Biomarkers as outcome predictors in subarachnoid hemorrhage--a systematic review
Caron M Hong, Cigdem Tosun, David B Kurland, Volodymyr Gerzanich, David Schreibman, J Marc Simard, Caron M Hong, Cigdem Tosun, David B Kurland, Volodymyr Gerzanich, David Schreibman, J Marc Simard
Abstract
Context: Subarachnoid hemorrhage (SAH) has a high fatality rate and many suffer from delayed neurological deficits. Biomarkers may aid in the identification of high-risk patients, guide treatment/management and improve outcome.
Objective: The aim of this review was to summarize biomarkers of SAH associated with outcome.
Methods: An electronic database query was completed, including an additional review of reference lists to include all potential human studies.
Results: A total of 298 articles were identified; 112 were reviewed; 55 studies were included.
Conclusion: This review details biomarkers of SAH that correlate with outcome. It provides the basis for research investigating their possible translation into the management of SAH patients.
Conflict of interest statement
Declaration of interest
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.
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Source: PubMed