 min/week; [95% confidence interval, 26.17-197.07 min/week], respectively, with a trend toward significance at 9 months), percentage change in weight, and quality of life. No changes in aerobic fitness were observed within and between groups.

Conclusions: In this community sample of patients with coronary heart disease declining enrollment in cardiac rehabilitation, a 6-month tai chi program was safe and improved PA, weight, and quality of life compared with a 3-month intervention. Tai chi could be an effective option to improve PA in this high-risk population.

Clinical trial registration: URL: http://www.clinicaltrials.gov. Unique identifier: NCT02165254.

Keywords: cardiac rehabilitation; coronary heart disease; physical exercise; risk factor; secondary prevention.

© 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

Figures

Figure 1
Figure 1
Consort diagram. LITE indicates 2 sessions/week for 12 weeks; PLUS, 3 sessions/week for 12 weeks, then maintenance classes for 12 additional weeks; and SAE, serious adverse event.
Figure 2
Figure 2
Unadjusted moderate‐to‐vigorous physical activity (MVPA), by study condition. LITE indicates 2 sessions/week for 12 weeks; and PLUS, 3 sessions/week for 12 weeks, then maintenance classes for 12 additional weeks.

References

    1. Bhatt DL, Eagle KA, Ohman EM, Hirsch AT, Goto S, Mahoney EM, Wilson PW, Alberts MJ, D'Agostino R, Liau CS, Mas JL, Röther J, Smith SC Jr, Salette G, Contant CF, Massaro JM, Steg PG; REACH Registry Investigators . Comparative determinants of 4‐year cardiovascular event rates in stable outpatients at risk of or with atherothrombosis. JAMA. 2010;304:1350–1357.
    1. Walker S, Asaria M, Manca A, Palmer S, Gale CP, Shah AD, Abrams KR, Crowther M, Timmis A, Hemingway H, Sculpher M. Long‐term healthcare use and costs in patients with stable coronary artery disease: a population‐based cohort using linked health records (CALIBER). Eur Heart J Qual Care Clin Outcomes. 2016;2:125–140.
    1. Baldacchino D. Myocardial infarction: a turning point in meaning in life over time. Br J Nurs. 2011;20:107–114.
    1. Dawood N, Vaccarino V, Reid KJ, Spertus JA, Hamid N, Parashar S. Predictors of smoking cessation after a myocardial infarction: the role of institutional smoking cessation programs in improving success. Arch Intern Med. 2008;168:1961–1967.
    1. Hu G, Tuomilehto J, Borodulin K, Jousilahti P. The joint associations of occupational, commuting, and leisure‐time physical activity, and the Framingham risk score on the 10‐year risk of coronary heart disease. Eur Heart J. 2007;28:492–498.
    1. Thompson PD, Buchner D, Pina IL, Balady GJ, Williams MA, Marcus BH, Berra K, Blair SN, Costa F, Franklin B, Fletcher GF, Gordon NF, Pate RR, Rodriguez BL, Yancey AK, Wenger NK. Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease. Circulation. 2003;107:3109–3116.
    1. Lee DC, Sui X, Artero EG, Lee IM, Church TS, McAuley PA, Stanford FC, Kohl HW III, Blair SN. Long‐term effects of changes in cardiorespiratory fitness and body mass index on all‐cause and cardiovascular disease mortality in men: the Aerobics Center Longitudinal Study. Circulation. 2011;124:2483–2490.
    1. Wessel TR, Arant CB, Olson MB, Johnson BD, Reis SE, Sharaf BL, Shaw LJ, Handberg E, Sopko G, Kelsey SF, Pepine CJ, Merz NB. Relationship of physical fitness vs body mass index with coronary artery disease and cardiovascular events in women. JAMA. 2004;292:1179–1187.
    1. Hammill BG, Curtis LH, Schulman KA, Whellan DJ. Relationship between cardiac rehabilitation and long‐term risks of death and myocardial infarction among elderly Medicare beneficiaries. Circulation. 2010;121:63–70.
    1. Heran BS, Chen JM, Ebrahim S, Moxham T, Oldridge N, Rees K, Thompson DR, Taylor RS. Exercise‐based cardiac rehabilitation for coronary heart disease. Cochrane Database Syst Rev. 2011;(7):CD001800.
    1. O'Connor GT, Buring JE, Yusuf S, Goldhaber SZ, Olmstead EM, Paffenbarger RS Jr, Hennekens CH. An overview of randomized trials of rehabilitation with exercise after myocardial infarction. Circulation. 1989;80:234–244.
    1. Goel K, Lennon RJ, Tilbury RT, Squires RW, Thomas RJ. Impact of cardiac rehabilitation on mortality and cardiovascular events after percutaneous coronary intervention in the community. Circulation. 2011;123:2344–2352.
    1. Kushner FG, Hand M, Smith SC Jr, King SB III, Anderson JL, Antman EM, Bailey SR, Bates ER, Blankenship JC, Casey DE Jr, Green LA, Hochman JS, Jacobs AK, Krumholz HM, Morrison DA, Ornato JP, Pearle DL, Peterson ED, Sloan MA, Whitlow PL, Williams DO. 2009 Focused updates: ACC/AHA guidelines for the management of patients with ST‐elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2009;120:2271–2306.
    1. Balady GJ, Ades PA, Bittner VA, Franklin BA, Gordon NF, Thomas RJ, Tomaselli GF, Yancy CW. Referral, enrollment, and delivery of cardiac rehabilitation/secondary prevention programs at clinical centers and beyond: a presidential advisory from the American Heart Association. Circulation. 2011;124:2951‐2960.
    1. Ades PA, Waldmann ML, Polk DM, Coflesky JT. Referral patterns and exercise response in the rehabilitation of female coronary patients aged greater than or equal to 62 years. Am J Cardiol. 1992;69:1422–1425.
    1. Ades PA, Waldmann ML, McCann WJ, Weaver SO. Predictors of cardiac rehabilitation participation in older coronary patients. Arch Intern Med. 1992;152:1033–1035.
    1. Jackson L, Leclerc J, Erskine Y, Linden W. Getting the most out of cardiac rehabilitation: a review of referral and adherence predictors. Heart. 2005;91:10–14.
    1. Grace SL, Gravely‐Witte S, Kayaniyil S, Brual J, Suskin N, Stewart DE. A multisite examination of sex differences in cardiac rehabilitation barriers by participation status. J Womens Health (Larchmt). 2009;18:209–216.
    1. Benz Scott LA, Ben‐Or K, Allen JK. Why are women missing from outpatient cardiac rehabilitation programs? A review of multilevel factors affecting referral, enrollment, and completion. J Womens Health (Larchmt). 2002;11:773–791.
    1. Scotto CJ, Waechter D, Rosneck J. Factors affecting program completion in phase II cardiac rehabilitation. Can J Cardiovasc Nurs. 2011;21:15–20.
    1. Wayne PM, Kaptchuk TJ. Challenges inherent to t'ai chi research, part I: t'ai chi as a complex multicomponent intervention. J Altern Complement Med. 2008;14:95–102.
    1. Fuzhong L, Harmer P, McAuley E, Duncan TE, Duncan SC, Chaumeton N, Fisher KJ. An evaluation of the effects of Tai Chi exercise on physical function among older persons: a randomized controlled trial. Ann Behav Med. 2001;23:139–146.
    1. Wayne PM, Berkowitz DL, Litrownik DE, Buring JE, Yeh GY. What do we really know about the safety of Tai Chi? A systematic review of adverse event reports in randomized trials. Arch Phys Med Rehabil. 2014;95:2470–2483.
    1. Jones AY, Dean E, Scudds RJ. Effectiveness of a community‐based Tai Chi program and implications for public health initiatives. Arch Phys Med Rehabil. 2005;86:619–625.
    1. Taylor‐Piliae RE, Haskell WL, Froelicher ES. Hemodynamic responses to a community‐based Tai Chi exercise intervention in ethnic Chinese adults with cardiovascular disease risk factors. Eur J Cardiovasc Nurs. 2006;5:165–174.
    1. Lan C, Chen SY, Lai JS. The exercise intensity of Tai Chi Chuan. Med Sport Sci. 2008;52:12–19.
    1. Zhuo D, Shephard RJ, Plyley MJ, Davis GM. Cardiorespiratory and metabolic responses during Tai Chi Chuan exercise. Can J Appl Sport Sci. 1984;9:7–10.
    1. Zheng G, Li S, Huang M, Liu F, Tao J, Chen L. The effect of Tai Chi training on cardiorespiratory fitness in healthy adults: a systematic review and meta‐analysis. PLoS One. 2015;10:e0117360.
    1. Yeh GY, McCarthy EP, Wayne PM, Stevenson LW, Wood MJ, Forman D, Davis RB, Phillips RS. Tai Chi exercise in patients with chronic heart failure: a randomized clinical trial. Arch Intern Med. 2011;171:750–757.
    1. Barrow DE, Bedford A, Ives G, O'Toole L, Channer KS. An evaluation of the effects of Tai Chi Chuan and Chi Kung training in patients with symptomatic heart failure: a randomised controlled pilot study. Postgrad Med J. 2007;83:717–721.
    1. Wang XQ, Pi YL, Chen PJ, Liu Y, Wang R, Li X, Chen BL, Zhu Y, Yang YJ, Niu ZB. Traditional Chinese exercise for cardiovascular diseases: systematic review and meta‐analysis of randomized controlled trials. J Am Heart Assoc. 2016;5:e002562 DOI: 10.1161/JAHA.115.002562.
    1. Blumenthal JA, Sherwood A, Smith PJ, Watkins L, Mabe S, Kraus WE, Ingle K, Miller P, Hinderliter A. Enhancing cardiac rehabilitation with stress management training: a randomized, clinical efficacy trial. Circulation. 2016;133:1341–1350.
    1. Salmoirago‐Blotcher E, Wayne P, Bock BC, Dunsiger S, Wu WC, Stabile L, Yeh G. Design and methods of the Gentle Cardiac Rehabilitation Study: a behavioral study of Tai Chi exercise for patients not attending cardiac rehabilitation. Contemp Clin Trials. 2015;43:243–251. DOI: 10.1016/j.cct.2015.06.020.
    1. Blair SN, Haskell WL, Ho P, Paffenbarger RS Jr, Vranizan KM, Farquhar JW, Wood PD. Assessment of habitual physical activity by a seven‐day recall in a community survey and controlled experiments. Am J Epidemiol. 1985;122:794–804.
    1. Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, Franklin BA, Macera CA, Heath GW, Thompson PD, Bauman A. Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc. 2007;39:1423–1434.
    1. Katzman R, Brown T, Fuld P, Peck A, Schechter R, Schimmel H. Validation of a short Orientation‐Memory‐Concentration Test of cognitive impairment. Am J Psychiatry. 1983;140:734–739.
    1. American College of Sports Medicine . Guidelines for Exercise Testing and Prescription. 6th ed Baltimore, MD: Lippincott Williams & Wilkins; 2000:22–32.
    1. Everitt B, Hothorn T. A Handbook of Statistical Analyses Using R. 2nd ed Boca Raton, FL: CRC Press; 2010.
    1. Yeh GY, Roberts DH, Wayne PM, Davis RB, Quilty MT, Phillips RS. Tai Chi exercise for patients with chronic obstructive pulmonary disease: a pilot study. Respir Care. 2010;55:1475–1482.
    1. Bellg AJ, Borrelli B, Resnick B, Hecht J, Minicucci DS, Ory M, Ogedegbe G, Orwig D, Ernst D, Czajkowski S. Enhancing treatment fidelity in health behavior change studies: best practices and recommendations from the NIH Behavior Change Consortium. Health Psychol. 2004;23:443–451.
    1. Thomas S, Reading J, Shephard RJ. Revision of the Physical Activity Readiness Questionnaire (PAR‐Q). Can J Sport Sci. 1992;17:338–345.
    1. Sloane R, Snyder DC, Demark‐Wahnefried W, Lobach D, Kraus WE. Comparing the 7‐day physical activity recall with a triaxial accelerometer for measuring time in exercise. Med Sci Sports Exerc. 2009;41:1334–1340.
    1. di Prampero PE, Salvadego D, Fusi S, Grassi B. A simple method for assessing the energy cost of running during incremental tests. J Appl Physiol. 2009;107:1068–1075.
    1. Glass S, Gregory B. ACSM's Metabolic Calculations Handbook. Baltimore, MD: Lippincott Williams & Wilkins; 2007.
    1. Ware JE Jr, Sherbourne CD. The MOS 36‐item short‐form health survey (SF‐36), I: conceptual framework and item selection. Med Care. 1992;30:473–483.
    1. Zigmond A, Snaith R. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67:361–370.
    1. Devilly GJ, Borkovec TD. Psychometric properties of the credibility/expectancy questionnaire. J Behav Ther Exp Psychiatry. 2000;31:73–86. DOI: 10.1016/s0005-7916(00)00012-4.
    1. Dunlay SM, Witt BJ, Allison TG, Hayes SN, Weston SA, Koepsell E, Roger VL. Barriers to participation in cardiac rehabilitation. Am Heart J. 2009;158:852–859.
    1. Chuang‐Stein C, Tong DM. The impact and implication of regression to the mean on the design and analysis of medical investigations. Stat Methods Med Res. 1997;6:115–128.
    1. Pocock SJ, Assmann SE, Enos LE, Kasten LE. Subgroup analysis, covariate adjustment and baseline comparisons in clinical trial reporting: current practice and problems. Stat Med. 2002;21:2917–2930.
    1. Sharma AM, Karmali S, Birch DW. Reporting weight loss: is simple better? Obesity (Silver Spring). 2010;18:219.
    1. Yeh GY, Mu L, Davis RB, Wayne PM. Correlates of exercise self‐efficacy in a randomized trial of mind‐body exercise in patients with chronic heart failure. J Cardiopulm Rehabil Prev. 2016;36:186–194.
    1. Caminiti G, Volterrani M, Marazzi G, Cerrito A, Massaro R, Arisi A, Franchini A, Sposato B, Rosano G. Tai Chi enhances the effects of endurance training in the rehabilitation of elderly patients with chronic heart failure. Rehabil Res Pract. 2011;2011:761958.
    1. Taylor‐Piliae RE, Silva E, Sheremeta SP. Tai Chi as an adjunct physical activity for adults aged 45 years and older enrolled in phase III cardiac rehabilitation. Eur J Cardiovasc Nurs. 2012;11:34–43. DOI: 10.1016/j.ejcnurse.2010.11.001.
    1. Lai JS, Wong MK, Lan C, Chong CK, Lien IN. Cardiorespiratory responses of Tai Chi Chuan practitioners and sedentary subjects during cycle ergometry. J Formos Med Assoc. 1993;92:894–899.
    1. Lan C, Chou SW, Chen SY, Lai JS, Wong MK. The aerobic capacity and ventilatory efficiency during exercise in Qigong and Tai Chi Chuan practitioners. Am J Chin Med. 2004;32:141–150.
    1. Lan C, Lai JS, Chen SY, Wong MK. 12‐Month Tai Chi training in the elderly: its effect on health fitness. Med Sci Sports Exerc. 1998;30:345–351.
    1. Taylor‐Piliae RE. The effectiveness of Tai Chi exercise in improving aerobic capacity: an updated meta‐analysis. Med Sport Sci. 2008;52:40–53.
    1. Schutte NM, Nederend I, Hudziak JJ, Bartels M, de Geus EJ. Twin‐sibling study and meta‐analysis on the heritability of maximal oxygen consumption. Physiol Genomics. 2016;48:210–219.
    1. Serrano‐Sanchez JA, Delgado‐Guerra S, Olmedillas H, Guadalupe‐Grau A, Arteaga‐Ortiz R, Sanchis‐Moysi J, Dorado C, Calbet JA. Adiposity and age explain most of the association between physical activity and fitness in physically active men. PLoS One. 2010;5:e13435.
    1. de Borba AT, Jost RT, Gass R, Nedel FB, Cardoso DM, Pohl HH, Reckziegel MB, Corbellini VA, Paiva DN. The influence of active and passive smoking on the cardiorespiratory fitness of adults. Multidiscip Respir Med. 2014;9:34.

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