The Association Between Preoperative Frailty and Postoperative Delirium After Cardiac Surgery
Charles H Brown 4th, Laura Max, Andrew LaFlam, Lou Kirk, Alden Gross, Rakesh Arora, Karin Neufeld, Charles W Hogue, Jeremy Walston, Aliaksei Pustavoitau, Charles H Brown 4th, Laura Max, Andrew LaFlam, Lou Kirk, Alden Gross, Rakesh Arora, Karin Neufeld, Charles W Hogue, Jeremy Walston, Aliaksei Pustavoitau
Abstract
Delirium is common after cardiac surgery, and preoperative identification of high-risk patients could guide prevention strategies. We prospectively measured frailty in 55 patients before cardiac surgery and assessed postoperative delirium using a validated chart review. The prevalence of frailty was 30.9%. Frail patients had a higher incidence of delirium (47.1%) compared with nonfrail patients (2.6%; P < 0.001). In multivariable models, the relative risk of delirium was ≥2.1-fold greater in frail compared with nonfrail patients (relative risk, 18.3; 95% confidence interval, 2.1-161.8; P = 0.009). Frailty may identify patients who would benefit from delirium-prevention strategies because of increased baseline risk for delirium.
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Source: PubMed